Reactome | YWHAZ [cytosol]

YWHAZ [cytosol]

Stable Identifier

R-HSA-206099

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

14-3-3 zeta

Locations in the PathwayBrowser for interactor UniProt:Q6WCQ1 MPRIP

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External Reference Information

External Reference

UniProt:P63104 YWHAZ

Gene Names

YWHAZ

Chain

chain:1-245

Reference Genes

BioGPS Gene:7534 YWHAZ

COSMIC (genes):YWHAZ YWHAZ

CTD Gene:7534 YWHAZ

dbSNP Gene:7534 YWHAZ

ENSEMBL:ENSG00000164924 YWHAZ

HGNC:12855 YWHAZ

KEGG Gene (Homo sapiens):7534 YWHAZ

Monarch:7534 YWHAZ

NCBI Gene:7534 YWHAZ

OMIM:601288 YWHAZ

UCSC:P63104 YWHAZ

Reference Transcript

Other Identifiers

0003140048

0003140114

11756181_x_at

11758667_x_at

11758711_x_at

11758750_x_at

11758751_at

11758752_x_at

1235_at

1556496_a_at

17079711

17120418

200638_s_at

200639_s_at

200640_at

200641_s_at

214848_at

2574516

2574517

2924960

3146891

3146893

3146895

3146897

3146899

3146900

3146901

3146902

3146903

3146904

3146905

3146906

3146911

3146912

3146913

3146930

3146931

3146933

3146939

3146940

3146941

3146942

3146943

3146944

3146950

3146951

3146952

3146953

3146954

3146955

3204097

3204098

3238808

3238818

3238820

3262898

34642_at

36760_at

3694476

3749823

4005925

4005976

55272_at

7534

8152096

A_19_P00802601

A_24_P209571

A_24_P532478

GE548889

GE58115

GE59443

GE80033

GO:0003674

GO:0003723

GO:0004497

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005829

GO:0005925

GO:0006464

GO:0006468

GO:0006605

GO:0006810

GO:0006950

GO:0007005

GO:0007165

GO:0008039

GO:0008134

GO:0008150

GO:0008219

GO:0009056

GO:0010941

GO:0015031

GO:0016491

GO:0019221

GO:0019899

GO:0019901

GO:0019904

GO:0021700

GO:0022607

GO:0030154

GO:0030168

GO:0031410

GO:0031625

GO:0031982

GO:0034330

GO:0034641

GO:0034655

GO:0042470

GO:0042802

GO:0043066

GO:0043226

GO:0043488

GO:0044325

GO:0045296

GO:0048856

GO:0051683

GO:0055114

GO:0061024

GO:0070062

GO:0070372

GO:0072562

GO:0090128

GO:0090168

GO:0098686

GO:0098978

GO:1900740

Hs.71848.0.S1_3p_at

Hs2.58429.1.S1_3p_s_at

ILMN_1669286

ILMN_1801928

M86400_at

PH_hs_0040263

TC08001485.hg

TC08002448.hg

TC08002449.hg

TC08002451.hg

TC10000164.hg

U79277_at

g13177678_3p_a_at

g4507952_3p_a_at

g899458_3p_a_at

Participant Of

hasMember

14-3-3 beta, zeta [cytosol]

input

p-S585-IL3RB binds 14-3-3 proteins

hasComponent

Other forms of this molecule

YWHAZ [nucleoplasm]

Inferred To

Homologues of YWHAQ [cytosol] (Caenorhabditis elegans)

14-3-3zeta [cytosol] (Drosophila melanogaster)

par-5 [cytosol] (Caenorhabditis elegans)

ywhabl [cytosol] (Danio rerio)

YWHAZ [cytosol] (Bos taurus)

YWHAZ [cytosol] (Canis familiaris)

YWHAZ [cytosol] (Gallus gallus)

YWHAZ [cytosol] (Plasmodium falciparum)

YWHAZ [cytosol] (Sus scrofa)

Ywhaz [cytosol] (Mus musculus)

Ywhaz [cytosol] (Rattus norvegicus)

ywhaz [cytosol] (Xenopus tropicalis)

ftt-2 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001129174.1, NP_001129172.1, XP_016869299.1, NP_663723.1, XP_005251120.1, XP_016869300.1, XP_005251118.1, NP_001129173.1, NP_001129171.1, NP_003397.1

