STK4(327-487) [cytosol]

Stable Identifier
R-HSA-2028668
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
STK4/C, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C
Locations in the PathwayBrowser for interactor UniProt:Q13188
Expand all
Literature References
PubMed ID Title Journal Year
9545236 Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

Graves, JD, Gotoh, Y, Draves, KE, Ambrose, DM, Han, DK, Wright, M, Chernoff, J, Clark, EA, Krebs, EG

EMBO J 1998
11278283 MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation

Lee, KK, Ohyama, T, Yajima, N, Tsubuki, S, Yonehara, S

J Biol Chem 2001
External Reference Information
External Reference
UniProt:Q13043 STK4
Gene Names
STK4, KRS2, MST1
Chain
chain:1-487, chain:1-326, chain:327-487
Reference Genes
BioGPS Gene:6789 STK4
COSMIC (genes):STK4 STK4
CTD Gene:6789 STK4
dbSNP Gene:6789 STK4
ENSEMBL:ENSG00000101109 STK4
HGNC:11408 STK4
KEGG Gene (Homo sapiens):6789 STK4
Monarch:6789 STK4
NCBI Gene:6789 STK4
OMIM:604965 STK4
UCSC:Q13043 STK4
Reference Transcript
Other Identifiers
0001090524
0106760021
11723400_a_at
11723401_x_at
11723402_a_at
11750551_a_at
11756934_a_at
16914147
205411_at
211085_s_at
225364_at
236259_at
36294_at
3886705
3886706
3886707
3886710
3886718
3886720
3886722
3886724
3886725
3886727
3886728
3886732
3886738
3886743
3886744
3886745
3886746
3886747
3886749
3886751
53858_at
59278_at
6789
77474_at
8062908
A_14_P120879
A_23_P143199
A_24_P185615
A_24_P94054
A_33_P3222648
GE511474
GE705798
GE81616
GE86072
GO:0000003
GO:0000166
GO:0000287
GO:0000902
GO:0001569
GO:0001841
GO:0001934
GO:0002376
GO:0003157
GO:0003674
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006464
GO:0006468
GO:0006915
GO:0006950
GO:0007155
GO:0007165
GO:0007267
GO:0007417
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0009790
GO:0016301
GO:0016310
GO:0016604
GO:0016740
GO:0018105
GO:0023014
GO:0030154
GO:0030216
GO:0030234
GO:0031098
GO:0032092
GO:0032147
GO:0032991
GO:0033138
GO:0035329
GO:0035556
GO:0040007
GO:0040011
GO:0042802
GO:0042803
GO:0043065
GO:0043167
GO:0043226
GO:0043539
GO:0045600
GO:0046621
GO:0046777
GO:0046872
GO:0048646
GO:0048856
GO:0048870
GO:0050821
GO:0060215
GO:0060706
GO:0060800
GO:0071902
GO:0090090
GO:0097284
GO:1902043
GO:1904237
GO:1905461
Hs.250824.0.S1_3p_at
Hs.268051.0.A1_3p_at
ILMN_1711383
PH_hs_0002864
TC20000339.hg
TC20001234.hg
U18297_s_at
g405738_3p_s_at
g5454095_3p_at
Participant Of
output
Other forms of this molecule
p-T183-STK4(1-326) [cytosol]
p-T183-STK4(1-487) [cytosol]
STK4(1-487) [cytosol]
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
IntEnz
HPA
GeneCards
Ensembl
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (29)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9H4B6 SAV1  2 0.94 20
 UniProt:P50749 RASF2      0.917 16
 UniProt:Q13188 STK3  4 0.903 18
 UniProt:Q8WWW0 RASF5      0.857 8
 UniProt:Q9NS23 RASF1      0.848 8
 UniProt:Q9H2L5 RASF4      0.788 6
 UniProt:Q86WH2 RASF3      0.779 6
 UniProt:Q9H8S9 MOB1A  2 0.753 9
 UniProt:Q14BN4 SLMAP      0.734 7
 UniProt:Q9NS23-2 RASSF1      0.729 4
 UniProt:Q13043 STK4  4 0.692 4
 UniProt:P46821 MAP1B      0.669 3
 UniProt:Q06830 PRDX1  3 0.66 11
 UniProt:Q66K74 MAP1S      0.643 4
 UniProt:Q7L9L4 MOB1B  2 0.642 4
 UniProt:Q6ZTQ3 RASF6      0.632 4
 UniProt:Q9GZQ8 MAP1LC3B  3 0.632 7
 UniProt:P31749 AKT1  13 0.619 13
 UniProt:P35700 Prdx1  3 0.611 3
 UniProt:Q8WWW0-2 RASSF5      0.581 4
 UniProt:Q99MK9 RASF1      0.564 2
 UniProt:P60520 GABARAPL2  3 0.544 2
 UniProt:O95166 GABARAP  3 0.544 2
 UniProt:Q9H0R8 GABARAPL1  3 0.544 2
 UniProt:P04083 ANXA1  2 0.527 2
 UniProt:O43815 STRN  3 0.527 3
 UniProt:Q91VJ4 STK38      0.525 2
 UniProt:Q8WWW0-3 RASSF5      0.508 2
 UniProt:Q9H492 MAP1LC3A  3 0.499 5
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