AKT2 [plasma membrane]

Stable Identifier
R-HSA-202053
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RAC-beta serine/threonine protein kinase , RAC-PK-beta, Protein kinase Akt-2, Protein kinase B, beta, PKB beta
Icon
AKT2 [plasma membrane] icon
AKT2 [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P31751 AKT2
Gene Names
AKT2
Chain
chain:1-481
Reference Genes
BioGPS Gene:208 AKT2
COSMIC (genes):AKT2 AKT2
CTD Gene:208 AKT2
dbSNP Gene:208 AKT2
ENSEMBL:ENSG00000105221 AKT2
ENSEMBL_homo_sapiens_GENE:ENSG00000105221.18 AKT2
HGNC:392 AKT2
KEGG Gene (Homo sapiens):208 AKT2
Monarch:208 AKT2
NCBI Gene:208 AKT2
OMIM:164731 AKT2
UCSC:P31751 AKT2
Reference Transcript
Other Identifiers
11731469_at
11731470_at
11731471_a_at
11746138_s_at
11746139_a_at
11747947_a_at
11749525_a_at
11756698_a_at
11756699_x_at
11757813_x_at
11761086_x_at
2023_g_at
203809_PM_s_at
203809_s_at
208
211453_PM_s_at
211453_s_at
225471_PM_s_at
225471_s_at
226156_PM_at
226156_at
236664_PM_at
236664_at
3862470
3862472
3862473
3862474
3862475
3862476
3862477
3862478
3862479
3862480
3862481
3862482
3862483
3862484
3862489
3862490
3862491
3862494
3862497
3862498
3862500
3862503
3862505
3862506
3862508
3862509
3862511
3862512
3862513
3862528
40972_at
57350_at
78734_s_at
8036840
87854_s_at
A_23_P208870
A_23_P373475
A_24_P359267
A_33_P3381647
A_33_P3400171
GE81047
GE86894
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005886
GO:0005938
GO:0005975
GO:0005977
GO:0005978
GO:0006006
GO:0006091
GO:0006417
GO:0006468
GO:0006629
GO:0006886
GO:0006915
GO:0007165
GO:0008286
GO:0008643
GO:0010748
GO:0010907
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0030334
GO:0030335
GO:0031410
GO:0032000
GO:0032287
GO:0032587
GO:0032869
GO:0035556
GO:0036211
GO:0043226
GO:0043231
GO:0045444
GO:0045725
GO:0046326
GO:0046872
GO:0048856
GO:0048870
GO:0051726
GO:0055085
GO:0060644
GO:0061024
GO:0071486
GO:0072659
GO:0090314
GO:0097473
GO:0098772
GO:0106310
GO:0140096
GO:0140677
GO:2000147
HMNXSV003008065
Hs.182278.4.S1_3p_a_at
Hs.182278.5.S1_3p_at
Hs.326445.0.S1_3p_a_at
Hs.98325.0.A1_3p_at
ILMN_1743347
M95936_s_at
PH_hs_0016190
PH_hs_0035792
g337490_3p_a_at
Participates
as a candidate of
Other forms of this molecule
p-T309,S474-AKT2 [plasma membrane]
p-T309-AKT2 [cytosol]
AKT2 [cytosol]
p-S474-AKT2 [plasma membrane]
p-T309,S474-AKT2 [cytosol]
p-T309,S474-AKT2 [nucleoplasm]
Inferred To
AKT2 [plasma membrane] (Caenorhabditis elegans)
AKT2 [plasma membrane] (Danio rerio)
AKT2 [plasma membrane] (Dictyostelium discoideum)
AKT2 [plasma membrane] (Drosophila melanogaster)
AKT2 [plasma membrane] (Mus musculus)
AKT2 [plasma membrane] (Rattus norvegicus)
AKT2 [plasma membrane] (Saccharomyces cerevisiae)
AKT2 [plasma membrane] (Schizosaccharomyces pombe)
Homologues of AKT2 [plasma membrane] (Caenorhabditis elegans)
Homologues of AKT2 [plasma membrane] (Dictyostelium discoideum)
Homologues of AKT2 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of AKT2 [plasma membrane] (Schizosaccharomyces pombe)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (12)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P31749 AKT1  14 0.641 3
 UniProt:Q9C0C9 UBE2O  1 0.623 4
 UniProt:P53804 TTC3      0.581 5
 UniProt:O60504 SORBS3  1 0.556 3
 UniProt:Q04864-2 REL      0.556 3
 IntAct:EBI-22313194 CCSB ORF ID      0.556 3
 UniProt:Q6FHY5 Q6FHY5      0.556 3
 UniProt:Q9NRD5 PICK1  2 0.556 3
 UniProt:Q00526 CDK3      0.527 2
 UniProt:P24468 NR2F2  1 0.527 2
 UniProt:P0CG47 UBB  20 0.527 2
 UniProt:P08238 HSP90AB1  6 0.524 2
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