OpenTargets

ENSG00000164924

HPA

ENSG00000164924-YWHAZ

GeneCards

P63104

Ensembl

ENSP00000398599, ENST00000457309, ENST00000522542, ENSP00000379281, ENSP00000379286, ENSP00000395114, ENST00000353245, ENST00000419477, ENSG00000164924, ENSP00000379283, ENST00000395956, ENST00000395958, ENST00000395953, ENST00000395957, ENST00000395951, ENSP00000379288, ENSP00000379287, ENSP00000309503, ENSP00000430072

PRO

P63104

HMDB Protein

HMDBP02552

PDB

6FNC, 5M37, 6FNB, 6Q0K, 6EWW, 6EF5, 3NKX, 2C1J, 4WRQ, 4BG6, 1IB1, 3CU8, 2C1N, 5XY9, 4N7G, 5JM4, 6FNA, 5M35, 4FJ3, 4N7Y, 5D2D, 5WXN, 6F09, 5M36, 6F08, 6RLZ, 5ULO, 4HKC, 6EJL, 1QJA, 5J31, 1QJB, 2O02, 6FN9, 3RDH, 4N84, 5D3F, 5NAS, 6U2H, 5EWZ, 2WH0, 4ZDR, 4IHL, 5EXA

Interactors (153)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04049 RAF1	54	p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) RAF1 [cytosol] (R-HSA-167205) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094) p-S621-RAF1 D486G [cytosol] (R-HSA-9656085) p-S621-RAF1 T491R [cytosol] (R-HSA-9656145) p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol] (R-HSA-9656026) p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol] (R-HSA-9656070) p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol] (R-HSA-9656035) p-S338,Y341,S494,S621-RAF1 T491I [cytosol] (R-HSA-9656019) p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol] (R-HSA-9656029) p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol] (R-HSA-9656031) p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol] (R-HSA-9656023) p-S338,Y341,S494,S621 RAF1 T491R [cytosol] (R-HSA-9656017) p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol] (R-HSA-9656062) p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol] (R-HSA-9656041) p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol] (R-HSA-9656058) p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol] (R-HSA-9656043) p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol] (R-HSA-9656053) p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol] (R-HSA-9656037) p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol] (R-HSA-9656050) p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol] (R-HSA-9656067) p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol] (R-HSA-9656077) p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol] (R-HSA-9656047) p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol] (R-HSA-9656056) p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol] (R-HSA-9656074) p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol] (R-HSA-9656080) p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol] (R-HSA-9656065) hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S621-RAF1 [plasma membrane] (R-HSA-206222) p-Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5675420) p-S259,S621-RAF1 [cytosol] (R-HSA-109786) p-S621-RAF1 [cytosol] (R-HSA-206028) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-HSA-5672664)	0.957	18
UniProt:P30305 CDC25B	3	CDC25B [cytosol] (R-HSA-157412) p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644) CDC25B [nucleoplasm] (R-HSA-69734)	0.924	10
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.907	11
UniProt:P49815 TSC2	4	p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) TSC2 [cytosol] (R-HSA-2980548) p-S1387-TSC2 [cytosol] (R-HSA-3132769)	0.903	10
