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HDAC1 [nucleoplasm]
Stable Identifier
R-HSA-205021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HDA1_HUMAN, Histone deacetylase 1
Icon
Locations in the PathwayBrowser for interactor UniProt:Q96ST3 SIN3A
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G0 and Early G1 (Homo sapiens)
Recruitment of HDAC1 by p107 (RBL1) (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Recruitment of HDAC1 by p130 (RBL2) (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Homo sapiens)
RUNX1 binds SIN3A,(SIN3B) co-repressor (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of chromatin organization proteins (Homo sapiens)
SUMOylation of HDAC1 with SUMO1 (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
FOXA1 and GATA3 bind to CCND1 promoter (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
Repression of WNT target genes (Homo sapiens)
TLE recruits HDAC1 to WNT promoters (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Formation of the beta-catenin:TCF transactivating complex (Homo sapiens)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Homo sapiens)
HDAC1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13547 HDAC1
Gene Names
HDAC1, RPD3L1
Chain
chain:1-482
Reference Genes
BioGPS Gene:3065 HDAC1
COSMIC (genes):HDAC1 HDAC1
CTD Gene:3065 HDAC1
dbSNP Gene:3065 HDAC1
ENSEMBL:ENSG00000116478 HDAC1
HGNC:4852 HDAC1
KEGG Gene (Homo sapiens):3065 HDAC1
Monarch:3065 HDAC1
NCBI Gene:3065 HDAC1
OMIM:601241 HDAC1
Reference Transcript
RefSeq:NM_004964.2 HDAC1
Other Identifiers
0003710039
11747406_a_at
11755718_s_at
16662077
201209_at
2328869
2328870
2328872
2328873
2328878
2328879
2328882
2328885
2328889
2328890
2328891
2328892
2328894
2328896
2328898
2328900
2381219
2927725
3065
38771_at
476_s_at
7899774
A_14_P114672
A_23_P114656
D50405_at
GE57241
GO:0000118
GO:0000122
GO:0000228
GO:0000785
GO:0000790
GO:0000792
GO:0000976
GO:0000978
GO:0000979
GO:0001046
GO:0001085
GO:0001103
GO:0001975
GO:0002039
GO:0002376
GO:0003674
GO:0003677
GO:0003682
GO:0003714
GO:0004407
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006325
GO:0006338
GO:0006346
GO:0006357
GO:0006464
GO:0006476
GO:0006810
GO:0006950
GO:0007165
GO:0007267
GO:0007492
GO:0007596
GO:0007623
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0008285
GO:0009058
GO:0009790
GO:0009913
GO:0010629
GO:0010870
GO:0015031
GO:0016575
GO:0016580
GO:0016581
GO:0016787
GO:0016810
GO:0017053
GO:0019213
GO:0019899
GO:0021766
GO:0022607
GO:0030154
GO:0030182
GO:0031000
GO:0031492
GO:0032041
GO:0032496
GO:0032732
GO:0032760
GO:0032922
GO:0032991
GO:0033558
GO:0033613
GO:0034599
GO:0034641
GO:0035851
GO:0042475
GO:0042493
GO:0042531
GO:0042733
GO:0042826
GO:0043005
GO:0043025
GO:0043044
GO:0043066
GO:0043124
GO:0043167
GO:0043226
GO:0043524
GO:0043922
GO:0044403
GO:0044877
GO:0045652
GO:0045892
GO:0045893
GO:0045944
GO:0046676
GO:0046872
GO:0047485
GO:0048471
GO:0048511
GO:0048646
GO:0048714
GO:0048856
GO:0051059
GO:0051276
GO:0052548
GO:0055093
GO:0060766
GO:0060789
GO:0061029
GO:0061198
GO:0065003
GO:0070491
GO:0070888
GO:0070932
GO:0070933
GO:0071356
GO:0090090
GO:1900221
GO:1901796
GO:1904837
GO:1990841
GO:2000343
GO:2000676
GO:2000757
GO:2001243
ILMN_1727458
PH_hs_0004954
TC01000427.hg
U50079_s_at
g13128859_3p_at
Participant Of
hasComponent
'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm]
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm]
HDAC1 homodimer [nucleoplasm]
HDAC1:HDAC2 [nucleoplasm]
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm]
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]
NoRC:pRNA:HDAC:DNMT [nucleoplasm]
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm]
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm]
TLE1:HDAC1 [nucleoplasm]
TLE4:HDAC1 [nucleoplasm]
TLE:HDAC1 [nucleoplasm]
input
Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA
Recruitment of HDAC1 by p107 (RBL1)
Recruitment of HDAC1 by p130 (RBL2)
RUNX1 binds SIN3A,(SIN3B) co-repressor
SUMOylation of HDAC1 with SUMO1
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer
TLE recruits HDAC1 to WNT promoters
xTLE4 binds HDAC1
output
Beta-catenin displaces TLE:HDAC1 from TCF/LEF
FOXA1 and GATA3 bind to CCND1 promoter
hasMember
HDAC [nucleoplasm]
Histone deacetylase [nucleoplasm]
Other forms of this molecule
SUMO1-K444,K476-HDAC1 [nucleoplasm]
Inferred To
hdaA [nucleoplasm] (Dictyostelium discoideum)
Hdac1 [nucleoplasm] (Mus musculus)
Hdac1 [nucleoplasm] (Rattus norvegicus)
clr6 [nucleoplasm] (Schizosaccharomyces pombe)
HDAC1 [nucleoplasm] (Canis familiaris)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Gallus gallus)
HDAC1 [nucleoplasm] (Plasmodium falciparum)
HDAC1 [nucleoplasm] (Sus scrofa)
