The scaffolding adapter GAB2 plays a role in KIT dependent PI3K/AKT activation. GAB2 interacts with KIT indirectly via the adapter protein GRB2 which is bound to KIT on phosphorylated Y703 and Y936 (Sun et al. 2008, Yu et al. 2006).
Sun, J, Pedersen, M, Rönnstrand, L
Yu, M, Luo, J, Yang, W, Wang, Y, Mizuki, M, Kanakura, Y, Besmer, P, Neel, BG, Gu, H
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