BMP2 binds to the receptor complex

Stable Identifier
R-HSA-201457
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The mature dimeric BMP2 binds with high affinity to its signalling receptor, the type II receptor serine/threonine kinase. The type II receptor is known to form dimeric complexes even in the absence of BMP2 (Rosenzweig et al.1995).

Literature References
PubMed ID Title Journal Year
7644468 Cloning and characterization of a human type II receptor for bone morphogenetic proteins

Rosenzweig, BL, Imamura, T, Okadome, T, Cox, GN, Yamashita, H, ten Dijke, P, Heldin, CH, Miyazono, K

Proc Natl Acad Sci U S A 1995
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