UniProt:P15056 BRAF	68	BRAF-MACF1fusion [cytosol] (R-HSA-6802402) p-S,T-BRAF [cytosol] (R-HSA-169856) p-BRAF-MACF1 fusion [cytosol] (R-HSA-6802536) BRAF [cytosol] (R-HSA-167224) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620) BRAF T244P [cytosol] (R-HSA-9651165) BRAF G469R [cytosol] (R-HSA-9648621) BRAF L597R [cytosol] (R-HSA-9648617) BRAF G469E [cytosol] (R-HSA-9648618) BRAF L597Q [cytosol] (R-HSA-9648619) BRAF G466A [cytosol] (R-HSA-9648613) BRAF G466V [cytosol] (R-HSA-9648838) BRAF N581S [cytosol] (R-HSA-9648850) BRAF G464V [cytosol] (R-HSA-9648611) p-BRAF L597V [plasma membrane] (R-HSA-8936647) p-BRAF L505H [plasma membrane] (R-HSA-9648862) p-BRAF G464E [plasma membrane] (R-HSA-8936645) p-BRAF F595L [plasma membrane] (R-HSA-8936641) p-BRAF A246P [plasma membrane] (R-HSA-9651188) p-BRAF E586K [plasma membrane] (R-HSA-8936639) p-BRAF N581D [plasma membrane] (R-HSA-9651191) p-BRAF V600K [plasma membrane] (R-HSA-8936651) p-BRAF G464V [plasma membrane] (R-HSA-9648633) p-BRAF T244P [plasma membrane] (R-HSA-9651194) p-BRAF G469E [plasma membrane] (R-HSA-9648634) p-BRAF G466V [plasma membrane] (R-HSA-9648859) p-BRAF G469V [plasma membrane] (R-HSA-9648628) p-BRAF G466A [plasma membrane] (R-HSA-9648629) p-BRAF L597Q [plasma membrane] (R-HSA-9648630) p-BRAF L597R [plasma membrane] (R-HSA-9648631) p-BRAF N581S [plasma membrane] (R-HSA-9648866) p-BRAF G469R [plasma membrane] (R-HSA-9648627) BRAF 599dupT [cytosol] (R-HSA-6802281) BRAF G534R [cytosol] (R-HSA-9651134) BRAF S467A [cytosol] (R-HSA-9651161) BRAF K601N [cytosol] (R-HSA-9648857) BRAF G469A [cytosol] (R-HSA-6802381) BRAF L485F [cytosol] (R-HSA-9651147) BRAF Q257R [cytosol] (R-HSA-9651157) BRAF K499E [cytosol] (R-HSA-9651142) BRAF V600E [cytosol] (R-HSA-6802498) BRAF K601E [cytosol] (R-HSA-9648833) BRAF V600E V169_M438del [cytosol] (R-HSA-6802489) BRAF V600E V47_D380del [cytosol] (R-HSA-6802491) BRAF V600E V47_M438del [cytosol] (R-HSA-6802495) V600E BRAF V169_D380del [cytosol] (R-HSA-6802486) p-S445,S729-BRAF [plasma membrane] (R-HSA-8933622) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S365,S445,S729 BRAF [cytosol] (R-HSA-5672667) p-S445,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679) p-S445,S729-BRAF [cytosol] (R-HSA-5672673) p-S445,T599,S602,S729 BRAF [cytosol] (R-HSA-5672676)	0.899	10
UniProt:P27448 MARK3	1	MARK3 [cytosol] (R-HSA-5672591)	0.893	11
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.864	9
UniProt:Q92934 BAD	4	p-S99-BAD [cytosol] (R-HSA-198335) BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S128-BAD [cytosol] (R-HSA-217297)	0.864	8
UniProt:Q7KZI7 MARK2			0.845	7
UniProt:P54253 ATX1			0.845	12
UniProt:Q02241 KIF23	3	p-S904,S905-KIF23 [nucleoplasm] (R-HSA-156695) KIF23 [nucleoplasm] (R-HSA-156709) KIF23 [cytosol] (R-HSA-1015863)	0.836	6
UniProt:P56524 HDAC4	3	SUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) SUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029) HDAC4 [nucleoplasm] (R-HSA-351581)	0.809	6
UniProt:P46937 YAP1	7	p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-5S-YAP1 [cytosol] (R-HSA-2028554) YAP1 [nucleoplasm] (R-HSA-1253322) YAP1 [cytosol] (R-HSA-1253345)	0.803	9
UniProt:P10398 ARAF	4	p-S299,S302,T452,T455,S576 ARAF [plasma membrane] (R-HSA-5672648) p-S299,S302,T452,T455,S576 ARAF [cytosol] (R-HSA-5672646) p-S576 ARAF [cytosol] (R-HSA-5672681) p-S214,S576 ARAF [cytosol] (R-HSA-5672639)	0.798	6
