Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA

Stable Identifier
R-HSA-2046097
Type
Reaction
Species
Homo sapiens
Compartment
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Tetracosatetraenoyl-CoA is further desaturated by delta 6-desaturase (FADS2) to tetracosapentaenoyl-CoA (TPA-CoA, 6,9,12,15,18-24:5(n-6)).

Literature References
PubMed ID Title Journal Year
11988075 The same rat Delta6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis

d'Andréa, S, Guillou, H, Jan, S, Catheline, D, Thibault, JN, Bouriel, M, Rioux, V, Legrand, P

Biochem J 2002
1834642 The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase

Voss, A, Reinhart, M, Sankarappa, S, Sprecher, H

J Biol Chem 1991
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
linoleoyl-CoA desaturase activity of FADS2 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
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Created
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