The keratan chain can be capped by N-acetylneuraminic acid

Stable Identifier
R-HSA-2046285
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The human genes ST3GAL1-4 and 6 encode for sialyltransferase1-4 and 6 respectively (Shang et al. 1999, Kim et al. 1996, Kitagawa and Paulson, 1993, Basu et al. 1993, Okajima et al. 1999). They add a sialyl residue to the growing keratan chain, blocking any further chain elongation.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL1-4,6 [Golgi membrane]
Physical Entity
Activity
Orthologous Events