UniProt:P00533 EGFR	59	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334) p-6Y-EGFR T263P [plasma membrane] (R-HSA-1996336) p-6Y-EGFR G598V [plasma membrane] (R-HSA-1996339) p-6Y-EGFR R108K [plasma membrane] (R-HSA-1996338) p-6Y-EGFR A289T [plasma membrane] (R-HSA-1996341) p-6Y-EGFR G719C [plasma membrane] (R-HSA-1177530) p-6Y-EGFR A289D [plasma membrane] (R-HSA-1996340) p-6Y-EGFR G719A [plasma membrane] (R-HSA-1177528) EGFR L858R;T790M [plasma membrane] (R-HSA-1181386) EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1181399) EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996322) EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996325) EGFR M766_A767insASV [plasma membrane] (R-HSA-1996326) EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996317) EGFR L858R [plasma membrane] (R-HSA-1173212) EGFR G719S [plasma membrane] (R-HSA-1169418) EGFR E746_A750del [plasma membrane] (R-HSA-1181211) EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228010) EGFR A289V [plasma membrane] (R-HSA-1996321) EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228012) EGFR L747_T751del [plasma membrane] (R-HSA-1228015) EGFR A289D [plasma membrane] (R-HSA-1996327) EGFR L861Q [plasma membrane] (R-HSA-1177542) EGFR R108K [plasma membrane] (R-HSA-1996330) EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228034) EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228031) EGFR G719A [plasma membrane] (R-HSA-1177532) EGFR A289T [plasma membrane] (R-HSA-1996306) EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228025) EGFR G719C [plasma membrane] (R-HSA-1177531) EGFR T263P [plasma membrane] (R-HSA-1996315) EGFR G598V [plasma membrane] (R-HSA-1996314) EGFR L747_S752del [plasma membrane] (R-HSA-1228016) EGFR [endosome membrane] (R-HSA-9611160) p-4Y-EGFR [plasma membrane] (R-HSA-180287) p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane] (R-HSA-8864019) p-Y1086,Y1101-EGFR [plasma membrane] (R-HSA-179868) EGFR [plasma membrane] (R-HSA-179837) p-6Y-EGFR [plasma membrane] (R-HSA-179803)	0.772	6
UniProt:O96013 PAK4	1	PAK4 [cytosol] (R-HSA-428461)	0.77	4
UniProt:P40818 USP8	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.77	4
UniProt:P33176 KIF5B	1	KIF5B [cytosol] (R-HSA-265181)	0.77	4
UniProt:Q8WUI4 HDAC7	1	HDAC7 [nucleoplasm] (R-HSA-3004534)	0.744	4
UniProt:Q02156 PRKCE	2	p-T566,T710,S729-PRKCE [plasma membrane] (R-HSA-198260) PRKCE [cytosol] (R-HSA-58202)	0.729	7
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.725	7
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.725	5
UniProt:Q8TEW0 PARD3	3	PARD3 [cytosol] (R-HSA-419993) PARD3 [plasma membrane] (R-HSA-419980) PARD3 [cell junction] (R-HSA-2134481)	0.723	5
UniProt:P10636 MAPT	3	MAPT(2-421) [cytosol] (R-HSA-350628) MAPT(422-758) [cytosol] (R-HSA-350642) MAPT [cytosol] (R-HSA-201574)	0.723	8
UniProt:Q99683 MAP3K5	1	MAP3K5 [cytosol] (R-HSA-167709)	0.716	4
UniProt:P26045 PTPN3	3	p-S459 PTPN3 [cytosol] (R-HSA-8868111) PTPN3 [plasma membrane] (R-HSA-5490317) PTPN3 [cytosol] (R-HSA-8867650)	0.708	4
UniProt:Q6PKG0 LARP1			0.702	3
UniProt:Q9NYL2 M3K20			0.696	5
UniProt:P06733 ENO1	1	ENO1 [cytosol] (R-HSA-71437)	0.692	3
UniProt:Q9NSK0 KLC4	1	KLC4 [cytosol] (R-HSA-983244)	0.688	3
UniProt:O43524 FOXO3	9	p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) FOXO3 [cytosol] (R-HSA-5687032) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) FOXO3 [nucleoplasm] (R-HSA-199305) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413)	0.688	3
