HSP90 binds eNOS:Caveolin-1:CaM complex

Stable Identifier
R-HSA-202129
Type
Reaction
Species
Homo sapiens
Compartment
cytosol, plasma membrane
Locations in the PathwayBrowser
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Summation

HSP90 interacts with the amino terminus of eNOS (amino acids 442-600) and facilitates displacement of caveolin by calmodulin (CaM).

Literature References
PubMed ID Title Journal Year
9580552 Dynamic activation of endothelial nitric oxide synthase by Hsp90 Nature 1998
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
HSP90 binds eNOS:Caveolin-1:CaM complex (Canis familiaris)
HSP90 binds eNOS:Caveolin-1:CaM complex (Mus musculus)