Reactome | SNAP25 [plasma membrane]

SNAP25 [plasma membrane]

Stable Identifier

R-HSA-2029017

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Synaptosomal-associated protein 25

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P60880 SNAP25

Gene Names

SNAP25, SNAP

Chain

chain:1-206

Reference Genes

BioGPS Gene:6616 SNAP25

COSMIC (genes):SNAP25 SNAP25

CTD Gene:6616 SNAP25

dbSNP Gene:6616 SNAP25

ENSEMBL:ENSG00000132639 SNAP25

HGNC:11132 SNAP25

KEGG Gene (Homo sapiens):6616 SNAP25

Monarch:6616 SNAP25

NCBI Gene:6616 SNAP25

OMIM:600322 SNAP25

UCSC:P60880 SNAP25

Reference Transcript

Other Identifiers

0001580102

11733726_a_at

11733727_s_at

11750076_a_at

11750077_x_at

16911418

1830

1KIL

1XTG

202507_s_at

202508_s_at

2N1T

360

38484_at

3876244

3876246

3876247

3876258

3876259

3876262

3876265

3876271

3876272

3876279

3876280

3876282

3876283

3876288

3876289

3DDA

3DDB

3RK2

3RK3

3RL0

3ZUR

5W7I

5W7J

6616

8060963

A0A0A0MSS0

A_23_P210756

A_33_P3338693

AAC37545

AAC37546

AAH10647

AAV38490

AK223617

AK289647

AK314359

AL023913

BAA22370

BAD97337

BAF82336

BAG36991

BC010647

BT019684

CAB000360

CCDS13109

CCDS13110

CH471133

D21267

D21267_at

EAX10346

EAX10349

EAX10350

EAX10352

ENSG00000132639

ENSP00000254976

ENSP00000307341

ENST00000254976

ENST00000254976.6

ENST00000304886

ENST00000304886.6

EntrezGene:6616

EntrezGene:SNAP25

g307425_3p_a_at

g4507098_3p_a_at

GE61378

GO:0000149

GO:0001504

GO:0002376

GO:0003674

GO:0005249

GO:0005484

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005794

GO:0005802

GO:0005829

GO:0005856

GO:0005886

GO:0006810

GO:0006887

GO:0006906

GO:0007267

GO:0007268

GO:0007269

GO:0007626

GO:0008021

GO:0008076

GO:0008150

GO:0008306

GO:0010975

GO:0014047

GO:0015031

GO:0016020

GO:0016079

GO:0016081

GO:0016082

GO:0016192

GO:0017075

GO:0019905

GO:0022607

GO:0022857

GO:0030054

GO:0030154

GO:0030424

GO:0030426

GO:0031083

GO:0031201

GO:0031234

GO:0031410

GO:0031629

GO:0031982

GO:0032991

GO:0035579

GO:0036477

GO:0042734

GO:0043005

GO:0043226

GO:0043312

GO:0045202

GO:0048306

GO:0048471

GO:0048856

GO:0050796

GO:0050877

GO:0055085

GO:0060291

GO:0061024

GO:0065003

GO:0070032

GO:0070201

GO:0070821

GO:0071805

GO:0098794

GO:0098967

GO:0098978

GO:0099590

HGNC:11132

HPA001830

ILMN_1740555

ILMN_2408080

IPR000727

IPR000928

IPR039077

L19760

L19761

MIM:600322

MIM:616330

NM_001322902

NM_001322903

NM_001322904

NM_001322905

NM_001322906

NM_001322907

NM_001322908

NM_001322909

NM_001322910

NM_003081

NM_130811

NP_001309831

NP_001309832

NP_001309833

NP_001309834

NP_001309835

NP_001309836

NP_001309837

NP_001309838

NP_001309839

NP_003072

NP_570824

PF00835

PH_hs_0023120

SM00397

SNAP25

SNAP25-201

SNAP25-202

TC20000082.hg

UPI0000001103

UPI000002B3DD

XM_005260808

XM_017028021

XM_017028022

XP_005260865

XP_016883510

XP_016883511

Participant Of

hasComponent

input

hasMember

Other forms of this molecule

SNAP25(1-197) [plasma membrane]

SNAP25(198-206) [cytosol]

SNAP25(1-198) [plasma membrane]

SNAP25(199-206) [cytosol]

SNAP25 [tertiary granule membrane]

SNAP25 [specific granule membrane]

Inferred To

SNAP25 [plasma membrane] (Bos taurus)

SNAP25 [plasma membrane] (Caenorhabditis elegans)

SNAP25 [plasma membrane] (Canis familiaris)

SNAP25 [plasma membrane] (Danio rerio)

SNAP25 [plasma membrane] (Dictyostelium discoideum)

SNAP25 [plasma membrane] (Drosophila melanogaster)

SNAP25 [plasma membrane] (Gallus gallus)

SNAP25 [plasma membrane] (Mus musculus)

SNAP25 [plasma membrane] (Plasmodium falciparum)

SNAP25 [plasma membrane] (Rattus norvegicus)

SNAP25 [plasma membrane] (Saccharomyces cerevisiae)

SNAP25 [plasma membrane] (Schizosaccharomyces pombe)

SNAP25 [plasma membrane] (Sus scrofa)

SNAP25 [plasma membrane] (Xenopus tropicalis)

Homologues of SNAP25 [plasma membrane] (Caenorhabditis elegans)

Homologues of SNAP25 [plasma membrane] (Dictyostelium discoideum)

Homologues of SNAP25 [plasma membrane] (Drosophila melanogaster)

Homologues of SNAP25 [plasma membrane] (Saccharomyces cerevisiae)

Modified Residues

Name

S-palmitoyl-L-cysteine at 85

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Name

S-palmitoyl-L-cysteine at 88

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Name

S-palmitoyl-L-cysteine at 90

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Name

S-palmitoyl-L-cysteine at 92

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Cross References

RefSeq

NP_001309836.1, NP_001309832.1, XP_016883511.1, NP_001309837.1, XP_016883510.1, NP_001309833.1, NP_001309834.1, NP_001309838.1, NP_003072.2, NP_001309839.1, NP_570824.1, NP_001309831.1, NP_001309835.1, XP_005260865.1

OpenTargets

ENSG00000132639

GeneCards

P60880

PRO

P60880

Orphanet

23214

HMDB Protein

HMDBP02940

PDB

2N1T, 1KIL, 3ZUR, 3RK2, 3RK3, 1XTG, 3RL0, 5W7I, 3DDA, 5W7J, 3DDB

Interactors (3)

Accession	Confidence Score	Evidence (IntAct)
UniProt:O75558 STX11	0.553	2
UniProt:Q8IUH5 ZDH17	0.489	3
UniProt:Q9Y3C0 WASC3	0.488	2