UniProt:Q86X27 RGPS2			0.688	4
UniProt:O95544 NADK	1	NADK [cytosol] (R-HSA-197282)	0.688	3
UniProt:Q5PRF9 SMAG2			0.688	3
UniProt:P25705 ATP5F1A	3	ATP5A1(1-553) [cytosol] (R-HSA-1267955) ATP5A1(1-553) [mitochondrial intermembrane space] (R-HSA-1267978) ATP5A1 [mitochondrial matrix] (R-HSA-164575)	0.688	4
UniProt:Q9P0K7 RAI14			0.688	3
UniProt:Q9H0B6 KLC2	1	KLC2 [cytosol] (R-HSA-983191)	0.688	3
UniProt:P04792 HSPB1	3	p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) HSPB1 [cytosol] (R-HSA-450563) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.678	4
UniProt:O95685 PPR3D			0.675	4
UniProt:P05783 KRT18	1	KRT18 [cytosol] (R-HSA-201582)	0.669	3
UniProt:Q92974 ARHGEF2	1	ARHGEF2 [cytosol] (R-HSA-195101)	0.669	3
UniProt:Q13625 TP53BP2	1	TP53BP2 [nucleoplasm] (R-HSA-6799780)	0.669	3
UniProt:Q9UQL6 HDAC5	1	HDAC5 [nucleoplasm] (R-HSA-3004533)	0.669	3
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.669	3
UniProt:Q9Y4H2 IRS2	4	IRS2 [cytosol] (R-HSA-57528) IRS2 [plasma membrane] (R-HSA-2428927) p-Y-IRS2 [cytosol] (R-HSA-74774) p-Y-IRS2 [plasma membrane] (R-HSA-198334)	0.669	3
UniProt:P23528 CFL1	3	p-S3-CFL1 [cytosol] (R-HSA-399813) CFL1 [cytosol] (R-HSA-350751) CFL1 [extracellular region] (R-HSA-350747)	0.656	3
UniProt:P61587 RND3			0.655	11
UniProt:O14744 PRMT5	3	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609)	0.646	3
UniProt:Q9P0L2 MARK1			0.643	3
UniProt:P68431 H3C1	59	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) HIST1H3A [extracellular region] (R-HSA-977570) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) AcK19-HIST1H3A [nucleoplasm] (R-HSA-4568761) AcK5-HIST1H3A [nucleoplasm] (R-HSA-4568751) AcK24-HIST1H3A [nucleoplasm] (R-HSA-4568754) AcK15-HIST1H3A [nucleoplasm] (R-HSA-4568743) Ack15-HIST1H3A [nucleoplasm] (R-HSA-4549217) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5229050) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4754188) Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4754169) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791) Me3K80-HIST1H3A [nucleoplasm] (R-HSA-5649795) Me2K80-HIST1H3A [nucleoplasm] (R-HSA-5649768) Me3K37-HIST1H3A [nucleoplasm] (R-HSA-5638160) Me2K37-HIST1H3A [nucleoplasm] (R-HSA-4722125) MeK10-HIST1H3A [nucleoplasm] (R-HSA-212105) MeK28-HIST1H3A [nucleoplasm] (R-HSA-5638327) MeK-10-HIST1H3A [cytosol] (R-HSA-8943830) HIST1H3A [cytosol] (R-HSA-8943829) Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-5244526) MeK5-HIST1H3A [nucleoplasm] (R-HSA-4687016) Cit27-HIST1H3A [nucleoplasm] (R-HSA-5246532) Cit3-HIST1H3A [nucleoplasm] (R-HSA-5246544) Cit9-HIST1H3A [nucleoplasm] (R-HSA-5246530) Cit18-HIST1H3A [nucleoplasm] (R-HSA-5246534) MeR18-HIST1H3A [nucleoplasm] (R-HSA-5229059) MeR3-HIST1H3A [nucleoplasm] (R-HSA-5244529) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5244801) MeR9-HIST1H3A [nucleoplasm] (R-HSA-5244806) Ack10-HIST1H3A [nucleoplasm] (R-HSA-4568939) Me2K10-HIST1H3A [nucleoplasm] (R-HSA-427378) Me2K5,Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-8936572) p-T12, Me2K-10-HIST1H3A [nucleoplasm] (R-HSA-5625790) p-T12-HIST1H3A [nucleoplasm] (R-HSA-5625872) p-T12,MeK-10-HIST1H3A [nucleoplasm] (R-HSA-5625859) p-T12, Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-5625757) Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-427734) Me3K5-HIST1H3A [nucleoplasm] (R-HSA-1214186) HIST1H3A [nucleoplasm] (R-HSA-212070) Me3K-28-HIST1H3A [nucleoplasm] (R-HSA-212220) Me2K5-HIST1H3A [nucleoplasm] (R-HSA-1214170)	0.643	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.643	4
