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BSG (basigin) binds Integrin alpha3beta1, alpha6beta1
Stable Identifier
R-HSA-204434
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Basigin binds to integrins
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Homo sapiens)
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
Basigin interactions (Homo sapiens)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Homo sapiens)
General
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SBGN
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Basigin is a widely distributed cell-surface protein with two immunoglobulin domains and has shown to associate with both the integrins alpha3beta1 and alpha6beta1.
Literature References
PubMed ID
Title
Journal
Year
9360995
Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6.
Bodorova, J
,
Hemler, ME
,
Berditchevski, F
,
Chang, S
J Biol Chem
1997
Participants
Input
BSG [plasma membrane]
(Homo sapiens)
Integrin alpha3beta1, alpha6beta1 [plasma membrane]
(Homo sapiens)
Output
BSG:Integrin alpha3beta1, alpha6beta1 [plasma membrane]
(Homo sapiens)
Participates
as an event of
Basigin interactions (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Orthologous Events
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Bos taurus)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Caenorhabditis elegans)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Canis familiaris)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Drosophila melanogaster)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Gallus gallus)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Mus musculus)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Rattus norvegicus)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Sus scrofa)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Xenopus tropicalis)
Authored
Geiger, B (2008-05-07)
Horwitz, AR (2008-05-07)
Reviewed
Humphries, MJ (2008-05-07)
Yamada, KM (2008-05-07)
Hynes, R (2008-05-07)
Created
de Bono, B (2007-11-28)
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