hdac1 [nucleoplasm] (Danio rerio)
hdac1 [nucleoplasm] (Xenopus tropicalis)
HOS1 [nucleoplasm] (Saccharomyces cerevisiae)
Ghost homologue of HDAC1 [nucleoplasm] (Bos taurus)
Homologues of HDAC1 [nucleoplasm] (Caenorhabditis elegans)
Homologues of HDAC1 [nucleoplasm] (Dictyostelium discoideum)
Homologues of HDAC1 [nucleoplasm] (Saccharomyces cerevisiae)
Homologues of HDAC1 [nucleoplasm] (Schizosaccharomyces pombe)
hda-1 [nucleoplasm] (Caenorhabditis elegans)
HOS2 [nucleoplasm] (Saccharomyces cerevisiae)
hda-2 [nucleoplasm] (Caenorhabditis elegans)
RPD3 [nucleoplasm] (Saccharomyces cerevisiae)
hdaB [nucleoplasm] (Dictyostelium discoideum)
phd1 [nucleoplasm] (Schizosaccharomyces pombe)
hda-3 [nucleoplasm] (Caenorhabditis elegans)
Cross References
RefSeq
NP_004955.2
ZINC - World Drugs
HDAC1_HUMAN
OpenTargets
ENSG00000116478
ZINC - FDA approved
HDAC1_HUMAN
ZINC - Substances
HDAC1_HUMAN
ZINC - Biogenic
HDAC1_HUMAN
ZINC target
Q13547
PRO
Q13547
PDB
6Z2J
,
4BKX
,
6Z2K
,
5ICN
,
1TYI
ZINC - Investigational
HDAC1_HUMAN
HPA
ENSG00000116478-HDAC1
GeneCards
Q13547
Ensembl
ENSG00000116478
,
ENST00000373548
,
ENSP00000362649
ZINC - Predictions - Purchasable
HDAC1_HUMAN
Orphanet
24588
Interactors (139)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06400 RB1
394
RB1 C706F [nucleoplasm]
(R-HSA-9659812)
RB1 R661W [nucleoplasm]
(R-HSA-9659801)
RB1 N480del [nucleoplasm]
(R-HSA-9659792)
RB1 C706Y [nucleoplasm]
(R-HSA-9659821)
RB1 R661Q [nucleoplasm]
(R-HSA-9659807)
RB1 I703_E737del [nucleoplasm]
(R-HSA-9661065)
RB1 R830_G887del [cytosol]
(R-HSA-9661059)
RB1 K791* [cytosol]
(R-HSA-9662284)
RB1 Q176* [cytosol]
(R-HSA-9661774)
RB1 S114* [cytosol]
(R-HSA-9661775)
RB1 K765* [cytosol]
(R-HSA-9662281)
RB1 W99* [cytosol]
(R-HSA-9661769)
RB1 S149* [cytosol]
(R-HSA-9661770)
RB1 E166* [cytosol]
(R-HSA-9661767)
RB1 G100* [cytosol]
(R-HSA-9661763)
RB1 E125* [cytosol]
(R-HSA-9661784)
RB1 Q121* [cytosol]
(R-HSA-9661780)
RB1 E184* [cytosol]
(R-HSA-9661781)
RB1 E137* [cytosol]
(R-HSA-9661782)
RB1 K745* [cytosol]
(R-HSA-9662288)
RB1 E209* [cytosol]
(R-HSA-9661776)
RB1 S618* [cytosol]
(R-HSA-9662240)
RB1 S463* [cytosol]
(R-HSA-9662241)
RB1 K720* [cytosol]
(R-HSA-9662269)
RB1 K429* [cytosol]
(R-HSA-9662270)
RB1 K652* [cytosol]
(R-HSA-9662271)
RB1 K715* [cytosol]
(R-HSA-9662264)
RB1 K615* [cytosol]
(R-HSA-9662266)
RB1 K412* [cytosol]
(R-HSA-9662261)
RB1 S567* [cytosol]
(R-HSA-9662218)
RB1 S807* [cytosol]
(R-HSA-9662212)
RB1 R467* [cytosol]
(R-HSA-9662213)
RB1 S834* [cytosol]
(R-HSA-9662210)
RB1 S576* [cytosol]
(R-HSA-9662237)
RB1 S758* [cytosol]
(R-HSA-9662232)
RB1 R7Pfs*24 [cytosol]
(R-HSA-9686292)
RB1 S443* [cytosol]
(R-HSA-9662230)
RB1 S648* [cytosol]
(R-HSA-9662224)
RB1 S391* [cytosol]
(R-HSA-9662225)
RB1 S829* [cytosol]
(R-HSA-9662226)
RB1 D32Tfs*33 [cytosol]
(R-HSA-9688044)
RB1 Y651Ifs*7 [cytosol]
(R-HSA-9688045)
RB1 K143Mfs*19 [cytosol]
(R-HSA-9688046)
RB1 V754Sfs*4 [cytosol]
(R-HSA-9688047)
RB1 L44Rfs*4 [cytosol]
(R-HSA-9688040)
RB1 E97Gfs*13 [cytosol]
(R-HSA-9688041)
RB1 I679* [cytosol]
(R-HSA-9688042)
RB1 W195* [cytosol]
(R-HSA-9689579)
RB1 G100Efs*11 [cytosol]
(R-HSA-9688043)
RB1 S648Tfs*4 [cytosol]
(R-HSA-9688036)
RB1 H281Qfs*6 [cytosol]
(R-HSA-9688037)
RB1 Q384* [cytosol]
(R-HSA-9661925)
RB1 S182Yfs*2 [cytosol]
(R-HSA-9688038)
RB1 L343Sfs*3 [cytosol]
(R-HSA-9688039)
RB1 L337Wfs*12 [cytosol]
(R-HSA-9688032)
RB1 S318* [cytosol]
(R-HSA-9688033)
RB1 N627Mfs*16 [cytosol]
(R-HSA-9688034)
RB1 N290Kfs*20 [cytosol]
(R-HSA-9688035)
RB1 F299Lfs*4 [cytosol]
(R-HSA-9688060)
RB1 Q637* [cytosol]
(R-HSA-9662460)
RB1 L76* [cytosol]
(R-HSA-9688061)
RB1 Q762* [cytosol]
(R-HSA-9662461)
RB1 Y655Lfs*4 [cytosol]
(R-HSA-9688062)
RB1 N480Kfs*13 [cytosol]
(R-HSA-9688063)
RB1 Q444* [cytosol]
(R-HSA-9662463)
RB1 T77Lfs*34 [cytosol]
(R-HSA-9688056)
RB1 E747Gfs*3 [cytosol]
(R-HSA-9688057)
RB1 M825* [cytosol]
(R-HSA-9688058)
RB1 L649Ffs*11 [cytosol]
(R-HSA-9688059)
RB1 N472Ifs*6 [cytosol]
(R-HSA-9688052)
RB1 Y813Kfs*12 [cytosol]
(R-HSA-9688053)
RB1 I324Mfs*17 [cytosol]
(R-HSA-9688054)
RB1 M460Ifs*3 [cytosol]
(R-HSA-9688055)
RB1 Y655Ifs*3 [cytosol]
(R-HSA-9688048)
RB1 L769Cfs*41 [cytosol]
(R-HSA-9688049)
RB1 P28Lfs*37 [cytosol]
(R-HSA-9688050)
RB1 E677Dfs*19 [cytosol]
(R-HSA-9688051)
RB1 P370Lfs*10 [cytosol]
(R-HSA-9688012)
RB1 N593Tfs*11 [cytosol]
(R-HSA-9688013)
RB1 K329* [cytosol]
(R-HSA-9661901)
RB1 S249Ffs*22 [cytosol]
(R-HSA-9688014)
RB1 K240* [cytosol]
(R-HSA-9661902)
RB1 L199Ffs*4 [cytosol]
(R-HSA-9688015)
RB1 P253Gfs*5 [cytosol]
(R-HSA-9688008)
RB1 K289* [cytosol]
(R-HSA-9661896)
RB1 S360Pfs*2 [cytosol]
(R-HSA-9688009)
RB1 E323Kfs*9 [cytosol]
(R-HSA-9688010)
RB1 L326* [cytosol]
(R-HSA-9688011)
RB1 P808Kfs*12 [cytosol]
(R-HSA-9688004)
RB1 D584Nfs*2 [cytosol]