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.643	5
UniProt:Q9Y3M2 CBY1	3	CBY1 [nucleoplasm] (R-HSA-3769210) pS20-CBY1 [nucleoplasm] (R-HSA-3769356) pS20-CBY1 [cytosol] (R-HSA-3769354)	0.643	3
UniProt:Q9UQC2 GAB2	4	p-Y452,Y476,Y584-GAB2 [cytosol] (R-HSA-2685615) p-Y-GAB2 [cytosol] (R-HSA-912529) GAB2 [cytosol] (R-HSA-508239) p-5Y-GAB2 [cytosol] (R-HSA-8855574)	0.643	4
UniProt:Q61337 Bad	6	Bad [mitochondrial outer membrane] (R-MMU-114242) phospho-Bad [cytosol] (R-MMU-217297) p-S136-Bad [cytosol] (R-MMU-3139049) Bad [cytosol] (R-MMU-3139043) phospho-Bad [cytosol] (R-MMU-198335) Bad [cytosol] (R-MMU-50662)	0.643	3
UniProt:Q01113 IL9R	2	p-Y116-IL9R [plasma membrane] (R-HSA-8985904) IL9R [plasma membrane] (R-HSA-449790)	0.635	5
UniProt:P67828 KC1A			0.632	4
UniProt:Q9P0K1 ADAM22	1	ADAM22 [plasma membrane] (R-HSA-5678678)	0.626	5
UniProt:P00519 ABL1	5	p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) ABL1 [cytosol] (R-HSA-375987) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) ABL1 [nucleoplasm] (R-HSA-5686579) p-Y226,Y393-ABL1 [cytosol] (R-HSA-8942610)	0.623	3
UniProt:P54256-2 HAP1			0.619	4
UniProt:P10636-3 MAPT			0.618	9
UniProt:Q15831 STK11	2	STK11 [nucleoplasm] (R-HSA-164119) STK11 [cytosol] (R-HSA-380954)	0.61	6
UniProt:P30793 GCH1	1	GCH1 [cytosol] (R-HSA-1474127)	0.602	4
UniProt:Q29495 SNAT			0.602	3
UniProt:Q16890 TPD52L1	2	TPD52L1 [cytoplasmic vesicle lumen] (R-HSA-434220) TPD52L1 [Golgi lumen] (R-HSA-434331)	0.593	3
UniProt:P84198 VIME			0.591	5
UniProt:Q96F86 EDC3	1	EDC3 [cytosol] (R-HSA-429997)	0.589	2
UniProt:Q9Y2J2 EPB41L3	1	EPB41L3 [cytosol] (R-HSA-6797563)	0.589	2
UniProt:O00273 DFFA	6	DFFA(1-?) [nucleoplasm] (R-HSA-211228) DFFA [cytosol] (R-HSA-211221) DFFA(225-331) [nucleoplasm] (R-HSA-211188) DFFA(118-224) [nucleoplasm] (R-HSA-211205) DFFA(118-331) [nucleoplasm] (R-HSA-211199) DFFA(1-117) [nucleoplasm] (R-HSA-211185)	0.589	2
UniProt:Q14978 NOLC1			0.589	2
UniProt:Q13310 PABP4			0.589	2
UniProt:P62995 TRA2B	1	TRA2B [nucleoplasm] (R-HSA-8850859)	0.589	2
UniProt:Q9UDY2 TJP2	4	TJP2 [nucleoplasm] (R-HSA-2064410) TJP2 [cytosol] (R-HSA-2064412) TJP2 [plasma membrane] (R-HSA-351862) TJP2(?-?) [plasma membrane] (R-HSA-351897)	0.589	2
UniProt:Q9P0K1-3 ADAM22			0.581	3
UniProt:P57059 SIK1	1	SIK1 [nucleoplasm] (R-HSA-5656504)	0.577	4
UniProt:P16104 H2AX	7	Me2sR4-H2AFX [nucleoplasm] (R-HSA-5218317) H2AFX [extracellular region] (R-HSA-977583) K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm] (R-HSA-5682847) p-S140-H2AFX [nucleoplasm] (R-HSA-75170) p-S140,Y143-H2AFX [nucleoplasm] (R-HSA-5683953) p-Y143-H2AFX [nucleoplasm] (R-HSA-5683942) H2AFX [nucleoplasm] (R-HSA-56151)	0.577	6
UniProt:Q9Y2K2 SIK3			0.577	5
UniProt:O94875 SRBS2			0.573	2
UniProt:P55072 VCP	8	VCP [endoplasmic reticulum membrane] (R-HSA-8943105) Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [nucleoplasm] (R-HSA-5643745) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [extracellular region] (R-HSA-6806191) VCP [secretory granule lumen] (R-HSA-6801039) VCP [cytosol] (R-HSA-1181251)	0.573	2
UniProt:Q5T5U3 ARHGAP21	1	ARHGAP21 [cytosol] (R-HSA-8873918)	0.564	2
