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ARF6 [recycling endosome membrane]
Stable Identifier
R-HSA-2029049
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
recycling endosome membrane
Synonyms
ADP-ribosylation factor 6, ARF6_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
MET receptor recycling (Homo sapiens)
GGA3 associates with activated MET receptor (Homo sapiens)
ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6 [recycling endosome membrane] (Homo sapiens)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6 [recycling endosome membrane] (Homo sapiens)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Homo sapiens)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6 [recycling endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
TBC/RABGAPs (Homo sapiens)
TBC1D10A (EPI64) binds ARF6:GTP (Homo sapiens)
ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6 [recycling endosome membrane] (Homo sapiens)
TBC1D10A:ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6:GTP [recycling endosome membrane] (Homo sapiens)
ARF6 [recycling endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62330 ARF6
Gene Names
ARF6
Chain
initiator methionine:1, chain:2-175
Reference Genes
BioGPS Gene:382 ARF6
COSMIC (genes):ARF6 ARF6
CTD Gene:382 ARF6
dbSNP Gene:382 ARF6
ENSEMBL:ENSG00000165527 ARF6
HGNC:659 ARF6
KEGG Gene (Homo sapiens):382 ARF6
Monarch:382 ARF6
NCBI Gene:382 ARF6
OMIM:600464 ARF6
UCSC:P62330 ARF6
Reference Transcript
RefSeq:NM_001663.3 ARF6
Other Identifiers
11717401_at
11717402_s_at
11758273_s_at
16783974
1E0S
203311_s_at
203312_x_at
224788_at
2631342
2778
2A5D
2A5F
2A5G
2BAO
2BAU
2J5X
2W83
3063398
3063399
33152_at
3535001
3535004
3535005
3535006
3535007
3535008
3535009
3535010
382
3LVQ
3LVR
3N5C
3PCR
43480_at
4FME
4KAX
54829_s_at
54831_r_at
6BBP
6BBQ
7974249
A_14_P107803
A_23_P48691
A_24_P472455
AAA90928
AAC39877
AAH08918
AAM12599
AAP50257
AF047432
AF493885
AK313790
ARF6
ARF6-201
AY296206
BAG36527
BC002952
BC008918
CAB002778
CAG46762
CCDS9695
CH471078
CR541964
EAW65740
ENSG00000165527
ENSP00000298316
ENST00000298316
ENST00000298316.6
EntrezGene:382
EntrezGene:ARF6
g178988_3p_a_at
g6996000_3p_a_at
GE58261
GO:0000166
GO:0001726
GO:0001889
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005768
GO:0005769
GO:0005794
GO:0005829
GO:0005886
GO:0005925
GO:0005938
GO:0006810
GO:0006886
GO:0007010
GO:0007049
GO:0007155
GO:0007165
GO:0007399
GO:0008150
GO:0008219
GO:0010008
GO:0010975
GO:0015031
GO:0016020
GO:0016192
GO:0019899
GO:0022607
GO:0030139
GO:0030154
GO:0030838
GO:0030866
GO:0031410
GO:0031527
GO:0031901
GO:0031996
GO:0032154
GO:0032456
GO:0033028
GO:0034330
GO:0034394
GO:0035020
GO:0036010
GO:0040011
GO:0042995
GO:0043167
GO:0043226
GO:0047485
GO:0048261
GO:0048488
GO:0048856
GO:0048870
GO:0050714
GO:0051301
GO:0051489
GO:0051549
GO:0055037
GO:0055038
GO:0060998
GO:0065003
GO:0070062
GO:0090073
GO:0090162
GO:0090543
GO:0097178
GO:0097284
GO:0098793
GO:0098978
GO:0099562
GO:1903078
GO:1903393
GO:1905606
GO:1990090
GO:2000009
GO:2000171
HGNC:659
Hs.180777.0.A1_3p_at
IPR005225
IPR006689
IPR027417
IPR041838
M57763
M57763_at
MIM:600464
NM_001663
NP_001654
PF00025
PR00328
SM00175
SM00177
SM00178
TC14000280.hg
TC14001678.hg
UPI0000021AA1
Participant Of
hasComponent
ARF6:GTP [recycling endosome membrane]
Other forms of this molecule
ARF6 [cytosol]
Inferred To
ARF6 [recycling endosome membrane] (Bos taurus)
ARF6 [recycling endosome membrane] (Caenorhabditis elegans)
ARF6 [recycling endosome membrane] (Canis familiaris)
ARF6 [recycling endosome membrane] (Danio rerio)
ARF6 [recycling endosome membrane] (Dictyostelium discoideum)
ARF6 [recycling endosome membrane] (Drosophila melanogaster)
ARF6 [recycling endosome membrane] (Mus musculus)
ARF6 [recycling endosome membrane] (Rattus norvegicus)
ARF6 [recycling endosome membrane] (Saccharomyces cerevisiae)
ARF6 [recycling endosome membrane] (Schizosaccharomyces pombe)
ARF6 [recycling endosome membrane] (Sus scrofa)
ARF6 [recycling endosome membrane] (Xenopus tropicalis)
Ghost homologue of ARF6 [recycling endosome membrane] (Gallus gallus)
Cross References
RefSeq
NP_001654.1
OpenTargets
ENSG00000165527
GeneCards
P62330
PRO
P62330
HMDB Protein
HMDBP08304
PDB
3LVQ
,
2BAU
,
2A5G
,
4KAX
,
3LVR
,
2W83
,
3N5C
,
2A5F
,
4FME
,
2BAO
,
6BBQ
,
1E0S
,
3PCR
,
2A5D
,
2J5X
,
6BBP
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q02241 KIF23
3
p-S904,S905-KIF23 [nucleoplasm]
(R-HSA-156695)
KIF23 [cytosol]
(R-HSA-1015863)
KIF23 [nucleoplasm]
(R-HSA-156709)
0.667
23
UniProt:O00213 APBB1
1
APBB1 [nucleoplasm]
(R-HSA-5683987)
0.633
9
UniProt:O60271 SPAG9
1
SPAG9 [cytosol]
(R-HSA-375975)
0.618
8
UniProt:Q9NZ52 GGA3
3
GGA3 [recycling endosome membrane]
(R-HSA-8875655)
GGA3 [endosome membrane]
(R-HSA-5692936)
GGA3 [early endosome membrane]
(R-HSA-8854137)
0.589
3
UniProt:P53365 ARFIP2
1
ARFIP2 [cytosol]
(R-HSA-6813848)
0.57
4
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