Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA

Stable Identifier
R-HSA-2046095
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Docosatetraenoyl-CoA is elongated to tetracosatetraenoyl-CoA (TTA-CoA, 9,12,15,18-tetracosatetraenoic acid, 9,12,15,18-24:4(n-6)) by the elongase enzyme ELOVL2.

Literature References
PubMed ID Title Journal Year
14636670 Elongation of long-chain fatty acids

Leonard, AE, Pereira, SL, Sprecher, H, Huang, YS

Prog Lipid Res 2004
9704073 Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles

Ayala, S, Gaspar, G, Brenner, RR, Peluffo, RO, Kunau, W

J Lipid Res 1973
5411545 The biosynthesis of delta-9,12,15,18-tetracosatetraenoic and of delta-6,9,12,15,18-tetracosapentaenoic acids by rat testes

Bridges, RB, Coniglio, JG

J Biol Chem 1970
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
fatty acid elongase activity of ELOVL2 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created