UniProt:O15151 MDM4	5	PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] (R-HSA-6804938) PolyUb-MDM4 [nucleoplasm] (R-HSA-6782502) p-S346,S367,S403-MDM4 [nucleoplasm] (R-HSA-349441) p-S403-MDM4 [nucleoplasm] (R-HSA-349461) MDM4 [nucleoplasm] (R-HSA-349430)	0.564	2
UniProt:Q71U36 TUBA1A	9	Ac K40 TUBA1A [axonemal microtubule] (R-HSA-5624852) AcK-TUBA1A [cytosol] (R-HSA-5618312) TUBA1A folding intermediate [cytosol] (R-HSA-392805) TUBA1A unfolded [cytosol] (R-HSA-392767) L-isoglutamyl polyglycyl-TUBA1A [cytosol] (R-HSA-8867428) TUBA1A [cytosol] (R-HSA-191689) TUBA1A [axonemal microtubule] (R-HSA-5610433) TUBA1A(1-450) [cytosol] (R-HSA-8955577) Polyglutamyl-TUBA1A [cytosol] (R-HSA-8867408)	0.564	4
UniProt:Q7L8J4 3BP5L			0.564	2
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.564	3
UniProt:Q9P2M7 CGN	1	CGN [cell junction] (R-HSA-2134478)	0.564	3
UniProt:Q16658 FSCN1	1	FSCN1 [cytosol] (R-HSA-6789835)	0.564	3
UniProt:O60343 TBC1D4	2	TBC1D4 [cytoplasmic vesicle membrane] (R-HSA-1445122) p-5S,T642-TBC1D4 [cytoplasmic vesicle membrane] (R-HSA-1445101)	0.564	2
UniProt:Q6ICG6 K0930			0.564	2
UniProt:P62805 H4C1	19	SUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) HIST1H4A [extracellular region] (R-HSA-977569) SUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-4568749) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) MeK-HIST1H4A [nucleoplasm] (R-HSA-2172676) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652)	0.564	3
UniProt:O75044 SRGAP2	1	SRGAP2 [cytosol] (R-HSA-195131)	0.564	2
UniProt:Q7Z401 DENND4A	1	DENND4A [cytosol] (R-HSA-8876072)	0.564	2
UniProt:Q9Y4D8 HECD4			0.564	2
UniProt:Q99759 MAP3K3	1	MAP3K3 [cytosol] (R-HSA-507725)	0.564	2
UniProt:P31327 CPS1	1	CPS1 [mitochondrial matrix] (R-HSA-70544)	0.564	2
UniProt:Q12802 AKAP13	1	AKAP13 [cytosol] (R-HSA-2975983)	0.564	2
UniProt:Q7Z6B7 SRGAP1	1	SRGAP1 [cytosol] (R-HSA-428453)	0.564	2
UniProt:P08670 VIM	11	VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264) VIM(430-466) [cytosol] (R-HSA-350316) VIM(2-429) [cytosol] (R-HSA-350317) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-259) [cytosol] (R-HSA-350323) VIM [cytosol] (R-HSA-201600) Vimentin [late endosome lumen] (R-HSA-9660019) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [cytosol] (R-HSA-9646687) Vimentin [lysosomal lumen] (R-HSA-9659977)	0.564	2
UniProt:O60825 PFKFB2	1	PFKFB2 [cytosol] (R-HSA-71790)	0.564	2
UniProt:P0C0S8 H2AC11	11	Ub-HIST1H2AG [nucleoplasm] (R-HSA-6782508) K63polyUb-HIST1H2AG [nucleoplasm] (R-HSA-6783237) Ack6-HIST1H2AG [nucleoplasm] (R-HSA-4568595) Ack-HIST1H2AG [nucleoplasm] (R-HSA-4551311) Me2aR30-HIST1H2AG [nucleoplasm] (R-HSA-5244582) MeR30-HIST1H2AG [nucleoplasm] (R-HSA-5244560) Me2aR4-HIST1H2AG [nucleoplasm] (R-HSA-5244587) MeR4-HIST1H2AG [nucleoplasm] (R-HSA-5244623) Me2aR12-HIST1H2AG [nucleoplasm] (R-HSA-5229305) MeR12-HIST1H2AG [nucleoplasm] (R-HSA-5229206) HIST1H2AG [nucleoplasm] (R-HSA-212084)	0.564	2
UniProt:Q07866 KLC1	1	KLC1 [cytosol] (R-HSA-983284)	0.564	2
UniProt:O75592 MYCB2			0.564	2
UniProt:O00750 PIK3C2B	1	PIK3C2B [cytosol] (R-HSA-1604619)	0.564	2
UniProt:P23396 RPS3	2	RPS3 [cytosol] (R-HSA-72369) RPS3 [nucleoplasm] (R-HSA-6798714)	0.564	2
UniProt:O60292 SI1L3			0.564	2
UniProt:Q00537 CDK17			0.564	3
UniProt:P62158 CALM			0.564	2
UniProt:Q6WCQ1 MPRIP	2	p-MPRIP-RAF1 fusion [cytosol] (R-HSA-6802540) MPRIP-RAF1 fusion [cytosol] (R-HSA-6802406)	0.564	2
