Further sulfation on galactose residues produces KSPG

Stable Identifier
R-HSA-2046175
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane, Golgi lumen
ReviewStatus
5/5
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Further sulfation on galactose residues produces KSPG
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Carbohydrate sulfotransferase 1 (CHST1, keratan sulfate Gal-6 sulfotransferase) mediates the sulfation of galactose (Gal) on position 6 in keratan sulfate proteoglycans (KSPGs) (Fukuta et al. 1997).
Literature References
PubMed ID Title Journal Year
9405439 Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase

Habuchi, O, Torii, T, Shimada, E, Tsuzuki, K, Inazawa, J, Fukuta, M

J Biol Chem 1997
Participants
Input
Output
Participates
as an event of
Catalyst Activity

keratan sulfotransferase activity of CHST1 [Golgi membrane]

Physical Entity
CHST1 [Golgi membrane] (Homo sapiens)
Activity
keratan sulfotransferase activity (GO:0045130)
Orthologous Events
Further sulfation on galactose residues produces KSPG (Bos taurus)
Further sulfation on galactose residues produces KSPG (Canis familiaris)
Further sulfation on galactose residues produces KSPG (Danio rerio)
Further sulfation on galactose residues produces KSPG (Drosophila melanogaster)
Further sulfation on galactose residues produces KSPG (Gallus gallus)
Further sulfation on galactose residues produces KSPG (Mus musculus)
Further sulfation on galactose residues produces KSPG (Rattus norvegicus)
Further sulfation on galactose residues produces KSPG (Sus scrofa)
Further sulfation on galactose residues produces KSPG (Xenopus tropicalis)
Authored
Jassal, B  (2011-12-01)
Reviewed
D'Eustachio, P  (2012-03-28)
Created
Jassal, B  (2012-01-11)
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