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SEC24D [ER to Golgi transport vesicle membrane]
Stable Identifier
R-HSA-204020
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ER to Golgi transport vesicle membrane
Synonyms
Protein transport protein Sec24D, S24D_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Budding of COPII coated vesicle (Homo sapiens)
COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Disassembly of COPII coated vesicle (Homo sapiens)
COPII [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC23:SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
SEC24D [ER to Golgi transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94855 SEC24D
Gene Names
SEC24D, KIAA0755
Chain
chain:1-1032
Reference Genes
BioGPS Gene:9871 SEC24D
COSMIC (genes):SEC24D SEC24D
CTD Gene:9871 SEC24D
dbSNP Gene:9871 SEC24D
ENSEMBL:ENSG00000150961 SEC24D
ENSEMBL_homo_sapiens_GENE:ENSG00000150961.15 SEC24D
HGNC:10706 SEC24D
KEGG Gene (Homo sapiens):9871 SEC24D
Monarch:9871 SEC24D
NCBI Gene:9871 SEC24D
OMIM:607186 SEC24D
UCSC:O94855 SEC24D
Reference Transcript
RefSeq:XM_005263379.2 SEC24D
RefSeq:NM_001318066.1 SEC24D
RefSeq:NM_014822.3 SEC24D
Other Identifiers
11717319_a_at
11746083_a_at
16979256
202375_PM_at
202375_at
2783317
2783318
2783325
2783328
2783329
2783336
2783338
2783340
2783341
2783343
2783344
2783345
2783347
2783349
2783352
2783355
2783356
2783364
2783365
2783367
2783368
2783369
2783375
2783380
2783383
2783384
2783385
2783386
32770_at
69085_s_at
8102482
9871
A_23_P159382
GE53464
GO:0000149
GO:0001701
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0006886
GO:0006888
GO:0008270
GO:0012507
GO:0015031
GO:0016020
GO:0016192
GO:0030127
GO:0031410
GO:0043226
GO:0043231
GO:0046872
GO:0048856
GO:0061024
GO:0070971
GO:0090110
HMNXSV003038254
ILMN_1656386
PH_hs_0024795
TC04001496.hg
g7662658_3p_at
Participates
as a member of
SEC24 [ER to Golgi transport vesicle membrane] (Homo sapiens)
Other forms of this molecule
p-SEC24D [cytosol]
SEC24D [cytosol]
SEC24D [endoplasmic reticulum membrane]
Inferred To
sec24d [ER to Golgi transport vesicle membrane]
(Xenopus tropicalis)
sec24l [ER to Golgi transport vesicle membrane]
(Dictyostelium discoideum)
Sec24CD [ER to Golgi transport vesicle membrane]
(Drosophila melanogaster)
SEC24D [ER to Golgi transport vesicle membrane]
(Bos taurus)
SEC24D [ER to Golgi transport vesicle membrane]
(Canis familiaris)
SEC24D [ER to Golgi transport vesicle membrane]
(Gallus gallus)
SEC24D [ER to Golgi transport vesicle membrane]
(Plasmodium falciparum)
SEC24D [ER to Golgi transport vesicle membrane]
(Schizosaccharomyces pombe)
SEC24D [ER to Golgi transport vesicle membrane]
(Sus scrofa)
SFB3 [ER to Golgi transport vesicle membrane]
(Saccharomyces cerevisiae)
sec-24.1 [ER to Golgi transport vesicle membrane]
(Caenorhabditis elegans)
Sec24d [ER to Golgi transport vesicle membrane]
(Mus musculus)
Sec24d [ER to Golgi transport vesicle membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_055637.2
,
XP_005263436.1
,
NP_001304995.1
OpenTargets
ENSG00000150961
HPA
ENSG00000150961-SEC24D
GeneCards
O94855
Ensembl
ENST00000280551
,
ENSP00000280551
,
ENSG00000150961
PRO
O94855
Pharos - Targets
O94855
Orphanet
23212
PDB
5KYY
,
5KYU
,
5KYX
,
3EFO
,
3EG9
,
5KYW
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