p-T172-PRKAA2 [cytosol]

Stable Identifier
R-HSA-200417
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-T172-AMPK alpha2
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P54646 PRKAA2
Gene Names
PRKAA2, AMPK, AMPK2
Chain
chain:1-552
Reference Genes
BioGPS Gene:5563 PRKAA2
COSMIC (genes):PRKAA2 PRKAA2
CTD Gene:5563 PRKAA2
dbSNP Gene:5563 PRKAA2
ENSEMBL:ENSG00000162409 PRKAA2
HGNC:9377 PRKAA2
KEGG Gene (Homo sapiens):5563 PRKAA2
Monarch:5563 PRKAA2
NCBI Gene:5563 PRKAA2
OMIM:600497 PRKAA2
UCSC:P54646 PRKAA2
Reference Transcript
Other Identifiers
0004730088
04150+2.7.11.1
04151+2.7.11.1
04714+2.7.11.1
04926+2.7.11.1
05163+2.7.11.1
05165+2.7.11.1
05170+2.7.11.1
11729364_at
11729365_at
11729366_at
11729367_at
16665182
186_at
207709_at
227892_at
2337719
2337720
2337721
2337725
2337728
2337729
2337730
2337732
2337733
2337734
2337735
2337736
2337737
2337738
2337739
2337741
2337743
2337744
2337745
2337747
238441_at
238489_at
240349_at
2H6D
2LTU
2YZA
3AQV
41929_at
44540
4CFE
4CFF
4ZHX
54326_at
5563
57820_r_at
5EZV
5ISO
6B1U
6B2E
6BX6
7901720
82810_at
90088_at
A0A087WXX9
A_23_P60811
A_32_P94160
AAA64745
AAH69680
AAH69740
AAH69823
AL035705
BC069680
BC069740
BC069823
CCDS605
ENSG00000162409
ENSP00000360290
ENST00000371244
ENST00000371244.8
EntrezGene:5563
EntrezGene:PRKAA2
g5453965_3p_at
GE58883
GE813527
GO:0000166
GO:0003674
GO:0003682
GO:0004672
GO:0004674
GO:0004679
GO:0004712
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005794
GO:0005829
GO:0005975
GO:0006091
GO:0006325
GO:0006464
GO:0006468
GO:0006629
GO:0006631
GO:0006633
GO:0006694
GO:0006695
GO:0006810
GO:0006853
GO:0006914
GO:0006950
GO:0007010
GO:0007049
GO:0007050
GO:0007165
GO:0007267
GO:0008150
GO:0008202
GO:0008203
GO:0008219
GO:0008610
GO:0009056
GO:0009058
GO:0010468
GO:0010494
GO:0010508
GO:0010629
GO:0014850
GO:0016055
GO:0016126
GO:0016236
GO:0016239
GO:0016241
GO:0016301
GO:0016310
GO:0016607
GO:0016740
GO:0022607
GO:0022618
GO:0030424
GO:0030425
GO:0031588
GO:0031669
GO:0032007
GO:0032991
GO:0034599
GO:0034641
GO:0035174
GO:0035404
GO:0035556
GO:0035690
GO:0042149
GO:0042304
GO:0042592
GO:0042593
GO:0042752
GO:0043025
GO:0043066
GO:0043167
GO:0043226
GO:0044281
GO:0045821
GO:0046872
GO:0047322
GO:0048511
GO:0050405
GO:0051276
GO:0055085
GO:0055089
GO:0062028
GO:0065003
GO:0070507
GO:0071277
GO:0071333
GO:0071380
GO:0097009
GO:1901796
GO:1903829
GO:1904428
GO:2000758
HGNC:9377
HPA044540
Hs.127301.0.A1_3p_at
Hs.139293.0.S1_3p_at
Hs.145568.0.A1_3p_at
Hs.86379.0.A1_3p_at
Hs.86379.0.A1_3p_x_at
ILMN_1668778
IPR000719
IPR008271
IPR011009
IPR017441
IPR028375
IPR032270
IPR039148
MIM:600497
NM_006252
NP_006243
