CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG

Stable Identifier
R-HSA-2046222
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Sulfation of GlcNAc residues on Keratan-PG forms KSPG
Locations in the PathwayBrowser
Summation

Carbohydrate sulfotransferases 2, 5 and 6 (CHST2, 5 and 6) catalyze the transfer of sulfate to position 6 of non-reducing ends of N-acetylglucosamine (GlcNAc) residues within keratan-like molecules (Sakaguchi et al. 2000, Lee et al. 1999, Akama et al. 2002). Keratan(4)-PG represents keratan before sulfation has occurred.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
N-acetylglucosamine 6-O-sulfotransferase activity of CHST2,5,6 [Golgi membrane]
Physical Entity
Activity
Orthologous Events