(R-HSA-9688005)
RB1 N406Kfs*4 [cytosol]
(R-HSA-9688006)
RB1 K417Wfs*23 [cytosol]
(R-HSA-9688007)
RB1 L797Ffs*18 [cytosol]
(R-HSA-9688000)
RB1 Q266Hfs*2 [cytosol]
(R-HSA-9688001)
RB1 R255* [cytosol]
(R-HSA-9661889)
RB1 K4* [cytosol]
(R-HSA-9661377)
RB1 P641Afs*12 [cytosol]
(R-HSA-9688002)
RB1 V450Sfs*13 [cytosol]
(R-HSA-9688003)
RB1 K524Rfs*28 [cytosol]
(R-HSA-9688028)
RB1 E280* [cytosol]
(R-HSA-9661916)
RB1 M825Ifs*13 [cytosol]
(R-HSA-9688029)
RB1 M761Nfs*21 [cytosol]
(R-HSA-9688030)
RB1 A11Rfs*20 [cytosol]
(R-HSA-9688031)
RB1 E275* [cytosol]
(R-HSA-9661919)
RB1 A635Gfs*6 [cytosol]
(R-HSA-9688024)
RB1 Q266* [cytosol]
(R-HSA-9661912)
RB1 I66Yfs*11 [cytosol]
(R-HSA-9688025)
RB1 Q257* [cytosol]
(R-HSA-9661913)
RB1 P39Rfs*26 [cytosol]
(R-HSA-9688026)
RB1 T664Nfs*4 [cytosol]
(R-HSA-9688027)
RB1 Y771Lfs*24 [cytosol]
(R-HSA-9688020)
RB1 R320Dfs*12 [cytosol]
(R-HSA-9688021)
RB1 E282* [cytosol]
(R-HSA-9661909)
RB1 L277Pfs*9 [cytosol]
(R-HSA-9688022)
RB1 I124* [cytosol]
(R-HSA-9688023)
RB1 N803Tfs*7 [cytosol]
(R-HSA-9688016)
RB1 M386Ifs*11 [cytosol]
(R-HSA-9688017)
RB1 E72Vfs*34 [cytosol]
(R-HSA-9688018)
RB1 R150Kfs*7 [cytosol]
(R-HSA-9688019)
RB1 L743* [cytosol]
(R-HSA-9687980)
RB1 R7Efs*58 [cytosol]
(R-HSA-9687981)
RB1 T140Nfs*6 [cytosol]
(R-HSA-9687982)
RB1 D479Efs*16 [cytosol]
(R-HSA-9687983)
RB1 L199* [cytosol]
(R-HSA-9661871)
RB1 G801* [cytosol]
(R-HSA-9662377)
RB1 S215* [cytosol]
(R-HSA-9661866)
RB1 G435* [cytosol]
(R-HSA-9662368)
RB1 G581* [cytosol]
(R-HSA-9662369)
RB1 L134* [cytosol]
(R-HSA-9687996)
RB1 Y529Lfs*26 [cytosol]
(R-HSA-9687997)
RB1 S816Qfs*10 [cytosol]
(R-HSA-9687998)
RB1 E693Nfs*3 [cytosol]
(R-HSA-9687999)
RB1 D346Rfs*4 [cytosol]
(R-HSA-9687992)
RB1 Q35* [cytosol]
(R-HSA-9661368)
RB1 I806Lfs*10 [cytosol]
(R-HSA-9687993)
RB1 E54* [cytosol]
(R-HSA-9661369)
RB1 L199Yfs*2 [cytosol]
(R-HSA-9687994)
RB1 E48* [cytosol]
(R-HSA-9661370)
RB1 N854* [cytosol]
(R-HSA-9687995)
RB1 W75* [cytosol]
(R-HSA-9661371)
RB1 L389Ffs*3 [cytosol]
(R-HSA-9687988)
RB1 S230* [cytosol]
(R-HSA-9661876)
RB1 H483Sfs*10 [cytosol]
(R-HSA-9687989)
RB1 S842* [cytosol]
(R-HSA-9687990)
RB1 W78* [cytosol]
(R-HSA-9661366)
RB1 G449Efs*8 [cytosol]
(R-HSA-9687991)
RB1 K63* [cytosol]
(R-HSA-9661367)
RB1 K537Nfs*14 [cytosol]
(R-HSA-9687984)
RB1 L206* [cytosol]
(R-HSA-9661872)
RB1 K63Rfs*38 [cytosol]
(R-HSA-9687985)
RB1 P732Lfs*12 [cytosol]
(R-HSA-9687986)
RB1 L158* [cytosol]
(R-HSA-9661874)
RB1 A562Hfs*49 [cytosol]
(R-HSA-9687987)
RB1 E72* [cytosol]
(R-HSA-9661363)
RB1 G540Afs*3 [cytosol]
(R-HSA-9688172)
RB1 N328Ifs*4 [cytosol]
(R-HSA-9688173)
RB1 E843* [cytosol]
(R-HSA-9662573)
RB1 L385* [cytosol]
(R-HSA-9688174)
RB1 E464* [cytosol]
(R-HSA-9662574)
RB1 N123Tfs*2 [cytosol]
(R-HSA-9688175)
RB1 E112Dfs*6 [cytosol]
(R-HSA-9688168)
RB1 E748* [cytosol]
(R-HSA-9662568)
RB1 M148Ifs*8 [cytosol]
(R-HSA-9688169)
RB1 R661* [cytosol]
(R-HSA-9688170)
RB1 Y453* [cytosol]
(R-HSA-9688164)
RB1 K95* [cytosol]
(R-HSA-9661540)
RB1 M484Vfs*8 [cytosol]
(R-HSA-9688165)
RB1 E533* [cytosol]
(R-HSA-9662565)
RB1 G86* [cytosol]
(R-HSA-9661541)
RB1 V654Sfs*14 [cytosol]
(R-HSA-9688166)
RB1 E747* [cytosol]
(R-HSA-9662566)
RB1 E79* [cytosol]
(R-HSA-9661542)
RB1 C553Wfs*53 [cytosol]
(R-HSA-9688167)
RB1 E677* [cytosol]
(R-HSA-9662567)
RB1 K96* [cytosol]
(R-HSA-9661543)
RB1 C102Yfs*7 [cytosol]
(R-HSA-9688160)
RB1 E737* [cytosol]
(R-HSA-9662560)
RB1 E97* [cytosol]
(R-HSA-9661536)
RB1 R579Qfs*29 [cytosol]
(R-HSA-9688161)
RB1 A525Pfs*7 [cytosol]
(R-HSA-9688162)
RB1 L542Kfs*11 [cytosol]
(R-HSA-9688163)
RB1 F482Sfs*10 [cytosol]
(R-HSA-9688188)
RB1 L797* [cytosol]
(R-HSA-9688189)
RB1 P250Afs*16 [cytosol]
(R-HSA-9688190)
RB1 S194Ffs*7 [cytosol]
(R-HSA-9688191)
RB1 N623Qfs*15 [cytosol]
(R-HSA-9688184)
RB1 T9Rfs*56 [cytosol]
(R-HSA-9688185)
RB1 Y813Qfs*10 [cytosol]
(R-HSA-9688187)
RB1 I768Cfs*23 [cytosol]
(R-HSA-9688180)
RB1 L477Mfs*17 [cytosol]
(R-HSA-9688181)
RB1 E675* [cytosol]
(R-HSA-9662581)
RB1 V654Cfs*4 [cytosol]
(R-HSA-9688182)
RB1 F650Lfs*5 [cytosol]
(R-HSA-9688183)
RB1 P39Sfs*10 [cytosol]
(R-HSA-9688176)
RB1 H281Sfs*2 [cytosol]
(R-HSA-9688177)
RB1 E551* [cytosol]
(R-HSA-9662577)
RB1 C61Vfs*4 [cytosol]
(R-HSA-9688178)
RB1 D145Ifs*8 [cytosol]
(R-HSA-9688179)
RB1 M148Hfs*9 [cytosol]
(R-HSA-9688140)
RB1 E837* [cytosol]
(R-HSA-9662540)
RB1 L158Mfs*19 [cytosol]
(R-HSA-9688141)
RB1 L832Ffs*5 [cytosol]
(R-HSA-9688142)
RB1 E440* [cytosol]
(R-HSA-9662542)
RB1 D224Afs*40 [cytosol]
(R-HSA-9688136)
RB1 P822Qfs*4 [cytosol]
(R-HSA-9688137)
RB1 M148Vfs*8 [cytosol]
(R-HSA-9688138)
RB1 L670Cfs*7 [cytosol]
(R-HSA-9688139)
RB1 E465* [cytosol]
(R-HSA-9662532)
RB1 S414Kfs*14 [cytosol]
(R-HSA-9688133)
RB1 K548Nfs*3 [cytosol]
(R-HSA-9688134)
RB1 L135Tfs*5 [cytosol]
(R-HSA-9688135)
RB1 Q207Tfs*5 [cytosol]
