p-8Y-FGFR2 [plasma membrane]

Stable Identifier
R-HSA-2029874
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
phosphorylated FGFR2
p-8Y-FGFR2 [plasma membrane] icon
Locations in the PathwayBrowser
General
This represents WT FGFR2 of either the IIIb or IIIc isoform that is found overexpressed in some cancers. Sites of tyrosine phosphorylation are marked as unknown to circumvent the numbering differences between the isoform variants.
External Reference Information
External Reference
Gene Names
FGFR2, BEK, KGFR, KSAM
Chain
signal peptide:1-21, chain:22-821
Participates
Other forms of this molecule
Modified Residues
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Interactors (30)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.779 5
 UniProt:P51812 RPS6KA3  7 0.745 5
 UniProt:P62993 GRB2  1 0.735 6
 ChEBI:73280 SSR      0.683 8
 UniProt:P05230 FGF1  1 0.675 3
 UniProt:P11362 FGFR1  9 0.623 3
 UniProt:O15520 FGF10  1 0.571 2
 UniProt:P19174 PLCG1  6 0.528 3
 UniProt:Q3MIR4 CC50B      0.527 2
 UniProt:O60637 TSN3      0.527 2
 UniProt:Q96LL9 DJC30      0.527 2
 UniProt:Q6P047 CH074      0.527 2
 UniProt:Q99732 LITAF      0.527 2
 UniProt:Q8N7X8 SIGL1      0.527 2
 UniProt:Q5T9A4 ATAD3B  3 0.527 2
 UniProt:Q96HB5 CC120      0.527 2
 UniProt:Q8IWX8 CHERP  1 0.527 2
 UniProt:Q92551 IP6K1  2 0.527 2
 UniProt:Q6P995 F171B      0.527 2
 UniProt:P34741 SDC2  20 0.527 2
 UniProt:Q92575 UBXN4      0.527 2
 UniProt:Q96L94 SNX22      0.527 2
 UniProt:P01033 TIMP1  4 0.527 2
 UniProt:Q96G30 MRAP2      0.527 2
 UniProt:P55899 FCGRN      0.527 2
 UniProt:Q5TF58 IFFO2      0.527 2
 UniProt:Q06124 PTPN11  4 0.519 2
 UniProt:Q9ULH0 KIDINS220  2 0.483 2
 UniProt:Q9UBH6 S53A1      0.483 2
 UniProt:Q86VI4 LAP4B      0.463 2
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