Neprilysin hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-7)

Stable Identifier
R-HSA-2022396
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Neprilysin Hydrolyzes Angiotensin I to Yield Angiotensin-(1-7)
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Neprilysin hydrolyzes angiotensin-(1-10) (angiotensin I) directly to angiotensin-(1-7) (Rice et al. 2004).

Literature References
PubMed ID Title Journal Year
15283675 Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism

Rice, GI, Thomas, DA, Grant, PJ, Turner, AJ, Hooper, NM

Biochem J 2004
Participants
Participant Of
Event Information
Go Biological Process
Catalyst Activity
Catalyst Activity
Title
metallopeptidase activity of MME [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created