(R-HSA-9688128)
RB1 Q384Tfs*11 [cytosol]
(R-HSA-9688129)
RB1 L797Ffs*14 [cytosol]
(R-HSA-9688130)
RB1 P232Rfs*4 [cytosol]
(R-HSA-9688131)
RB1 T497Hfs*22 [cytosol]
(R-HSA-9688156)
RB1 E817* [cytosol]
(R-HSA-9662556)
RB1 N367* [cytosol]
(R-HSA-9688157)
RB1 L809Rfs*17 [cytosol]
(R-HSA-9688158)
RB1 E693* [cytosol]
(R-HSA-9662558)
RB1 K80* [cytosol]
(R-HSA-9661534)
RB1 W99Lfs*11 [cytosol]
(R-HSA-9688159)
RB1 A15Pfs*3 [cytosol]
(R-HSA-9688152)
RB1 Y239Lfs*25 [cytosol]
(R-HSA-9688153)
RB1 D571Lfs*41 [cytosol]
(R-HSA-9688154)
RB1 N186Ifs*6 [cytosol]
(R-HSA-9688155)
RB1 E837Dfs*12 [cytosol]
(R-HSA-9688148)
RB1 E672* [cytosol]
(R-HSA-9662548)
RB1 H483Yfs*9 [cytosol]
(R-HSA-9688149)
RB1 R775Gfs*35 [cytosol]
(R-HSA-9688150)
RB1 E580* [cytosol]
(R-HSA-9662550)
RB1 G617Rfs*36 [cytosol]
(R-HSA-9688151)
RB1 E492* [cytosol]
(R-HSA-9662551)
RB1 A333Ffs*13 [cytosol]
(R-HSA-9688144)
RB1 L564Sfs*47 [cytosol]
(R-HSA-9688145)
RB1 D156Vfs*19 [cytosol]
(R-HSA-9688147)
RB1 C438Vfs*19 [cytosol]
(R-HSA-9688108)
RB1 C278* [cytosol]
(R-HSA-9688109)
RB1 E209Vfs*3 [cytosol]
(R-HSA-9688110)
RB1 T116Lfs*8 [cytosol]
(R-HSA-9688111)
RB1 R698Afs*22 [cytosol]
(R-HSA-9688104)
RB1 V419* [cytosol]
(R-HSA-9688105)
RB1 I415Nfs*13 [cytosol]
(R-HSA-9688106)
RB1 Y173Ffs*11 [cytosol]
(R-HSA-9688107)
RB1 N133Tfs*3 [cytosol]
(R-HSA-9688100)
RB1 M695Rfs*10 [cytosol]
(R-HSA-9688101)
RB1 R418Sfs*9 [cytosol]
(R-HSA-9688102)
RB1 Q689* [cytosol]
(R-HSA-9662502)
RB1 A74Efs*4 [cytosol]
(R-HSA-9688103)
RB1 W99Yfs*5 [cytosol]
(R-HSA-9688096)
RB1 G442Dfs*15 [cytosol]
(R-HSA-9688097)
RB1 N258Efs*11 [cytosol]
(R-HSA-9688098)
RB1 S182Ifs*3 [cytosol]
(R-HSA-9688099)
RB1 Q436* [cytosol]
(R-HSA-9662499)
RB1 Q395Pfs*11 [cytosol]
(R-HSA-9688124)
RB1 Y606Lfs*47 [cytosol]
(R-HSA-9688125)
RB1 E539* [cytosol]
(R-HSA-9662525)
RB1 L317* [cytosol]
(R-HSA-9688126)
RB1 F104Lfs*7 [cytosol]
(R-HSA-9688127)
RB1 E691* [cytosol]
(R-HSA-9662527)
RB1 D340Yfs*5 [cytosol]
(R-HSA-9688120)
RB1 K740Tfs*10 [cytosol]
(R-HSA-9688121)
RB1 H483Ifs*12 [cytosol]
(R-HSA-9688122)
RB1 R611Lfs*43 [cytosol]
(R-HSA-9688123)
RB1 V291Ifs*9 [cytosol]
(R-HSA-9688116)
RB1 N133* [cytosol]
(R-HSA-9688117)
RB1 R334* [cytosol]
(R-HSA-9688118)
RB1 D697Qfs*23 [cytosol]
(R-HSA-9688119)
RB1 L647Ffs*5 [cytosol]
(R-HSA-9688112)
RB1 I723Nfs*28 [cytosol]
(R-HSA-9688113)
RB1 L486Ifs*6 [cytosol]
(R-HSA-9688114)
RB1 S565* [cytosol]
(R-HSA-9688115)
RB1 Y529Tfs*3 [cytosol]
(R-HSA-9688076)
RB1 Q631* [cytosol]
(R-HSA-9662476)
RB1 S318Nfs*13 [cytosol]
(R-HSA-9688077)
RB1 D856Efs*17 [cytosol]
(R-HSA-9688078)
RB1 P595Lfs*16 [cytosol]
(R-HSA-9688079)
RB1 P777Lfs*33 [cytosol]
(R-HSA-9688072)
RB1 G310Dfs*22 [cytosol]
(R-HSA-9688073)
RB1 P250Sfs*20 [cytosol]
(R-HSA-9688074)
RB1 Q850* [cytosol]
(R-HSA-9662474)
RB1 I124Rfs*6 [cytosol]
(R-HSA-9688075)
RB1 Q702* [cytosol]
(R-HSA-9662475)
RB1 E748Dfs*6 [cytosol]
(R-HSA-9688068)
RB1 Q736* [cytosol]
(R-HSA-9662468)
RB1 R798Qfs*4 [cytosol]
(R-HSA-9688069)
RB1 S588Ffs*6 [cytosol]
(R-HSA-9688070)
RB1 K574* [cytosol]
(R-HSA-9688071)
RB1 D156Mfs*19 [cytosol]
(R-HSA-9688064)
RB1 Y771Cfs*23 [cytosol]
(R-HSA-9688065)
RB1 I66Dfs*44 [cytosol]
(R-HSA-9688066)
RB1 Q685* [cytosol]
(R-HSA-9662466)
RB1 E125Kfs*11 [cytosol]
(R-HSA-9688067)
RB1 Y655Lfs*13 [cytosol]
(R-HSA-9688092)
RB1 R828Kfs*10 [cytosol]
(R-HSA-9688093)
RB1 Y659Ifs*4 [cytosol]
(R-HSA-9688094)
RB1 Q846* [cytosol]
(R-HSA-9662494)
RB1 E97Nfs*14 [cytosol]
(R-HSA-9688095)
RB1 Q770* [cytosol]
(R-HSA-9662495)
RB1 C666* [cytosol]
(R-HSA-9688088)
RB1 Q471* [cytosol]
(R-HSA-9662488)
RB1 R71Efs*39 [cytosol]
(R-HSA-9688089)
RB1 Q504* [cytosol]
(R-HSA-9662489)
RB1 R798Tfs*17 [cytosol]
(R-HSA-9688090)
RB1 Q639* [cytosol]
(R-HSA-9662490)
RB1 N328* [cytosol]
(R-HSA-9688091)
RB1 S576Rfs*34 [cytosol]
(R-HSA-9688084)
RB1 T726Nfs*25 [cytosol]
(R-HSA-9688085)
RB1 Q597* [cytosol]
(R-HSA-9662485)
RB1 I532Nfs*57 [cytosol]
(R-HSA-9688086)
RB1 K577Rfs*34 [cytosol]
(R-HSA-9688087)
RB1 R73Sfs*36 [cytosol]
(R-HSA-9688080)
RB1 E413Kfs*4 [cytosol]
(R-HSA-9688081)
RB1 K844Sfs*5 [cytosol]
(R-HSA-9688082)
RB1 A17Pfs*3 [cytosol]
(R-HSA-9688083)
RB1 Q395* [cytosol]
(R-HSA-9660655)
RB1 L523* [cytosol]
(R-HSA-9662176)
RB1 R251* [cytosol]
(R-HSA-9660640)
RB1 L389* [cytosol]
(R-HSA-9662178)
RB1 Q217* [cytosol]
(R-HSA-9660668)
RB1 Q344* [cytosol]
(R-HSA-9660669)
RB1 S634* [cytosol]
(R-HSA-9662207)
RB1 S565* [cytosol]
(R-HSA-9662200)
RB1 S397* [cytosol]
(R-HSA-9662202)
RB1 S838* [cytosol]
(R-HSA-9662203)
RB1 R556* [cytosol]
(R-HSA-9660661)
RB1 R787* [cytosol]
(R-HSA-9660656)
RB1 G304* [cytosol]
(R-HSA-9662152)
RB1 W516* [cytosol]
(R-HSA-9662660)
RB1 W681* [cytosol]
(R-HSA-9662661)
RB1 E322* [cytosol]
(R-HSA-9662149)
RB1 W563* [cytosol]
(R-HSA-9662656)
RB1 L550* [cytosol]
(R-HSA-9662173)