PF00069
PF16579
PH_hs_0020627
PH_hs_0023278
PRKAA2
PRKAA2-201
SM00220
TC01000685.hg
TC01004414.hg
U06454
U06454_at
UPI00001250A9
XM_017001692
XM_017001693
XM_017001694
XP_016857181
XP_016857182
XP_016857183
XR_001737290
Participant Of
hasComponent
hasMember
Other forms of this molecule
PRKAA2 [cytosol]
p-T172-PRKAA2 [nucleoplasm]
PRKAA2 [nucleoplasm]
Inferred To
phospho-p-T172-PRKAA2 [cytosol] (Bos taurus)
phospho-p-T172-PRKAA2 [cytosol] (Caenorhabditis elegans)
phospho-p-T172-PRKAA2 [cytosol] (Canis familiaris)
phospho-p-T172-PRKAA2 [cytosol] (Danio rerio)
phospho-p-T172-PRKAA2 [cytosol] (Dictyostelium discoideum)
phospho-p-T172-PRKAA2 [cytosol] (Drosophila melanogaster)
phospho-p-T172-PRKAA2 [cytosol] (Gallus gallus)
phospho-p-T172-PRKAA2 [cytosol] (Mus musculus)
phospho-p-T172-PRKAA2 [cytosol] (Rattus norvegicus)
phospho-p-T172-PRKAA2 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T172-PRKAA2 [cytosol] (Schizosaccharomyces pombe)
phospho-p-T172-PRKAA2 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-threonine at 172
Coordinate
172
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
OpenTargets
GeneCards
ZINC target
PRO
HMDB Protein
PDB
Interactors (114)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O43741 PRKAB2  3 0.864 13
 UniProt:P54619 PRKAG1  2 0.822 10
 UniProt:Q9Y478 PRKAB1  2 0.721 4
 UniProt:Q9BVG8 KIFC3      0.666 4
 UniProt:Q04864-2 REL      0.621 3
 UniProt:Q5JR59-3 MTUS2      0.621 3
 UniProt:O75385 ULK1  7 0.589 2
 UniProt:Q15831 STK11  2 0.589 3
 UniProt:Q13131 PRKAA1  3 0.564 3
 UniProt:Q9P246 STIM2      0.564 2
 UniProt:Q6NT76 HMBX1      0.556 3
 UniProt:Q5T7B8-2 KIF24      0.556 3
 IntAct:EBI-10171679 386682      0.556 3
 UniProt:Q6FG41 Q6FG41      0.556 3
 UniProt:Q08117 TLE5  1 0.556 3
 UniProt:Q93062 RBPMS      0.556 3
 UniProt:Q96BR9 ZBT8A      0.556 3
 UniProt:Q15323 KRT31  1 0.556 3
 UniProt:Q9NPC3 CIP1      0.556 3
 UniProt:Q86Y26 NUTM1      0.556 3
 UniProt:Q9Y3Q8 T22D4      0.556 3
 UniProt:Q8N1B4 VPS52  1 0.556 3
 UniProt:Q15654 TRIP6      0.556 3
 UniProt:Q92624 APBP2      0.556 3
 UniProt:Q719H9 KCTD1  1 0.556 3
 UniProt:Q9NYB9 ABI2  2 0.556 3
 UniProt:P08151 GLI1  9 0.556 3
 UniProt:Q15233-2 NONO      0.556 3
 UniProt:Q96JM7 LMBL3      0.556 3
 UniProt:Q8NF99 ZN397      0.556 3
 UniProt:Q7Z6G3-2 NECAB2      0.556 3
 UniProt:Q8IX15-3 HOMEZ      0.556 3
 UniProt:Q13155 AIMP2  1 0.556 3
 UniProt:Q8HWS3 RFX6  1 0.556 3
 UniProt:Q8N6Y0 USBP1      0.556 3
 UniProt:P15884 TCF4  1 0.556 3
 UniProt:Q7Z3S9 NT2NA      0.556 3
 UniProt:Q8IZE3-2 SCYL3      0.488 2
 IntAct:EBI-19145652 YPEL3-51      0.488 2
 UniProt:Q9UBR4-2 LHX3      0.488 2
