Reactome | AMOTL1 [cytosol]

AMOTL1 [cytosol]

Stable Identifier

R-HSA-2028603

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Angiomotin-like protein 1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8IY63 AMOTL1

Gene Names

AMOTL1

Chain

chain:1-956

Reference Genes

BioGPS Gene:154810 AMOTL1

COSMIC (genes):AMOTL1 AMOTL1

CTD Gene:154810 AMOTL1

dbSNP Gene:154810 AMOTL1

ENSEMBL:ENSG00000166025 AMOTL1

HGNC:17811 AMOTL1

KEGG:hsa:154810 AMOTL1

Monarch:154810 AMOTL1

NCBI Gene:154810 AMOTL1

OMIM:614657 AMOTL1

UCSC:Q8IY63 AMOTL1

Reference Transcript

Other Identifiers

11725704_a_at

11725705_a_at

11725706_s_at

11725707_a_at

154810

16730268

225450_PM_at

225450_at

225459_PM_at

225459_at

228840_PM_at

228840_at

235277_PM_at

235277_at

3345223

3345229

3345233

3345234

3345242

3345243

3345244

3345245

3345246

3345247

3345248

3345249

3345250

3345259

3345261

3345262

3345263

3345264

3345265

3345271

3345272

3345277

3345278

3345279

3345281

3345285

3345286

3345287

3345288

3345290

3345291

3345294

3345295

3345296

3345297

3345298

3345299

3345300

3345301

3345302

3345303

3345304

3345305

3345306

54841_at

65483_at

70606_at

7943263

90275_at

A_14_P107565

A_19_P00327669

A_23_P138796

A_24_P252823

A_24_P329815

A_24_P401768

A_33_P3271196

GE56673

GO:0001525

GO:0003365

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0005923

GO:0007010

GO:0007163

GO:0008180

GO:0016055

GO:0030036

GO:0030334

GO:0031410

GO:0035329

GO:0042802

GO:0043226

HMNXSV003025263

HMNXSV003025507

HMNXSV003044415

Hs.101550.0.A1_3p_at

Hs.17110.0.A1_3p_at

Hs.17110.0.A2_3p_at

Hs.208341.0.S1_3p_at

ILMN_1748141

PH_hs_0023547

PH_hs_0040755

TC11000924.hg

Participates

as a member of

AMOT proteins [cytosol] (Homo sapiens)

Inferred To

amotl1 [cytosol] (Xenopus tropicalis)

AMOTL1 [cytosol] (Bos taurus)

AMOTL1 [cytosol] (Canis familiaris)

AMOTL1 [cytosol] (Gallus gallus)

AMOTL1 [cytosol] (Sus scrofa)

Amotl1 [cytosol] (Mus musculus)

Amotl1 [cytosol] (Rattus norvegicus)

Homologues of AMOTL1 [cytosol] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000433060, ENST00000317829, ENSP00000387739, ENSG00000166025, ENSP00000320968

OpenTargets

ENSG00000166025

GeneCards

AMOTL1

HPA

ENSG00000166025-AMOTL1

PRO

Q8IY63

Pharos - Targets

Q8IY63

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.725	5
UniProt:P46937 YAP1	8	YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y407-YAP1 [cytosol] (R-HSA-9865208)	0.671	5
UniProt:Q8N3R9 MPP5	2	MPP5 [plasma membrane] (R-HSA-419969) MPP5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9689606)	0.527	3

© 2025 Reactome

Cite Us!