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p-SAV1 [cytosol]
Stable Identifier
R-HSA-2028276
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
phosphorylated SAV1, phosphorylated Protein salvador homolog 1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hippo (Homo sapiens)
Cleavage of p-STK3 (p-MST2) by caspase 3 (Homo sapiens)
p-STK3/N:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
p-STK3:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Cleavage of p-STK4 (p-MST1) by caspase 3 (Homo sapiens)
p-STK4/N:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
p-STK4:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Homo sapiens)
p-STK3/N:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Homo sapiens)
p-STK3:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Homo sapiens)
p-STK4:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Homo sapiens)
p-STK4/N:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)
p-STK3:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)
p-STK3/N:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Homo sapiens)
p-STK4:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Homo sapiens)
p-STK4/N:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Homo sapiens)
p-STK3:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Homo sapiens)
p-STK4:p-SAV1 [cytosol] (Homo sapiens)
p-SAV1 dimer [cytosol] (Homo sapiens)
p-SAV1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H4B6 SAV1
Gene Names
SAV1, WW45
Chain
chain:1-383
Reference Genes
BioGPS Gene:60485 SAV1
COSMIC (genes):SAV1 SAV1
CTD Gene:60485 SAV1
dbSNP Gene:60485 SAV1
ENSEMBL:ENSG00000151748 SAV1
ENSEMBL_homo_sapiens_GENE:ENSG00000151748.15 SAV1
HGNC:17795 SAV1
KEGG Gene (Homo sapiens):60485 SAV1
Monarch:60485 SAV1
NCBI Gene:60485 SAV1
OMIM:607203 SAV1
UCSC:Q9H4B6 SAV1
Reference Transcript
RefSeq:NM_021818.3 SAV1
Other Identifiers
11722240_a_at
11722241_x_at
11749806_a_at
16792798
218276_PM_s_at
218276_s_at
222573_PM_s_at
222573_s_at
234491_PM_s_at
234491_s_at
3564029
3564030
3564031
3564032
3564033
3564034
3564035
3564036
3564037
3564041
3564042
3564049
3564050
3564051
3564052
3564055
3564056
3564057
3564058
3564059
42427_i_at
42428_r_at
60485
61871_r_at
65587_at
7979033
A_23_P65555
A_24_P287473
GE61843
GO:0001942
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006915
GO:0007165
GO:0008285
GO:0012501
GO:0023052
GO:0030154
GO:0030216
GO:0035329
GO:0042127
GO:0042802
GO:0043065
GO:0043226
GO:0045600
GO:0046620
GO:0048856
GO:0050673
GO:0050680
GO:0050821
GO:0051091
GO:0060038
GO:0060044
GO:0060090
GO:0060412
GO:0060487
GO:0060575
GO:0097283
GO:1902174
GO:2000036
HMNXSV003004185
Hs.288906.0.A1_3p_a_at
Hs.288906.1.A1_3p_a_at
ILMN_2050654
PH_hs_0023289
PH_hs_0040761
TC14001122.hg
g11141888_3p_a_at
Participates
as a component of
p-SAV1 dimer [cytosol] (Homo sapiens)
Other forms of this molecule
SAV1 [cytosol]
Inferred To
phospho-sav-1 [cytosol]
(Caenorhabditis elegans)
phospho-Sav1 [cytosol]
(Mus musculus)
phospho-Sav1 [cytosol]
(Rattus norvegicus)
phospho-sav [cytosol]
(Drosophila melanogaster)
phospho-sav1 [cytosol]
(Xenopus tropicalis)
phospho-SAV1 [cytosol]
(Bos taurus)
phospho-SAV1 [cytosol]
(Canis familiaris)
phospho-SAV1 [cytosol]
(Gallus gallus)
phospho-SAV1 [cytosol]
(Sus scrofa)
phospho-zgc:92250 [cytosol]
(Danio rerio)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_068590.1
OpenTargets
ENSG00000151748
HPA
ENSG00000151748-SAV1
GeneCards
Q9H4B6
Ensembl
ENST00000324679
,
ENSG00000151748
,
ENSP00000324729
PRO
Q9H4B6
Pharos - Targets
Q9H4B6
PDB
6AO5
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13188 STK3
4
p-T180-STK3(1-322) [cytosol]
(R-HSA-2028696)
STK3(323-491) [cytosol]
(R-HSA-2028684)
STK3(1-491) [cytosol]
(R-HSA-2028280)
p-T180-STK3(1-491) [cytosol]
(R-HSA-2028274)
0.954
26
UniProt:Q13043 STK4
4
STK4(1-487) [cytosol]
(R-HSA-201627)
p-T183-STK4(1-326) [cytosol]
(R-HSA-2028682)
p-T183-STK4(1-487) [cytosol]
(R-HSA-2028258)
STK4(327-487) [cytosol]
(R-HSA-2028668)
0.937
20
UniProt:P49674 CSNK1E
2
CSNK1E [nucleoplasm]
(R-HSA-421306)
CSNK1E [cytosol]
(R-HSA-205877)
0.527
2
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