 UniProt:Q9ULX6 AKP8L      0.488 2
 UniProt:Q9P1Z2 CACO1      0.488 2
 UniProt:Q13137 CACO2      0.488 2
 UniProt:Q7Z5V6-2 PPP1R32      0.488 2
 UniProt:Q53EP0-3 FNDC3B      0.488 2
 IntAct:EBI-11749135 KRTAP13      0.488 2
 UniProt:Q9Y2J4 AMOTL2  1 0.488 2
 UniProt:Q9UK41-2 VPS28      0.488 2
 UniProt:Q8IZP0-5 ABI1      0.488 2
 UniProt:A8MQ03 CRTP1      0.488 2
 UniProt:Q9NQX0 PRDM6      0.488 2
 UniProt:P41219 PERI      0.488 2
 UniProt:Q86T90 K1328      0.488 2
 IntAct:EBI-11957986 HOMEZ      0.488 2
 UniProt:O75791 GRAP2  1 0.488 2
 UniProt:Q5T686 AVPI1      0.488 2
 UniProt:Q5JUK2 SOLH1      0.488 2
 UniProt:Q9NQM4 PIHD3      0.488 2
 IntAct:EBI-11522976 CCDC33      0.488 2
 UniProt:O75638-2 CTAG2      0.488 2
 UniProt:Q96B67 ARRD3      0.488 2
 UniProt:Q9NYG5-2 ANAPC11      0.488 2
 UniProt:Q9Y6C2-2 EMILIN1      0.488 2
 UniProt:Q9UKT9 IKZF3      0.488 2
 UniProt:O95208-2 EPN2      0.488 2
 UniProt:P32321 DCTD  1 0.488 2
 UniProt:P0C7W6 CC172      0.488 2
 UniProt:O00308 WWP2  1 0.488 2
 UniProt:Q6ZR03 YU004      0.488 2
 UniProt:Q7L273 KCTD9      0.488 2
 UniProt:Q9BRK4 LZTS2      0.488 2
 UniProt:Q13422-7 IKZF1      0.488 2
 UniProt:Q96L93-6 KIF16B      0.488 2
 UniProt:Q92997 DVL3  4 0.488 2
 UniProt:Q9H9H4 VPS37B  1 0.488 2
 UniProt:Q9NYB9-2 ABI2      0.488 2
 UniProt:P12524-2 P125242      0.488 2
 UniProt:Q13064 MKRN3      0.488 2
 UniProt:P31321 PRKAR1B  2 0.488 2
 UniProt:Q02446 SP4      0.488 2
 UniProt:Q6PF18 MORN3      0.488 2
 UniProt:Q9H0C1 ZMY12      0.488 2
 UniProt:Q15477 SKIV2L  1 0.488 2
 UniProt:Q3MJ62 ZSC23      0.488 2
 UniProt:P08779 KRT16  1 0.488 2
 UniProt:Q9UDV6 ZNF212  1 0.488 2
 UniProt:Q8N684-3 CPSF7      0.488 2
 UniProt:Q96CG3 TIFA  2 0.488 2
 UniProt:Q495M9 USH1G      0.488 2
 UniProt:P80188 LCN2  2 0.488 2
 UniProt:O75420 GGYF1      0.488 2
 UniProt:Q9H6Q3 SLAP2      0.488 2
 IntAct:EBI-19130346 WASHC1      0.488 2
 UniProt:Q494U1-3 PLEKHN1      0.488 2
 UniProt:Q15645 PCH2      0.488 2
 UniProt:Q96JM7-2 L3MBTL3      0.488 2
 UniProt:Q01850 CDR2      0.488 2
 UniProt:P56545-3 CTBP2      0.488 2
 UniProt:Q96F24 NRBF2      0.488 2
 UniProt:A1L4K1 FSD2      0.488 2
 UniProt:P50570 DNM2  5 0.488 2
 UniProt:P60411 KRTAP10-9  1 0.488 2
 UniProt:Q63ZY3 KANK2      0.488 2
 UniProt:A2BDD9 A2BDD9      0.488 2
 UniProt:Q6ZMT1 STAC2      0.488 2
 UniProt:Q00587-2 CDC42EP1      0.488 2
 UniProt:O43609 SPRY1  3 0.488 2
 UniProt:Q9NYA3 GOG6A      0.488 2
 UniProt:Q9Y6N9-4 USH1C      0.488 2
 UniProt:Q86YV0 RASAL3  1 0.488 2
 UniProt:Q15742 NAB2      0.488 2
 UniProt:Q9UJW9 SRTD3      0.488 2
 UniProt:O14627 CDX4      0.488 2
 UniProt:Q08379 GOLGA2  3 0.488 2