Reactome: A Curated Pathway Database

Basigin binds CyPA

Stable Identifier
R-HSA-204485
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cyclophilin A (CyPA)1 is an intracellular protein belonging to the immunophilin family and is recognized as the major target for the potent immunosuppressive drug cyclosporin A. CD147 is the natural cell surface receptor for CyPA. It is demonstrated that CD147 is an essential component in the CyPA-initiated signaling cascade that culminates in ERK activation.

Literature References
Participants
Participant Of
This entity is regulated by:
Orthologous Events