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DBNL(362-431) [cytosol]
Stable Identifier
R-HSA-202933
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
HIP-55 fragment (362-431)
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptotic cleavage of cellular proteins (Homo sapiens)
Caspase-mediated cleavage of cytoskeletal proteins (Homo sapiens)
Caspase mediated cleavage of HIP-55 (Homo sapiens)
DBNL(362-431) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UJU6 DBNL
Gene Names
DBNL, CMAP, SH3P7, PP5423
Chain
chain:1-430
Reference Genes
BioGPS Gene:28988 DBNL
COSMIC (genes):DBNL DBNL
CTD Gene:28988 DBNL
dbSNP Gene:28988 DBNL
ENSEMBL:ENSG00000136279 DBNL
ENSEMBL_homo_sapiens_GENE:ENSG00000136279.21 DBNL
HGNC:2696 DBNL
KEGG Gene (Homo sapiens):28988 DBNL
Monarch:28988 DBNL
NCBI Gene:28988 DBNL
OMIM:610106 DBNL
UCSC:Q9UJU6 DBNL
Reference Transcript
RefSeq:NM_001284313.1 DBNL
RefSeq:NM_001014436.2 DBNL
RefSeq:NM_001284315.1 DBNL
RefSeq:NM_014063.6 DBNL
RefSeq:NM_001122956.1 DBNL
Other Identifiers
11740992_x_at
11747076_a_at
11748558_a_at
11748559_x_at
11750282_x_at
11756792_x_at
11757879_s_at
17045599
222429_PM_at
222429_at
28988
2999711
2999712
2999715
2999717
2999718
2999719
2999721
2999724
2999725
2999727
2999728
2999729
2999730
2999731
2999732
2999733
2999734
2999736
2999738
2999740
2999742
2999743
2999744
2999745
2999746
2999747
2999748
2999749
2999750
2999751
2999752
2999754
48577_at
67173_at
8132539
88842_r_at
A_14_P134457
A_14_P134641
A_23_P168692
A_24_P43681
A_33_P3211260
A_33_P3295009
GE479780
GE81857
GE86253
GE86342
GO:0000139
GO:0001726
GO:0002102
GO:0002250
GO:0002376
GO:0003779
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0005769
GO:0005794
GO:0005829
GO:0005856
GO:0005886
GO:0005938
GO:0006897
GO:0007010
GO:0007416
GO:0008047
GO:0008092
GO:0014069
GO:0016020
GO:0016192
GO:0016601
GO:0019904
GO:0023052
GO:0030027
GO:0030154
GO:0030425
GO:0030665
GO:0031410
GO:0034330
GO:0034774
GO:0042995
GO:0043005
GO:0043204
GO:0043226
GO:0043231
GO:0045202
GO:0045296
GO:0048812
GO:0048856
GO:0051015
GO:0061024
GO:0065003
GO:0070062
GO:0070161
GO:0071800
GO:0098772
GO:0098793
GO:0098794
GO:0098973
GO:0098974
GO:0098978
GO:1904724
GO:1904813
HMNXSV003020595
HMNXSV003022481
HMNXSV003037724
ILMN_1698307
ILMN_2376289
PH_hs_0010817
TC07003393.hg
g8885629_3p_at
p29474
Participates
as an output of
Caspase mediated cleavage of HIP-55 (Homo sapiens)
Other forms of this molecule
DBNL [secretory granule lumen]
DBNL [ficolin-1-rich granule lumen]
DBNL [cytosol]
DBNL(1-361) [cytosol]
DBNL [tertiary granule lumen]
DBNL [extracellular region]
Inferred To
CAP [cytosol]
(Drosophila melanogaster)
Homologues of DBNL(362-431) [cytosol]
(Caenorhabditis elegans)
Homologues of DBNL(362-431) [cytosol]
(Dictyostelium discoideum)
SORBS2 [cytosol]
(Bos taurus)
SORBS2 [cytosol]
(Canis familiaris)
SORBS2 [cytosol]
(Sus scrofa)
Sorbs2 [cytosol]
(Mus musculus)
Sorbs2 [cytosol]
(Rattus norvegicus)
sorb-1 [cytosol]
(Caenorhabditis elegans)
DBNL(362-431) [cytosol]
(Caenorhabditis elegans)
