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PLCH2 [plasma membrane]
Stable Identifier
R-HSA-2023887
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
KIAA0450, PLCL4
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Homo sapiens)
PLCdegh [plasma membrane] (Homo sapiens)
PLCH2:Ca2+ [plasma membrane] (Homo sapiens)
PLCH2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75038 PLCH2
Gene Names
PLCH2, KIAA0450, PLCL4
Chain
chain:1-1416
Reference Genes
BioGPS Gene:9651 PLCH2
COSMIC (genes):PLCH2 PLCH2
CTD Gene:9651 PLCH2
dbSNP Gene:9651 PLCH2
ENSEMBL:ENSG00000149527 PLCH2
ENSEMBL_homo_sapiens_GENE:ENSG00000149527.18 PLCH2
ENSEMBL_homo_sapiens_GENE:ENSG00000276429.3 PLCH2
HGNC:29037 PLCH2
KEGG Gene (Homo sapiens):9651 PLCH2
Monarch:9651 PLCH2
NCBI Gene:9651 PLCH2
OMIM:612836 PLCH2
UCSC:O75038 PLCH2
Reference Transcript
RefSeq:NM_001303012.1 PLCH2
RefSeq:NM_014638.3 PLCH2
RefSeq:NM_001303013.1 PLCH2
Other Identifiers
11755134_a_at
16658023
206080_PM_at
206080_at
2316650
2316663
2316664
2316665
2316666
2316667
2316669
2316672
2316673
2316674
2316677
2316680
2316682
2316683
2316684
2316685
2316686
2316687
2316692
2316693
2316695
2316696
2316697
2316701
2316702
2316703
2316704
2316711
2316712
2316713
2316718
2316719
2316720
2316721
2316722
2316723
2316724
2316725
2316726
2316727
2316728
35454_at
7897089
9651
A_14_P116207
A_24_P21887
A_24_P372833
A_24_P62469
GE81948
GO:0003824
GO:0004435
GO:0004629
GO:0005509
GO:0005575
GO:0005737
GO:0005886
GO:0006629
GO:0007165
GO:0007200
GO:0008081
GO:0016020
GO:0016042
GO:0016787
GO:0023052
GO:0035556
GO:0046488
GO:0046872
GO:0048015
GO:0051209
GO:0055065
GO:0055085
HMNXSV003040544
ILMN_1748410
ILMN_2061565
PH_hs_0041170
TC01000060.hg
g7662133_3p_at
Participates
as a component of
PLCH2:Ca2+ [plasma membrane] (Homo sapiens)
Inferred To
PLCH2 [plasma membrane]
(Bos taurus)
PLCH2 [plasma membrane]
(Canis familiaris)
PLCH2 [plasma membrane]
(Dictyostelium discoideum)
PLCH2 [plasma membrane]
(Gallus gallus)
PLCH2 [plasma membrane]
(Mus musculus)
PLCH2 [plasma membrane]
(Plasmodium falciparum)
PLCH2 [plasma membrane]
(Saccharomyces cerevisiae)
PLCH2 [plasma membrane]
(Schizosaccharomyces pombe)
PLCH2 [plasma membrane]
(Sus scrofa)
Plch2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001289942.1
,
NP_055453.2
,
NP_001289941.1
Guide to Pharmacology - Targets
1415
OpenTargets
ENSG00000149527
GeneCards
O75038
HPA
ENSG00000149527-PLCH2
Ensembl
ENST00000378486
,
ENST00000419816
,
ENST00000449969
,
ENSP00000481938
,
ENSG00000149527
,
ENSP00000367747
,
ENSP00000486186
,
ENSP00000487140
,
ENST00000626246
,
ENST00000620687
,
ENST00000627854
,
ENSP00000389803
,
ENSG00000276429
,
ENSP00000397289
PRO
O75038
Pharos - Targets
O75038
HMDB Protein
HMDBP01851
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