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ARPC2 [cytosol]
Stable Identifier
R-HSA-200809
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p34-ARC
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPHB-mediated forward signaling (Homo sapiens)
N-WASP binds ARP2/3 and G-actin (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate WASPs and WAVEs (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Clathrin recruits auxilins to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Dissociation of clathrin-associated proteins (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
RAB5 and GAPVD1 bind AP-2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
ARP2/3 complex [cytosol] (Homo sapiens)
ARPC2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15144 ARPC2
Gene Names
ARPC2, ARC34, PRO2446
Chain
chain:1-300
Reference Genes
BioGPS Gene:10109 ARPC2
COSMIC (genes):ARPC2 ARPC2
CTD Gene:10109 ARPC2
dbSNP Gene:10109 ARPC2
ENSEMBL:ENSG00000163466 ARPC2
HGNC:705 ARPC2
KEGG:hsa:10109 ARPC2
Monarch:10109 ARPC2
NCBI Gene:10109 ARPC2
OMIM:604224 ARPC2
UCSC:O15144 ARPC2
Reference Transcript
RefSeq:NM_005731.3 ARPC2
RefSeq:NM_152862.2 ARPC2
Other Identifiers
10109
11742870_at
16890763
1718_at
207988_PM_s_at
207988_s_at
208679_PM_s_at
208679_s_at
213513_PM_x_at
213513_x_at
2527607
2527608
2527609
2527610
2527611
2527615
2527617
2527618
2527619
2527620
2527622
2527623
2527624
2527625
2527626
2527627
2527628
2527629
2527630
2527631
2527632
2527636
2527637
2527638
2527640
2527641
2527642
2527644
2527646
2527647
2527648
2527649
44310_at
8048234
A_14_P118018
A_14_P122630
A_23_P102122
GE59209
GO:0003779
GO:0005198
GO:0005200
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005829
GO:0005856
GO:0005885
GO:0005886
GO:0005925
GO:0008092
GO:0010592
GO:0015629
GO:0030027
GO:0030041
GO:0030672
GO:0030838
GO:0031252
GO:0031410
GO:0034314
GO:0035861
GO:0036195
GO:0042995
GO:0043005
GO:0043226
GO:0045202
GO:0048870
GO:0051015
GO:0065003
GO:0070062
GO:0070358
GO:0098793
GO:0098794
GO:0098978
GO:1900026
HMNXSV003052085
Hs.252280.1.A1_3p_s_at
ILMN_1792489
ILMN_1810200
ILMN_2255021
PH_hs_0004769
PH_hs_0035481
TC02001295.hg
U50523_at
g12751114_3p_a_at
Participates
as a component of
ARP2/3 complex [cytosol] (Homo sapiens)
ARP2/3 complex (ATP bound) [cytosol] (Homo sapiens)
Inferred To
Arpc2 [cytosol]
(Drosophila melanogaster)
Arpc2 [cytosol]
(Mus musculus)
Arpc2 [cytosol]
(Rattus norvegicus)
arpc2 [cytosol]
(Danio rerio)
arpc2 [cytosol]
(Xenopus tropicalis)
arc2 [cytosol]
(Schizosaccharomyces pombe)
ARC35 [cytosol]
(Saccharomyces cerevisiae)
arx-4 [cytosol]
(Caenorhabditis elegans)
arcB [cytosol]
(Dictyostelium discoideum)
ARPC2 [cytosol]
(Bos taurus)
ARPC2 [cytosol]
(Canis familiaris)
ARPC2 [cytosol]
(Gallus gallus)
ARPC2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_690601.1
,
NP_005722.1
ENSEMBL
ENST00000295685
,
ENSP00000327137
,
ENSP00000295685
,
ENST00000315717
OpenTargets
ENSG00000163466
HPA
ENSG00000163466-ARPC2
PRO
O15144
Pharos - Targets
O15144
GlyGen
O15144
PDB
6UHC
,
6YW6
,
6YW7
,
8P94
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16236 NFE2L2
13
p-S40-NFE2L2 [nucleoplasm]
(R-HSA-9715109)
p-S,T-NFE2L2 [nucleoplasm]
(R-HSA-9715110)
p-S40-NFE2L2 [cytosol]
(R-HSA-8932290)
p-S,T-NFE2L2 [cytosol]
(R-HSA-8932311)
NFE2L2 [cytosol]
(R-HSA-201566)
p-S,T-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760033)
p-S40-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760018)
ub-NFE2L2 [cytosol]
(R-HSA-9758077)
ub-p-S335, S338,T-NFE2L2 [nucleoplasm]
(R-HSA-9762055)
ub-p-S40, S335, S338- NFE2L2 [nucleoplasm]
(R-HSA-9762058)
p-S344, S347,T-NFE2L2 [nucleoplasm]
(R-HSA-9762048)
p-S40, S344, S347- NFE2L2 [nucleoplasm]
(R-HSA-9762050)
p-S,T,S558-NFE2L2 [nucleoplasm]
(R-HSA-9795736)
0.625
5
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.527
10
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
4
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