eNOS translocation from Golgi to Caveolae

Stable Identifier
R-HSA-203700
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Golgi membrane, cytosol, plasma membrane
ReviewStatus
5/5
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eNOS translocation from Golgi to Caveolae
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Palymitoylated, myristoylated eNOS forms a dimer and is transported from the Golgi to the plasma membrane. Transport is thought to be mediated by intracellular vesicles, but the details remain unknown (Govers & Rabelink 2001; Oess et al. 2006).
Literature References
PubMed ID Title Journal Year
11208594 Cellular regulation of endothelial nitric oxide synthase

Rabelink, TJ, Govers, R

Am J Physiol Renal Physiol 2001
16722822 Subcellular targeting and trafficking of nitric oxide synthases

Muller-Esterl, W, Fulton, D, Oess, S, Govers, R, Icking, A

Biochem J 2006
Participants
Input
Output
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as an event of
Event Information
Go Biological Process
Golgi to plasma membrane protein transport (0043001)
Orthologous Events
eNOS translocation from Golgi to Caveolae (Bos taurus)
eNOS translocation from Golgi to Caveolae (Dictyostelium discoideum)
eNOS translocation from Golgi to Caveolae (Drosophila melanogaster)
eNOS translocation from Golgi to Caveolae (Gallus gallus)
eNOS translocation from Golgi to Caveolae (Mus musculus)
eNOS translocation from Golgi to Caveolae (Plasmodium falciparum)
eNOS translocation from Golgi to Caveolae (Rattus norvegicus)
eNOS translocation from Golgi to Caveolae (Saccharomyces cerevisiae)
eNOS translocation from Golgi to Caveolae (Schizosaccharomyces pombe)
eNOS translocation from Golgi to Caveolae (Sus scrofa)
Reviewed
Enikolopov, G  (2008-02-28)
Created
Hemish, J  (2007-11-15)
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