FGFR2 W290C mutant dimer [plasma membrane]

Stable Identifier
R-HSA-2029919
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
17344846 Patterns of somatic mutation in human cancer genomes

Easton, DF, Dicks, E, Stratton, MR, Davies, H, Louis, DN, Tofts, C, Teh, BT, Edkins, S, Teague, J, Futreal, PA, Forbes, S, Vastrik, I, Varian, J, Wooster, R, Birney, E, Gray, K, Jones, D, Hinton, J, Hunter, C, Schmidt, EE, Yates, A, Greenman, C, Halliday, K, Yuen, ST, Hills, K, O'Meara, S, Khoo, SK, Green, AR, Jenkinson, A, Greaves, MF, Perry, J, Menzies, A, DeFazio, A, Nicholson, AG, Clements, J, Dalgliesh, GL, Chiew, YE, Choudhury, B, Chenevix-Trench, G, Harrison, R, Campbell, P, Cahill, DP, Leung, SY, Bhamra, G, Butler, A, Stephens, P, Stevens, C, Cole, J, Small, A, Brasseur, F, Smith, R, Buck, G, Raine, K, Barthorpe, S, Shepherd, R, Bignell, G, Webb, T, Tan, MH, Mironenko, T, Richardson, D, Avis, T, Looijenga, L, Weber, BL, West, S, Widaa, S, Goldstraw, P

Nature 2007
16140923 Somatic mutations of the protein kinase gene family in human lung cancer

Easton, DF, Dicks, E, Stratton, MR, Davies, H, Cooper, CS, Tofts, C, Teh, BT, Edkins, S, Teague, J, Pierotti, MA, Futreal, PA, Webb, A, Forbes, S, Flanagan, AM, Kosmidou, V, Lakhani, SR, Laman, R, Jones, D, Knowles, M, Hinton, J, Hunter, C, Yates, A, Greenman, C, Halliday, K, Yuen, ST, Hills, K, O'Meara, S, Perry, J, Malkowicz, B, Menzies, A, Parker, A, Nicholson, AG, Clements, J, Edwards, K, Green, A, Looijenga, LH, Harrison, R, Lugg, R, Leung, SY, Butler, A, Stephens, P, Stephens, Y, Stevens, C, Cole, J, Brackenbury, L, Small, A, Brasseur, F, Smith, R, Buck, G, Solomon, H, Raine, K, Barthorpe, S, Shepherd, R, Bignell, G, Petty, R, Avis, T, Weber, BL, West, S, Widaa, S, Goldstraw, P, Gorton, M, Gray, K, Wooster, R, Varian, J

Cancer Res 2005
18552176 Drug-sensitive FGFR2 mutations in endometrial carcinoma

Akslen, LA, Cibulskis, K, Greulich, H, Dutt, A, Sellers, WR, Chen, TH, Winckler, W, Wyhs, N, Ziaugra, L, Zody, MC, Salvesen, HB, Meyerson, M, Stefansson, IM, Trovik, J, Wong, KK, Ramos, AH, Richter, DJ, Gabriel, S, Nicoletti, R, Onofrio, RC, Grewal, R, Hanna, M, Hatton, C, Engelsen, IB, Fennell, T

Proc Natl Acad Sci U S A 2008
Participants
Participates
Disease
Name Identifier Synonyms
lung cancer DOID:1324
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
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