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PTN:p-7Y ALK dimer [plasma membrane]
Stable Identifier
R-HSA-201534
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ALK (Homo sapiens)
ALK autophosphorylation (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
ALK-stimulated MYCN gene expression (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK binds FRS2 (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:FRS2 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK binds JAK3 (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:JAK3 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK binds PLCG1 (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:PLCG1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK binds SHC1 (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:SHC1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK binds SRC (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:SRC [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK dimer binds IRS1 (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:IRS1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK phosphorylates FRS2 (Homo sapiens)
Active ALK:FRS2 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:p-6Y FRS2 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK phosphorylates IRS1 (Homo sapiens)
Active ALK:IRS1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:pY-IRS1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK phosphorylates JAK3 (Homo sapiens)
Active ALK:JAK3 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:p-Y980 JAK3 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK phosphorylates PLCG1 (Homo sapiens)
Active ALK:PLCG1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:p-4Y PLCG1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK phosphorylates SHC1 (Homo sapiens)
Active ALK:SHC1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:p-3Y SHC1 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK phosphorylates SRC (Homo sapiens)
Active ALK:SRC [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:p-Y419 SRC [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK recruits PI3K (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:PI3K [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
MDK and PTN in ALK signaling (Homo sapiens)
PTPRZ dephosphorylates ligand-bound ALK dimers (Homo sapiens)
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
PI3K synthesizes PIP3 downstream of ALK (Homo sapiens)
Active ALK:PI3K [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
PTPN6 dephosphorylates JAK3 (Homo sapiens)
Active ALK:JAK3 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Active ALK:p-Y980 JAK3 [plasma membrane] (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
STAT3 is phosphorylated downstream of active ALK (Homo sapiens)
Active ALK dimer [plasma membrane] (Homo sapiens)
PTN:p-7Y ALK dimer [plasma membrane] (Homo sapiens)
Participants
components
p-7Y ALK dimer [plasma membrane]
(Homo sapiens)
PTN [extracellular region]
(Homo sapiens)
Participates
as a member of
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Homo sapiens)
as a candidate of
Active ALK dimer [plasma membrane] (Homo sapiens)
Inferred To
PTN:p-7Y ALK dimer [plasma membrane]
(Bos taurus)
PTN:p-7Y ALK dimer [plasma membrane]
(Canis familiaris)
PTN:p-7Y ALK dimer [plasma membrane]
(Danio rerio)
PTN:p-7Y ALK dimer [plasma membrane]
(Gallus gallus)
PTN:p-7Y ALK dimer [plasma membrane]
(Mus musculus)
PTN:p-7Y ALK dimer [plasma membrane]
(Rattus norvegicus)
PTN:p-7Y ALK dimer [plasma membrane]
(Sus scrofa)
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