Reactome | KTN1 [endoplasmic reticulum membrane]

KTN1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-201604

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Kinectin

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q86UP2 KTN1

Gene Names

KTN1, CG1, KIAA0004

Chain

chain:1-1357

Reference Genes

BioGPS Gene:3895 KTN1

COSMIC (genes):KTN1 KTN1

CTD Gene:3895 KTN1

dbSNP Gene:3895 KTN1

ENSEMBL:ENSG00000126777 KTN1

ENSEMBL_homo_sapiens_GENE:ENSG00000126777.18 KTN1

HGNC:6467 KTN1

KEGG Gene (Homo sapiens):3895 KTN1

Monarch:3895 KTN1

NCBI Gene:3895 KTN1

OMIM:600381 KTN1

UCSC:Q86UP2 KTN1

Reference Transcript

Other Identifiers

11717070_x_at

11717071_at

11717072_x_at

11732409_a_at

11743491_x_at

11743492_s_at

11743493_x_at

11744926_x_at

11747672_a_at

11756394_a_at

11758171_s_at

16784412

200914_PM_x_at

200914_x_at

200915_PM_x_at

200915_x_at

214709_PM_s_at

214709_s_at

32846_s_at

3536909

3536922

3536926

3536927

3536928

3536929

3536930

3536931

3536932

3536933

3536934

3536935

3536938

3536939

3536940

3536942

3536943

3536944

3536945

3536946

3536947

3536948

3536949

3536950

3536951

3536954

3536955

3536956

3536958

3536960

3536961

3536962

3536964

3536965

3536966

3536967

3536969

3536972

3536974

3536979

3536984

3536987

3536990

3536992

3536994

3536996

3536998

3537000

3537003

3537005

3537007

3537009

3537013

3537014

3537015

3895

7974483

A_14_P120568

A_14_P123617

A_23_P106131

A_33_P3348639

GE61757

GO:0003723

GO:0005515

GO:0005783

GO:0005788

GO:0005789

GO:0005886

GO:0007018

GO:0008092

GO:0015031

GO:0016020

GO:0019894

GO:0043226

GO:0045296

HMNXSV003055131

Hs.211577.0.S1_3p_a_at

Hs.211577.1.S1_3p_a_at

ILMN_1740523

ILMN_2339202

PH_hs_0028242

TC14000326.hg

Z22551_at

g4826813_3p_a_at

g4826813_3p_x_at

Participates

as a member of

RHOG endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)

as a component of

KTN1 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

KTN1 [plasma membrane]

p-KTN1 [endoplasmic reticulum lumen]

KTN1 [endoplasmic reticulum lumen]

Inferred To

ktn1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

KTN1 [endoplasmic reticulum membrane] (Bos taurus)

KTN1 [endoplasmic reticulum membrane] (Canis familiaris)

KTN1 [endoplasmic reticulum membrane] (Gallus gallus)

KTN1 [endoplasmic reticulum membrane] (Sus scrofa)

Ktn1 [endoplasmic reticulum membrane] (Mus musculus)

Ktn1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_016876772.1, NP_004977.2, NP_001072990.1, XP_016876771.1, XP_011535055.1, XP_016876767.1, XP_006720202.1, XP_011535053.1, NP_001072989.1, XP_006720201.1, NP_001257943.1

OpenTargets

ENSG00000126777

GeneCards

Q86UP2

HPA

ENSG00000126777-KTN1

Ensembl

ENST00000413890, ENST00000438792, ENSG00000126777, ENSP00000394992, ENST00000395311, ENSP00000432149, ENST00000395308, ENST00000395314, ENST00000395309, ENSP00000378719, ENSP00000378720, ENSP00000378725, ENSP00000378722, ENST00000459737, ENSP00000391964

PRO

Q86UP2

Pharos - Targets

Q86UP2

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BXN2 CLEC7A	2	CLEC7A [plasma membrane] (R-HSA-2130683) p-Y15-CLEC7A [plasma membrane] (R-HSA-5607641)	0.556	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	11