RB1 R552* [cytosol]
(R-HSA-9660637)
RB1 L512* [cytosol]
(R-HSA-9662168)
RB1 R455* [cytosol]
(R-HSA-9660632)
RB1 R763* [cytosol]
(R-HSA-9662681)
RB1 L779* [cytosol]
(R-HSA-9662169)
RB1 R445* [cytosol]
(R-HSA-9660633)
RB1 R544* [cytosol]
(R-HSA-9662677)
RB1 R320* [cytosol]
(R-HSA-9660630)
RB1 L832* [cytosol]
(R-HSA-9662167)
RB1 Y498* [cytosol]
(R-HSA-9662634)
RB1 Y446* [cytosol]
(R-HSA-9662628)
RB1 Y655* [cytosol]
(R-HSA-9662629)
RB1 E323* [cytosol]
(R-HSA-9662142)
RB1 E364* [cytosol]
(R-HSA-9662143)
RB1 C489* [cytosol]
(R-HSA-9662649)
RB1 G310* [cytosol]
(R-HSA-9662137)
RB1 L335* [cytosol]
(R-HSA-9662139)
RB1 E313* [cytosol]
(R-HSA-9662133)
RB1 E315* [cytosol]
(R-HSA-9662131)
RB1 D479Vfs*14 [cytosol]
(R-HSA-9688204)
RB1 C489Lfs*5 [cytosol]
(R-HSA-9688205)
RB1 Y454* [cytosol]
(R-HSA-9662605)
RB1 E137Rfs*3 [cytosol]
(R-HSA-9688206)
RB1 L676Ffs*16 [cytosol]
(R-HSA-9688207)
RB1 Y728* [cytosol]
(R-HSA-9662607)
RB1 I799Ffs*11 [cytosol]
(R-HSA-9688200)
RB1 D346Vfs*17 [cytosol]
(R-HSA-9688201)
RB1 F514Pfs*8 [cytosol]
(R-HSA-9688202)
RB1 N593Sfs*5 [cytosol]
(R-HSA-9688203)
RB1 T58Yfs*52 [cytosol]
(R-HSA-9688196)
RB1 N522Ifs*2 [cytosol]
(R-HSA-9688197)
RB1 C553Vfs*58 [cytosol]
(R-HSA-9688198)
RB1 P609Cfs*43 [cytosol]
(R-HSA-9688199)
RB1 N269* [cytosol]
(R-HSA-9688192)
RB1 E287Rfs*2 [cytosol]
(R-HSA-9688193)
RB1 E492Lfs*4 [cytosol]
(R-HSA-9688194)
RB1 Q383Nfs*3 [cytosol]
(R-HSA-9688195)
RB1 Y606* [cytosol]
(R-HSA-9662617)
RB1 Y756* [cytosol]
(R-HSA-9662619)
RB1 Y790* [cytosol]
(R-HSA-9662612)
RB1 T502Nfs*17 [cytosol]
(R-HSA-9688208)
RB1 Y709* [cytosol]
(R-HSA-9662608)
RB1 Y749* [cytosol]
(R-HSA-9662611)
RB1 T738_R775del [nucleoplasm]
(R-HSA-9661042)
RB1 [cytosol]
(R-HSA-9660621)
hyperphosphorylated RB1 [nucleoplasm]
(R-HSA-188389)
p-S249-RB1 [nucleoplasm]
(R-HSA-9687343)
p-S230-RB1 [nucleoplasm]
(R-HSA-9687336)
p-T356-RB1 [nucleoplasm]
(R-HSA-9687339)
p-T826-RB1 [nucleoplasm]
(R-HSA-9687334)
p-S252-RB1 [nucleoplasm]
(R-HSA-9687335)
p-S807-RB1 [nucleoplasm]
(R-HSA-9687356)
p-T821-RB1 [nucleoplasm]
(R-HSA-9687357)
p-S795-RB1 [nucleoplasm]
(R-HSA-69226)
p-S612-RB1 [nucleoplasm]
(R-HSA-9687352)
p-S780-RB1 [nucleoplasm]
(R-HSA-9687353)
p-S811-RB1 [nucleoplasm]
(R-HSA-9687354)
RB1 [nucleoplasm]
(R-HSA-68642)
p-S788-RB1 [nucleoplasm]
(R-HSA-9687347)
p-S608-RB1 [nucleoplasm]
(R-HSA-9687351)
p-T373-RB1 [nucleoplasm]
(R-HSA-9687355)
0.956
18
UniProt:O94776 MTA2
1
MTA2 [nucleoplasm]
(R-HSA-4657009)
0.944
15
UniProt:Q92769 HDAC2
2
HDAC2 [nucleoplasm]
(R-HSA-205135)
SUMO1-K462-HDAC2 [nucleoplasm]
(R-HSA-4615958)
0.94
16
UniProt:Q9UKL0 RCOR1
1
RCOR1 [nucleoplasm]
(R-HSA-996766)
0.935
11
UniProt:Q13330 MTA1
2
SUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
MTA1 [nucleoplasm]
(R-HSA-3465550)
0.914
12
UniProt:Q96ST3 SIN3A
2
SIN3A [nucleoplasm]
(R-HSA-351657)
SUMO1-SIN3A [nucleoplasm]
(R-HSA-4086071)
0.899
9
UniProt:Q09028 RBBP4
1
RBBP4 [nucleoplasm]
(R-HSA-212223)
0.895
8
UniProt:Q16576 RBBP7
1
RBBP7 [nucleoplasm]
(R-HSA-212227)
0.886
7
UniProt:Q14839 CHD4
1
CHD4 [nucleoplasm]
(R-HSA-3702078)
0.885
11
UniProt:Q8N108 MIER1
0.862
8
UniProt:Q9UBB5 MBD2
1
MBD2 [nucleoplasm]
(R-HSA-427367)
0.839
6
UniProt:O95983 MBD3
1
MBD3 [nucleoplasm]
(R-HSA-4657010)
0.823
6
UniProt:Q8WXI9 GATAD2B
1
GATAD2B [nucleoplasm]
(R-HSA-3702079)
0.788
5
UniProt:Q9HCU9 BRMS1
1
BRMS1 [nucleoplasm]
(R-HSA-4650034)
0.784
5
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.758
8
UniProt:Q96KQ7 EHMT2
1
EHMT2 [nucleoplasm]
(R-HSA-212151)
0.737
7
UniProt:P04637 TP53
27
TP53 [cytosol]
(R-HSA-8869337)
Unfolded TP53 [cytosol]
(R-HSA-6813797)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
SUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
Me2K-370,382-TP53 [nucleoplasm]
(R-HSA-3222242)
p-S15,S33,S46-TP53 [nucleoplasm]
(R-HSA-6805268)
p-S15,S392-TP53 [nucleoplasm]
(R-HSA-3222015)
p-T55-TP53 [nucleoplasm]
(R-HSA-6805400)
p-S15,S20,S392-TP53 [nucleoplasm]
(R-HSA-6805053)
p-S15,S20,S269,T284-TP53 [nucleoplasm]
(R-HSA-6805133)
p-S315-TP53 [nucleoplasm]
(R-HSA-6805106)
Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805656)
Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805631)
Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-5628868)
Me2-K373-TP53 [nucleoplasm]
(R-HSA-6805759)
MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222226)
p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-HSA-6804378)
Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222124)
Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805719)
p-S15,S20,S46-TP53 [nucleoplasm]
(R-HSA-6798369)
p-S37-TP53 [nucleoplasm]
(R-HSA-3239022)
PolyUb,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6804446)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6793679)