DBNL(362-431) [cytosol]
(Dictyostelium discoideum)
DBNL(362-431) [cytosol]
(Gallus gallus)
PIN3 [cytosol]
(Saccharomyces cerevisiae)
sfp47 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001014436.1
,
NP_054782.2
,
NP_001271244.1
,
NP_001271242.1
,
NP_001116428.1
OpenTargets
ENSG00000136279
GeneCards
Q9UJU6
HPA
ENSG00000136279-DBNL
Ensembl
ENSP00000415173
,
ENSP00000419992
,
ENST00000494774
,
ENST00000490734
,
ENST00000448521
,
ENST00000468694
,
ENSP00000416421
,
ENSP00000417653
,
ENST00000440166
,
ENST00000456905
,
ENSP00000411701
,
ENSP00000417749
,
ENSG00000136279
PRO
Q9UJU6
Pharos - Targets
Q9UJU6
PDB
1X67
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H788 SH24A
0.764
6
UniProt:P78314 3BP2
0.659
7
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
11
UniProt:Q96JN8 NEUL4
0.564
3
UniProt:O95714 HERC2
5
HERC2 [nucleoplasm]
(R-HSA-4551680)
p-T4827-HERC2 [nucleoplasm]
(R-HSA-5682601)
p-T4827,SUMO1-HERC2 [nucleoplasm]
(R-HSA-5682615)
HERC2 [cytosol]
(R-HSA-975975)
monoSUMO1-HERC2 [nucleoplasm]
(R-HSA-4551758)
0.564
3
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:P22607 FGFR3
20
FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane]
(R-HSA-8853144)
FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]
(R-HSA-8853131)
FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane]
(R-HSA-8853152)
FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane]
(R-HSA-8853124)
FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane]
(R-HSA-8853125)
FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
(R-HSA-8853127)
FGFR3 K650T [plasma membrane]
(R-HSA-1614411)
FGFR3 K650N [plasma membrane]
(R-HSA-1614406)
FGFR3 K650M [plasma membrane]
(R-HSA-1614402)
FGFR3 K650Q [plasma membrane]
(R-HSA-1614410)
FGFR3 A391E [plasma membrane]
(R-HSA-1614390)
FGFR3 K650E [plasma membrane]
(R-HSA-1614400)
FGFR3 G380R [plasma membrane]
(R-HSA-1614398)
FGFR3 G382D [plasma membrane]
(R-HSA-2018740)
FGFR3 805fs*141 [plasma membrane]
(R-HSA-1614387)
FGFR3 [plasma membrane]
(R-HSA-2038357)
FGFR3 S371C [plasma membrane]
(R-HSA-1614421)
FGFR3 Y373C [plasma membrane]
(R-HSA-1614424)
FGFR3 G370C [plasma membrane]
(R-HSA-1614394)
FGFR3 R248C [plasma membrane]
(R-HSA-1614419)
0.556
3
UniProt:P06396 GSN
7
GSN(200-270) [extracellular region]
(R-HSA-976940)
GSN [secretory granule lumen]
(R-HSA-6801486)
GSN [extracellular region]
(R-HSA-6806510)
GSN [ficolin-1-rich granule lumen]
(R-HSA-6801465)
GSN(404-782) [cytosol]
(R-HSA-350272)
GSN(28-403) [cytosol]
(R-HSA-201618)
GSN [cytosol]
(R-HSA-350275)
0.556
3
UniProt:Q9H788-2 SH2D4A
0.556
3
UniProt:Q14957 GRIN2C
3
GRIN2C [plasma membrane]
(R-HSA-419560)
p-Y-GRIN2C [plasma membrane]
(R-HSA-9612189)
GRIN2C [endoplasmic reticulum membrane]
(R-HSA-9609761)
0.556
3
UniProt:P46379-2 BAG6
0.556
3
UniProt:O14645 IDLC
0.556
3
UniProt:O14901 KLF11
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q96AP0 ACD
1
ACD [nucleoplasm]
(R-HSA-174889)
0.508
2
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.483
2
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