p-Y394-LCK [cytosol]

Stable Identifier
R-HSA-202308
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-Y394-LCK(1-509), Lck phosphorylated at tyrosine 394
p-Y394-LCK [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
2824653 Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens

Streuli, M, Hall, LR, Saga, Y, Schlossman, SF, Saito, H

J Exp Med 1987
External Reference Information
External Reference
Gene Names
LCK
Chain
initiator methionine:1, chain:2-509
Other Identifiers
0007100253
11740979_x_at
11752568_a_at
11752569_x_at
11755231_a_at
11756006_x_at
16662052
204890_s_at
204891_3p_s_at
204891_s_at
2059_s_at
2328842
2328843
2328845
2328847
2328848
2328850
2328852
2328853
2328854
2328855
2328856
2328857
2328859
2328860
2328863
2328864
2328865
2328866
2328867
33238_at
3932
7899753
A_23_P103361
A_33_P3382746
GE59664
GO:0000166
GO:0000242
GO:0001772
GO:0001784
GO:0002376
GO:0003674
GO:0004672
GO:0004713
GO:0004715
GO:0004722
GO:0005102
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0006464
GO:0006468
GO:0006470
GO:0006810
GO:0006882
GO:0006919
GO:0006950
GO:0007155
GO:0007165
GO:0007169
GO:0008022
GO:0008150
GO:0008219
GO:0008283
GO:0016020
GO:0016032
GO:0016301
GO:0016310
GO:0016740
GO:0016791
GO:0018108
GO:0019899
GO:0019901
GO:0019903
GO:0030097
GO:0030154
GO:0030168
GO:0030217
GO:0031234
GO:0031295
GO:0034116
GO:0038083
GO:0040011
GO:0042127
GO:0042169
GO:0042493
GO:0042592
GO:0042608
GO:0042609
GO:0042610
GO:0042802
GO:0043167
GO:0043226
GO:0043548
GO:0044403
GO:0045121
GO:0048856
GO:0048870
GO:0050690
GO:0050852
GO:0050853
GO:0050862
GO:0050870
GO:0050900
GO:0051117
GO:0051209
GO:0051249
GO:0051897
GO:0055085
GO:0070062
GO:1903039
GO:2001244
ILMN_2277426
ILMN_2279844
ILMN_2377109
PH_hs_0000240
TC01000426.hg
U23852_s_at
g460965_3p_s_at
g4885448_3p_at
g4885448_3p_s_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
O4'-phospho-L-tyrosine at 394
Coordinate
394
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (38)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P08575 PTPRC  2 0.851 7
 UniProt:Q07666 KHDRBS1  3 0.835 5
 UniProt:P22575 TIP      0.815 9
 UniProt:Q9Y2R2 PTPN22  1 0.783 6
 UniProt:Q9NP31 SH2D2A  1 0.77 12
 UniProt:P22681 CBL  6 0.75 4
 UniProt:P43405 SYK  6 0.748 8
 UniProt:P06239 LCK  4 0.719 5
 UniProt:P43403 ZAP70  3 0.702 3
 UniProt:P01730 CD4  4 0.702 3
 UniProt:Q9H204 MED28  1 0.691 4
 UniProt:Q13444 ADAM15  1 0.667 4
 UniProt:Q12959 DLG1  4 0.656 3
 UniProt:P08238 HSP90AB1  6 0.641 4
 UniProt:P29350 PTPN6  5 0.623 5
 UniProt:P20963 CD247      0.609 2
 UniProt:O14672 ADAM10  6 0.602 3
 UniProt:P08921  1 0.602 11
 UniProt:P20749 BCL3      0.591 3
 UniProt:P07900 HSP90AA1  8 0.564 3
 UniProt:Q13094 LCP2  2 0.564 2
 IntAct:EBI-7111687 TIP      0.558 2
 UniProt:P23771 GATA3  2 0.556 3
 UniProt:Q5VV42 CDKAL1  1 0.556 3
 UniProt:Q9BRK4 LZTS2      0.556 3
 UniProt:O60880 SH2D1A  1 0.547 2
 UniProt:P0CG48 UBC  325 0.544 2
 UniProt:Q63767  4 0.532 3
 UniProt:Q8N1K5-1 THEMIS      0.525 3
 UniProt:O43561 LAT  3 0.525 2
 UniProt:Q13283 G3BP1      0.524 2
 UniProt:P28482 MAPK1  18 0.524 2
 UniProt:Q04759 PRKCQ  9 0.499 2
 UniProt:P40763-2 STAT3      0.488 2
 UniProt:O60496 DOK2  1 0.488 2
 UniProt:P32577  2 0.482 2
 UniProt:P04150 NR3C1  3 0.463 3
 UniProt:Q8TDQ0 HAVCR2  1 0.462 2
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