PolyUb-TP53 [cytosol]
(R-HSA-6793681)
p-S15,S20-TP53 [nucleoplasm]
(R-HSA-69683)
p-S15-TP53 [nucleoplasm]
(R-HSA-69507)
TP53 [nucleoplasm]
(R-HSA-69488)
0.734
7
UniProt:Q14865 ARID5B
1
ARID5B [nucleoplasm]
(R-HSA-5423050)
0.728
6
UniProt:Q9NP50 SHCAF
0.728
6
UniProt:Q86YP4 GATAD2A
1
GATAD2A [nucleoplasm]
(R-HSA-3702077)
0.725
4
UniProt:Q5PSV4 BRM1L
0.725
4
UniProt:Q6PJG2 MDEAS
0.725
5
UniProt:O75446 SAP30
1
SAP30 [nucleoplasm]
(R-HSA-351693)
0.725
5
UniProt:Q9H7L9 SUDS3
2
SUDS3 [nucleoplasm]
(R-HSA-351696)
K63polyUb-SUDS3 [nucleoplasm]
(R-HSA-6782790)
0.725
4
UniProt:P78371 CCT2
3
CCT2 [extracellular region]
(R-HSA-6806220)
CCT2 [azurophil granule lumen]
(R-HSA-6799356)
CCT2 [cytosol]
(R-HSA-390464)
0.725
5
UniProt:Q9NP66 HM20A
0.725
5
UniProt:O14519 CDKA1
0.725
5
UniProt:Q9BTC8 MTA3
1
MTA3 [nucleoplasm]
(R-HSA-4657013)
0.725
5
UniProt:Q9H147 TDIF1
0.725
5
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.69
4
UniProt:P62805 H4C1
19
SUMO3-HIST1H4 [nucleoplasm]
(R-HSA-4570531)
HIST1H4A [extracellular region]
(R-HSA-977569)
SUMO1-HIST1H4 [nucleoplasm]
(R-HSA-4570518)
4xAcK-HIST1H4A [nucleoplasm]
(R-HSA-427390)
AcK5,12-HIST1H4A [nucleoplasm]
(R-HSA-212078)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-427469)
AcK13-HIST1H4 [nucleoplasm]
(R-HSA-4568744)
AcK6-HIST1H4 [nucleoplasm]
(R-HSA-4568748)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-4568749)
AcK9-HIST1H4 [nucleoplasm]
(R-HSA-4568758)
Me2aR4-HIST1H4 [nucleoplasm]
(R-HSA-5229015)
Me2sR4-HIST1H4 [nucleoplasm]
(R-HSA-4754243)
MeR4-HIST1H4 [nucleoplasm]
(R-HSA-4754240)
Me3K21-HIST1H4 [nucleoplasm]
(R-HSA-5651656)
MeK21-HIST1H4 [nucleoplasm]
(R-HSA-5423110)
AcK-HIST1H4 [nucleoplasm]
(R-HSA-3451124)
MeK-HIST1H4A [nucleoplasm]
(R-HSA-2172676)
HIST1H4 [nucleoplasm]
(R-HSA-181902)
Me2K21-HIST1H4 [nucleoplasm]
(R-HSA-5651652)
0.688
3
UniProt:Q12873 CHD3
2
SUMO1-K1971-CHD3 [nucleoplasm]
(R-HSA-8956372)
CHD3 [nucleoplasm]
(R-HSA-4657012)
0.677
6
UniProt:P19838 NFKB1
8
NFKB1(1-968) [extracellular region]
(R-HSA-6806304)
NFKB1(1-968) [specific granule lumen]
(R-HSA-6799557)
NFKB1(1-968) [secretory granule lumen]
(R-HSA-6801004)
NFKB1(1-433) [nucleoplasm]
(R-HSA-177655)
NFKB1(1-433) [cytosol]
(R-HSA-168168)
NFKB1(1-968) [cytosol]
(R-HSA-451607)
p-S927,S932-NFKB1(1-968) [cytosol]
(R-HSA-451611)
3xUb-p-S927,S932-NFKB1(1-968) [cytosol]
(R-HSA-451619)
0.667
5
UniProt:Q04206 RELA
6
MeK310-RELA [nucleoplasm]
(R-HSA-8865233)
SUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-HSA-4755466)
p-S276,5xAcK-RELA [nucleoplasm]
(R-HSA-5660642)
p-S276-RELA [nucleoplasm]
(R-HSA-5624468)
RELA [nucleoplasm]
(R-HSA-177676)
RELA [cytosol]
(R-HSA-168172)
0.656
6
UniProt:Q96N64 PWP2A
0.649
5
UniProt:Q99832 CCT7
1
CCT7 [cytosol]
(R-HSA-390451)
0.643
4
UniProt:O75182 SIN3B
1
SIN3B [nucleoplasm]
(R-HSA-3006450)
0.643
3
UniProt:P48643 CCT5
1
CCT5 [cytosol]
(R-HSA-390447)
0.643
4
UniProt:O15417 TNC18
0.643
3
UniProt:Q96QT6 PHF12
0.643
4
UniProt:Q9P2R6 RERE
0.643
3
UniProt:Q14687 GSE1
0.643
3
UniProt:Q9P0W2 HMG20B
1
HMG20B [nucleoplasm]
(R-HSA-996745)
0.643
3
UniProt:Q99471 PFDN5
1
PFDN5 [cytosol]
(R-HSA-379548)
0.643
4
UniProt:P49368 CCT3
1
CCT3 [cytosol]
(R-HSA-390463)
0.643
4
UniProt:P50991 CCT4
1
CCT4 [cytosol]
(R-HSA-390458)
0.643
4
UniProt:Q7Z589 EMSY
0.643
3
UniProt:Q8WUU5 GATD1
0.643
3
UniProt:Q9UBW7 ZMYM2
6
ZMYM2(1-1059)-FLT3(594-993) fusion [cytosol]
(R-HSA-9703310)
ZMYM2(1-1057)-FLT3(586-993) fusion [cytosol]
(R-HSA-9703311)
ZMYM2(1-1057)-p-5Y FLT3(586-993) fusion [cytosol]
(R-HSA-9703319)
ZMYM2(1-1059)-p-4Y FLT3(594-993) fusion [cytosol]
(R-HSA-9703309)
ZMYM2-FGFR1 fusion [cytosol]
(R-HSA-1604544)
ZMYM2-p-2Y-FGFR1 fusion [cytosol]
(R-HSA-1839016)
0.643
3
UniProt:Q96PN7 TREF1
0.643
3
UniProt:P61758 VBP1
1
VBP1 [cytosol]
(R-HSA-379543)
0.643
3
UniProt:Q8N680 ZBTB2
0.643
3
UniProt:P61964 WDR5
1
WDR5 [nucleoplasm]
(R-HSA-1629838)
0.643
3
UniProt:O75362 ZNF217
1
ZNF217 [nucleoplasm]
(R-HSA-9011738)
0.643
3
UniProt:P17987 TCP1
1
TCP1 [cytosol]
(R-HSA-390448)
0.643
4
UniProt:O95863 SNAI1
1
SNAI1 [nucleoplasm]
(R-HSA-2980903)
0.642
3
UniProt:Q6PH81 CP087
0.623
4
UniProt:Q9C0K0 BC11B
0.602
3
UniProt:P03372 ESR1
8
SUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.597
4
UniProt:P26358 DNMT1
2
DNMT1 [nucleoplasm]
(R-HSA-212181)
SUMO1-K-DNMT1 [nucleoplasm]
(R-HSA-4655353)
0.597
7
UniProt:P68400 CSNK2A1
2
CSNK2A1 [cytosol]
(R-HSA-201713)
CSNK2A1 [nucleoplasm]
(R-HSA-6805057)
0.59
2
UniProt:Q05516 ZBTB16
1
ZBTB16 [cytosol]
(R-HSA-976047)
0.589
2
UniProt:Q9Y618 NCOR2
2
NCOR2 [nucleoplasm]
(R-HSA-442469)
SUMO1-K672-NCOR2 [nucleoplasm]
(R-HSA-3927904)
0.589
2
UniProt:Q01094 E2F1
2
p-E2F1 [nucleoplasm]
(R-HSA-187911)
E2F1 [nucleoplasm]
(R-HSA-68639)
0.589
2
UniProt:Q9NQX1 PRDM5
0.576
