I-Smad competes with Co-Smad for R-Smad1/5/8

Stable Identifier
R-HSA-202626
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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I-SMAD selectively antagonizes BMP-activated Smad1/5/9 by acting as a CO-SMAD decoy.

Literature References
PubMed ID Title Journal Year
9436979 Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

Hata, A, Lagna, G, Massague, J, Hemmati-Brivanlou, A

Genes Dev 1998
Participants
Participant Of
hasEvent
Event Information
Orthologous Events
Authored
Reviewed
Created