Interaction of Tie2 and p85 of PI3K

Stable Identifier
R-HSA-204798
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The p85 subunit of phosphatidylinositol 3-kinase (PI3-kinase) associates with Tie2, most likely at phosphotyrosine 1102. This association leads on to the activation of Akt/PKB, a process linked to cell survival and antiapoptosis, and that may in part account for Tie2's role in vascular growth and maintenance.

Participants
Participant Of
hasEvent
Orthologous Events