3
UniProt:P17844 DDX5
4
DDX5 [cytosol]
(R-HSA-9682643)
DDX5 [nucleoplasm]
(R-HSA-3900136)
SUMO2-K53-DDX5 [nucleoplasm]
(R-HSA-3900186)
SUMO1-K53-DDX5 [nucleoplasm]
(R-HSA-3900041)
0.576
4
UniProt:O60341-1 KDM1A
0.564
2
UniProt:O95365 ZBT7A
0.564
2
UniProt:P08047 SP1
1
SP1 [nucleoplasm]
(R-HSA-1592223)
0.564
2
UniProt:Q9UKG1 APPL1
1
APPL1 [endosome membrane]
(R-HSA-373630)
0.564
2
UniProt:P17542 TAL1
1
TAL1 [nucleoplasm]
(R-HSA-8956511)
0.558
5
UniProt:Q9UJW3 DNMT3L
1
DNMT3L [nucleoplasm]
(R-HSA-5334123)
0.544
3
UniProt:Q99497 PARK7
7
PARK7 [nucleoplasm]
(R-HSA-3900141)
SUMO1-K130-PARK7 [nucleoplasm]
(R-HSA-4085351)
PolyUb-Misfolded PARK7 [late endosome lumen]
(R-HSA-9660005)
Misfolded PARK7 [cytosol]
(R-HSA-9641100)
Ub-Misfolded PARK7 [cytosol]
(R-HSA-9641123)
PolyUb-Misfolded PARK7 [cytosol]
(R-HSA-9641128)
PolyUb-Misfolded PARK7 [lysosomal lumen]
(R-HSA-9659997)
0.537
4
UniProt:P22670 RFX1
0.534
2
UniProt:Q8N5A5 ZGPAT
0.532
3
UniProt:O60315 ZEB2
0.532
9
UniProt:Q17R98 ZN827
0.527
2
UniProt:Q9P2K3-3 RCOR3
0.527
2
UniProt:Q92766 RREB1
0.527
2
UniProt:P85037 FOXK1
1
FOXK1 [nucleoplasm]
(R-HSA-5689673)
0.527
2
UniProt:Q9HAJ7 SAP30L
1
SAP30L [nucleoplasm]
(R-HSA-351698)
0.527
2
UniProt:Q8IZ40 RCOR2
0.527
2
UniProt:O15014 ZN609
0.527
2
UniProt:Q14839-2 CHD4
0.527
2
UniProt:Q9H9B1 EHMT1
1
EHMT1 [nucleoplasm]
(R-HSA-1183226)
0.527
2
IntAct:EBI-1566859 IL2
0.527
3
UniProt:Q4LE39-2 ARID4B
0.527
2
UniProt:Q9H0E3 SAP130
1
SAP130 [nucleoplasm]
(R-HSA-3006732)
0.527
2
UniProt:Q14202 ZMYM3
0.527
2
UniProt:Q9R190 Mta2
1
Mta2 [nucleoplasm]
(R-MMU-5096453)
0.527
2
UniProt:Q9UHV9 PFDN2
1
PFDN2 [cytosol]
(R-HSA-379544)
0.527
2
UniProt:P40227 CCT6A
1
CCT6A [cytosol]
(R-HSA-390454)
0.527
3
UniProt:O60925 PFDN1
1
PFDN1 [cytosol]
(R-HSA-379541)
0.527
2
UniProt:Q9P2K3 RCOR3
0.527
2
UniProt:P29375-2 KDM5A
0.527
2
UniProt:Q9Y232-2 CDYL
0.527
2
UniProt:Q96BD5-2 PHF21A
0.527
2
UniProt:Q9H2P0 ADNP
0.527
2
UniProt:Q8IWI9 MGA
1
MGA [nucleoplasm]
(R-HSA-8953093)
0.527
2
UniProt:P50990 CCT8
5
CCT8 [extracellular region]
(R-HSA-6806238)
CCT8 [secretory granule lumen]
(R-HSA-6801035)
CCT8 [ficolin-1-rich granule lumen]
(R-HSA-6800894)
CCT8 [azurophil granule lumen]
(R-HSA-6799369)
CCT8 [cytosol]
(R-HSA-390449)
0.527
3
UniProt:O75182-2 SIN3B
0.527
2
UniProt:Q09028-2 RBBP4
0.527
2
UniProt:Q92610 ZN592
0.527
2
UniProt:Q8N344 MIER2
0.527
2
UniProt:P0C0S8 H2AC11
11
Ub-HIST1H2AG [nucleoplasm]
(R-HSA-6782508)
K63polyUb-HIST1H2AG [nucleoplasm]
(R-HSA-6783237)
Ack6-HIST1H2AG [nucleoplasm]
(R-HSA-4568595)
Ack-HIST1H2AG [nucleoplasm]
(R-HSA-4551311)
Me2aR30-HIST1H2AG [nucleoplasm]
(R-HSA-5244582)
MeR30-HIST1H2AG [nucleoplasm]
(R-HSA-5244560)
Me2aR4-HIST1H2AG [nucleoplasm]
(R-HSA-5244587)
MeR4-HIST1H2AG [nucleoplasm]
(R-HSA-5244623)
Me2aR12-HIST1H2AG [nucleoplasm]
(R-HSA-5229305)
MeR12-HIST1H2AG [nucleoplasm]
(R-HSA-5229206)
HIST1H2AG [nucleoplasm]
(R-HSA-212084)
0.527
2
UniProt:O15212 PFDN6
1
PFDN6 [cytosol]
(R-HSA-379547)
0.527
2
UniProt:Q9ULU4 PKCB1
0.527
2
UniProt:Q92618 ZN516
0.527
2
UniProt:Q9P281 BAHC1
0.527
2
UniProt:Q96KQ7-2 EHMT2
0.527
2
UniProt:Q96KM6 Z512B
0.527
2
UniProt:O00629 KPNA4
2
KPNA4 [cytosol]
(R-HSA-1176066)
KPNA4 [nucleoplasm]
(R-HSA-1176058)
0.527
2
UniProt:Q8N1G0 ZN687
0.527
2
UniProt:O75530 EED
1
EED [nucleoplasm]
(R-HSA-212278)
0.527
3
UniProt:O75461 E2F6
2
p-S12-E2F6 [nucleoplasm]
(R-HSA-9007536)
E2F6 [nucleoplasm]
(R-HSA-8953089)
0.527
2
UniProt:Q14186 TFDP1
1
TFDP1 [nucleoplasm]
(R-HSA-68652)
0.527
2
UniProt:Q9BYE7 PCGF6
1
PCGF6 [nucleoplasm]
(R-HSA-8953572)
0.527
2
UniProt:Q9H160 ING2
2
ING2 [nucleoplasm]
(R-HSA-3215167)
SUMO1-K195-ING2 [nucleoplasm]
(R-HSA-4086075)
0.527
2
UniProt:Q96K83 ZNF521
1
ZNF521 [nucleoplasm]
(R-HSA-3222324)
0.527
2
UniProt:P43355 MAGA1
0.524
2
UniProt:Q92841-4 DDX17
0.524
3
UniProt:O00422 SAP18
1
SAP18 [nucleoplasm]
(R-HSA-351694)
0.524
2
UniProt:P03129 VE7
0.524
2
UniProt:Q66K89 E4F1
0.524
3
UniProt:P29128 ICP0
0.524
2
UniProt:P06748 NPM1
5
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [cytosol]
(R-HSA-3008211)
NPM1 [nucleoplasm]
(R-HSA-606320)
SUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
SUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.524
2
UniProt:Q9UIS9 MBD1
2
MBD1 [nucleoplasm]
(R-HSA-417134)
SUMO1-K499,K538-MBD1 [nucleoplasm]
(R-HSA-4090331)
0.524
2
UniProt:O43463 SUV39H1
1
SUV39H1 [nucleoplasm]
(R-HSA-427517)
0.524
3
UniProt:P51858 HDGF
1
HDGF [nucleoplasm]
(R-HSA-535593)
0.512
4
UniProt:Q92949 FOXJ1
0.508
2
IntAct:EBI-2694074 MDM2
0.499
2
UniProt:Q15466 NR0B2
1
NR0B2 [nucleoplasm]
(R-HSA-376312)
0.499
2
UniProt:Q99684 GFI1
1
GFI1 [nucleoplasm]
(R-HSA-2980932)
0.499
4
UniProt:P51610 HCFC1
2
K48polyUb,K63polyUb-HCFC1 [nucleoplasm]
(R-HSA-5690821)
HCFC1 [nucleoplasm]
