Reactome | LOXL3 [extracellular region]

LOXL3 [extracellular region]

Stable Identifier

R-HSA-2022100

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

proLOXL3, Lysyl oxidase homolog 3, LOXL3_HUMAN

Locations in the PathwayBrowser

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Extracellular matrix organization (Homo sapiens)

- Collagen formation (Homo sapiens)
  - Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
    - Crosslinking of collagen fibrils (Homo sapiens)
      - Prolysyl oxidase activation (Homo sapiens)
        
        Prolysyl oxidases [extracellular region] (Homo sapiens)
        
        LOXL3 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:P58215 LOXL3

Gene Names

LOXL3, LOXL

Chain

signal peptide:1-25, chain:26-753

Reference Genes

BioGPS Gene:84695 LOXL3

COSMIC (genes):LOXL3 LOXL3

CTD Gene:84695 LOXL3

dbSNP Gene:84695 LOXL3

ENSEMBL:ENSG00000115318 LOXL3

ENSEMBL_homo_sapiens_GENE:ENSG00000115318.12 LOXL3

HGNC:13869 LOXL3

KEGG Gene (Homo sapiens):84695 LOXL3

Monarch:84695 LOXL3

NCBI Gene:84695 LOXL3

OMIM:607163 LOXL3

UCSC:P58215 LOXL3

Reference Transcript

Other Identifiers

11721392_a_at

11759968_at

16899357

228253_PM_at

228253_at

2560287

2560288

2560289

2560290

2560291

2560293

2560294

2560295

2560296

2560297

2560298

2560299

2560300

2560301

2560302

2560307

2560309

2560310

2560311

2560314

3812172

8053231

84695

A_23_P39799

A_24_P88763

GE79689

GO:0001837

GO:0001968

GO:0002376

GO:0003824

GO:0004720

GO:0005044

GO:0005507

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0006351

GO:0006355

GO:0006954

GO:0007155

GO:0016020

GO:0016491

GO:0016641

GO:0018057

GO:0021510

GO:0023052

GO:0030154

GO:0030198

GO:0030199

GO:0030312

GO:0030324

GO:0031012

GO:0036211

GO:0038024

GO:0043226

GO:0045892

GO:0046872

GO:0048856

GO:0060021

GO:0061053

GO:0062023

GO:0140096

GO:1905590

GO:2000329

GO:2001046

HMNXSV003039662

Hs.115721.2.A1_3p_at

ILMN_1733515

PH_hs_0016466

TC02002002.hg

Participates

as a candidate of

Prolysyl oxidases [extracellular region] (Homo sapiens)

Other forms of this molecule

LOXL3(26-?) [extracellular region]

LOXL3(?-753) [extracellular region]

Inferred To

Loxl2 [extracellular region] (Drosophila melanogaster)

Loxl3 [extracellular region] (Rattus norvegicus)

loxl3b [extracellular region] (Danio rerio)

LOXL3 [extracellular region] (Bos taurus)

LOXL3 [extracellular region] (Canis familiaris)

LOXL3 [extracellular region] (Gallus gallus)

LOXL3 [extracellular region] (Mus musculus)

LOXL3 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_115992.1, NP_001276094.1, XP_011531436.1, NP_001276093.1, XP_016860601.1

OpenTargets

ENSG00000115318

IntEnz

1.4.3.13

HPA

ENSG00000115318-LOXL3

GeneCards

P58215

Ensembl

ENST00000393937, ENSG00000115318, ENSP00000264094, ENST00000264094, ENSP00000377512

PRO

P58215

Pharos - Targets

P58215

Orphanet

24679

HMDB Protein

HMDBP08251

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