Reactome | MALT1 [cytosol]

MALT1 [cytosol]

Stable Identifier

R-HSA-202461

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Mucosa-associated lymphoid tissue lymphoma translocation protein 1

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Locations in the PathwayBrowser for interactor UniProt:Q9BXL7 CARD11

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External Reference Information

External Reference

UniProt:Q9UDY8 MALT1

Gene Names

MALT1, MLT

Chain

initiator methionine:1, chain:2-824

Reference Genes

COSMIC (genes):MALT1 MALT1

ENSEMBL:ENSG00000172175 MALT1

HGNC:6819 MALT1

UCSC:Q9UDY8 MALT1

Participates

as an input of

as a component of

as a repeated unit of

MALT1 oligomer [cytosol] (Homo sapiens)

Inferred To

Homologues of MALT1 [cytosol] (Dictyostelium discoideum)

malt-1 [cytosol] (Caenorhabditis elegans)

malt1 [cytosol] (Xenopus tropicalis)

pcp [cytosol] (Dictyostelium discoideum)

PCASP1 [cytosol] (Gallus gallus)

Malt1 [cytosol] (Mus musculus)

Malt1 [cytosol] (Rattus norvegicus)

MALT1 [cytosol] (Bos taurus)

MALT1 [cytosol] (Canis familiaris)

MALT1 [cytosol] (Dictyostelium discoideum)

MALT1 [cytosol] (Sus scrofa)

Cross References

Guide to Pharmacology - Targets

2983

ENSEMBL

ENST00000649217, ENSG00000172175, ENSP00000304161, ENST00000345724, ENSP00000497997

OpenTargets

ENSG00000172175

HPA

ENSG00000172175-MALT1

PRO

Q9UDY8

Pharos - Targets

Q9UDY8

GlyGen

Q9UDY8

Orphanet

MALT1

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95999 BCL10	3	K48polyUb-BCL10 [cytosol] (R-HSA-8939329) BCL10 [cytosol] (R-HSA-202447) p-BCL10 [cytosol] (R-HSA-202488)	0.947	25
UniProt:Q9Y4K3 TRAF6	8	TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [endosome membrane] (R-HSA-450272) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) K48polyUb-TRAF6 [cytosol] (R-HSA-6783233)	0.688	5
UniProt:Q9Y6K9 IKBKG	12	IKBKG [cytosol] (R-HSA-168108) Ub-285-IKBKG [cytosol] (R-HSA-741397) K63polyUb-IKBKG [cytosol] (R-HSA-202530) IKBKG [nucleoplasm] (R-HSA-4755413) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG D406V [cytosol] (R-HSA-5262943)	0.656	4
UniProt:Q9BXL7 CARD11	5	p-S559,S644,S652-CARD11 [plasma membrane] (R-HSA-1168564) CARD11 [plasma membrane] (R-HSA-2685592) p-S559,S652-CARD11 [cytosol] (R-HSA-2685625) CARD11 [cytosol] (R-HSA-202161) p-S552-CARD11 [cytosol] (R-HSA-202438)	0.589	2
UniProt:Q9UDY8 MALT1	1	MALT1 [cytosol] (R-HSA-202461)	0.558	2
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-386-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783067) Ub-6-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783122)	0.524	4
UniProt:Q13501 SQSTM1	7	SQSTM1 [cytosol] (R-HSA-193937) SQSTM1 [nucleoplasm] (R-HSA-210961) ub K420 p-S349 SQSTM1 [cytosol] (R-HSA-9766536) p-S349 SQSTM1 [cytosol] (R-HSA-9766524) K7 ub-SQSTM1 [cytosol] (R-HSA-9759088) SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711954) SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711967)	0.524	2
UniProt:Q14790 CASP8	8	CASP8(1-479) [cytosol] (R-HSA-57031) CASP8(1-216) [cytosol] (R-HSA-933456) CASP8(217-374) [cytosol] (R-HSA-75975) CASP8(375-384) [cytosol] (R-HSA-933460) CASP8(385-479) [cytosol] (R-HSA-76158) CASP8(385-479) [mitochondrial outer membrane] (R-HSA-351828) CASP8(217-374) [mitochondrial outer membrane] (R-HSA-351869) CASP8(1-374) [cytosol] (R-HSA-3465404)	0.499	10
UniProt:P48729 CSNK1A1	3	CSNK1A1 [nucleoplasm] (R-HSA-9943726) CSNK1A1 [cytosol] (R-HSA-195263) CSNK1A1 [cilium] (R-HSA-5632507)	0.499	7

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