(R-HSA-1592209)
0.499
2
UniProt:Q9UER7 DAXX
13
DAXX L98Vfs*13 [nucleoplasm]
(R-HSA-9673102)
SUMO1-K630,K631-DAXX [nucleoplasm]
(R-HSA-4086086)
DAXX R48Vfs*93 [nucleoplasm]
(R-HSA-9673103)
DAXX C74* [nucleoplasm]
(R-HSA-9673096)
DAXX S138* [nucleoplasm]
(R-HSA-9673081)
DAXX H26Tfs*118 [nucleoplasm]
(R-HSA-9673114)
DAXX E104* [nucleoplasm]
(R-HSA-9673078)
DAXX E72Nfs*72 [nucleoplasm]
(R-HSA-9673110)
DAXX C106* [nucleoplasm]
(R-HSA-9673079)
DAXX A103Sfs*40 [nucleoplasm]
(R-HSA-9673121)
DAXX K56* [nucleoplasm]
(R-HSA-9673089)
DAXX A36Qfs*108 [nucleoplasm]
(R-HSA-9673105)
DAXX [nucleoplasm]
(R-HSA-3222068)
0.499
2
UniProt:Q13227 GPS2
1
GPS2 [nucleoplasm]
(R-HSA-351642)
0.499
2
UniProt:A4PIW0 A4PIW0
0.462
3
UniProt:P23771 GATA3
2
PolyUb-GATA3 [nucleoplasm]
(R-HSA-6783009)
GATA3 [nucleoplasm]
(R-HSA-996768)
0.462
4
UniProt:P46531 NOTCH1
60
NOTCH1 I1680N S2 cleavage fragment [extracellular region]
(R-HSA-2730744)
NOTCH1 L1678P S2 cleavage fragment [extracellular region]
(R-HSA-2730745)
NOTCH1 I1718T S2 cleavage fragment [extracellular region]
(R-HSA-2730757)
NOTCH1 A1701P S2 cleavage fragment [plasma membrane]
(R-HSA-2730742)
NOTCH1 V1676D S2 cleavage fragment [extracellular region]
(R-HSA-2730755)
NOTCH1 I1680N Transmembrane Fragment [plasma membrane]
(R-HSA-2684869)
NOTCH1 I1718T Transmembrane Fragment [plasma membrane]
(R-HSA-2684881)
NOTCH1 I1616T Extracellular Fragment [extracellular region]
(R-HSA-2684866)
NOTCH1 L1596H Extracellular Fragment [extracellular region]
(R-HSA-2684853)
NOTCH1 L1678P Transmembrane Fragment [plasma membrane]
(R-HSA-1485591)
NOTCH1 A1701P Transmembrane Fragment [plasma membrane]
(R-HSA-1485585)
NOTCH1 I1616N Extracellular Fragment [extracellular region]
(R-HSA-2684862)
NOTCH1 L1593P Extracellular Fragment [extracellular region]
(R-HSA-1485584)
NOTCH1 R1598P Extracellular Fragment [extracellular region]
(R-HSA-1485592)
NOTCH1 V1576E Extracellular Fragment [extracellular region]
(R-HSA-2684852)
NOTCH1 V1676D Transmembrane Fragment [plasma membrane]
(R-HSA-2684874)
NOTCH1 F1592S Extracellular Fragment [extracellular region]
(R-HSA-2684847)
NOTCH1 L1574Q Extracellular Fragment [extracellular region]
(R-HSA-2691203)
p-NICD1 Q2440* [nucleoplasm]
(R-HSA-2902207)
p-NICD1 Q2395* [nucleoplasm]
(R-HSA-2902205)
p-NICD1 P2514Rfs*4 [nucleoplasm]
(R-HSA-2159809)
p-NICD1 P2474Afs*4 [nucleoplasm]
(R-HSA-2902204)
NOTCH1 L1574P Extracellular Fragment [extracellular region]
(R-HSA-1485582)
NOTCH1 L1600P Extracellular Fragment [extracellular region]
(R-HSA-2681764)
NEXT1 P2474Afs*4 [plasma membrane]
(R-HSA-2902194)
NEXT1 Q2395* [plasma membrane]
(R-HSA-2902192)
NEXT1 Q2440* [plasma membrane]
(R-HSA-2902196)
NEXT1 P2514Rfs*4 [plasma membrane]
(R-HSA-2768989)
NICD1 Q2395* [cytosol]
(R-HSA-2902195)
NICD1 P2514Rfs*4 [cytosol]
(R-HSA-2768996)
NICD1 P2474Afs*4 [cytosol]
(R-HSA-2902193)
NICD1 Q2440* [cytosol]
(R-HSA-2902191)
NICD1 P2514Rfs*4 [nucleoplasm]
(R-HSA-2769013)
NICD1 P2474Afs*4 [nucleoplasm]
(R-HSA-2902208)
NICD1 Q2395* [nucleoplasm]
(R-HSA-2902201)
NICD1 Q2440* [nucleoplasm]
(R-HSA-2902200)
NOTCH1 P2514Rfs*4 Transmembrane Fragment [plasma membrane]
(R-HSA-2768982)
NOTCH1 Q2395* Transmembrane Fragment [plasma membrane]
(R-HSA-1485596)
NOTCH1 Q2440* Transmembrane Fragment [plasma membrane]
(R-HSA-1485602)
NOTCH1 P2474Afs*4 Transmembrane Fragment [plasma membrane]
(R-HSA-2894873)
NOTCH1 t(7;9)(NOTCH1:M1580_K2555) extracellular fragment [extracellular region]
(R-HSA-2220929)
p-NICD1 [nucleoplasm]
(R-HSA-1604444)
Glc,GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane]
(R-HSA-1911426)
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane]
(R-HSA-1911415)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane]
(R-HSA-1911503)
FRINGE-modified NOTCH1 Extracellular Fragment (NECD1) [Golgi membrane]
(R-HSA-1911511)
Pre-NOTCH1 [endoplasmic reticulum membrane]
(R-HSA-157024)
17xFucT-2xFucS-NOTCH1(19-2555) [endoplasmic reticulum membrane]
(R-HSA-1467396)
19xFucT-14xGlcS-2xFucS-NOTCH1(19-2555) [endoplasmic reticulum membrane]
(R-HSA-1467425)
17xFucT-14xGlcS-2xFucS-NOTCH1(19-2555) [Golgi membrane]
(R-HSA-1472872)
NOTCH1(1665-2555) [Golgi membrane]
(R-HSA-157092)
17xFucT-14xGlcS-2xFucS-NOTCH1(19-1664) [Golgi membrane]
(R-HSA-1983679)
FRINGE-modified NOTCH1 Extracellular Fragment (NECD1) [plasma membrane]
(R-HSA-1911512)
NOTCH1(1665-2555) [plasma membrane]
(R-HSA-157239)
19xFucT-16xGlcS-2xFucS-NOTCH1(19-1664) [extracellular region]
(R-HSA-1983670)
NOTCH1(1665-1720) [extracellular region]
(R-HSA-157654)
NOTCH1(1721-1753) [plasma membrane]
(R-HSA-157656)
NEXT1 [plasma membrane]
(R-HSA-157200)
NICD1 [cytosol]
(R-HSA-157634)
NICD1 [nucleoplasm]
(R-HSA-157939)
0.462
2
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