Association of profilin with monomeric actin

Stable Identifier
R-HSA-203070
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Profilins PFN1 and PFN2 bind to monomeric actin (G-actin), forming a 1:1 complex and subsequently regulate actin filament barbed end assembly downstream of various signaling pathways (Pring et al. 1992, Korenbaum et al. 1998, Nodelman et al. 1999)

Participants
Participant Of
Orthologous Events