UniProt:Q6P597 KLC3	1	KLC3 [cytosol] (R-HSA-983232)	0.564	2
UniProt:Q5VV41 ARHGEF16	1	ARHGEF16 [cytosol] (R-HSA-2976623)	0.564	2
UniProt:P06748 NPM1	5	p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [cytosol] (R-HSA-3008211) NPM1 [nucleoplasm] (R-HSA-606320) SUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) SUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.564	2
UniProt:P60709 ACTB	5	Unfolded ACTB [cytosol] (R-HSA-390462) ACTB(1-375) [lysosomal membrane] (R-HSA-196160) ACTB(1-375) [cytosol] (R-HSA-201861) ACTB(1-375) [nucleoplasm] (R-HSA-3321990) ACTB(1-375) [plasma membrane] (R-HSA-196016)	0.564	3
UniProt:P04637 TP53	27	TP53 [cytosol] (R-HSA-8869337) Unfolded TP53 [cytosol] (R-HSA-6813797) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) SUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) Me2K-370,382-TP53 [nucleoplasm] (R-HSA-3222242) p-S15,S33,S46-TP53 [nucleoplasm] (R-HSA-6805268) p-S15,S392-TP53 [nucleoplasm] (R-HSA-3222015) p-T55-TP53 [nucleoplasm] (R-HSA-6805400) p-S15,S20,S392-TP53 [nucleoplasm] (R-HSA-6805053) p-S15,S20,S269,T284-TP53 [nucleoplasm] (R-HSA-6805133) p-S315-TP53 [nucleoplasm] (R-HSA-6805106) Ac-K120,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805656) Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805631) Ac-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-5628868) Me2-K373-TP53 [nucleoplasm] (R-HSA-6805759) MeK-370,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222226) p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (R-HSA-6804378) Me-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222124) Me1-K372,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805719) p-S15,S20,S46-TP53 [nucleoplasm] (R-HSA-6798369) p-S37-TP53 [nucleoplasm] (R-HSA-3239022) PolyUb,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6804446) PolyUb-TP53 [nucleoplasm] (R-HSA-6793679) PolyUb-TP53 [cytosol] (R-HSA-6793681) p-S15,S20-TP53 [nucleoplasm] (R-HSA-69683) p-S15-TP53 [nucleoplasm] (R-HSA-69507) TP53 [nucleoplasm] (R-HSA-69488)	0.564	2
UniProt:P06576 ATP5F1B	6	ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B [mitochondrial inner membrane] (R-HSA-1299441) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B [mitochondrial matrix] (R-HSA-164576)	0.564	2
UniProt:P02545 LMNA	3	LMNA-RAF1 fusion [cytosol] (R-HSA-6802399) LMNA(1-664) [nucleoplasm] (R-HSA-535479) p-LMNA-RAF1 fusion [cytosol] (R-HSA-6802537)	0.564	2
UniProt:P68104 EEF1A1	7	EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [lysosomal membrane] (R-HSA-9626022) EEF1A1 [secretory granule lumen] (R-HSA-6801479) EEF1A1 [extracellular region] (R-HSA-6806456) EEF1A1 [ficolin-1-rich granule lumen] (R-HSA-6801528) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) Me3K79-EEF1A1 [cytosol] (R-HSA-8932212)	0.564	2
UniProt:P07910 HNRNPC	2	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543)	0.564	2
UniProt:O14980 XPO1	2	XPO1 [nucleoplasm] (R-HSA-165529) XPO1 [cytosol] (R-HSA-165539)	0.564	2
UniProt:P10636-2 MAPT			0.558	2
UniProt:P36897 TGFBR1	13	p-4S,T185,T186-TGFBR1 W242* [plasma membrane] (R-HSA-3656504) Ub-TGFBR1 [plasma membrane] (R-HSA-8869461) p-4S,T185,T186-TGFBR1 P327Qfs8 [plasma membrane] (R-HSA-3656505) p-4S,T185,T186-TGFBR1 L354Nfs4 [plasma membrane] (R-HSA-3656506) p-4S,T185,T186-TGFBR1 R414* [plasma membrane] (R-HSA-3656508) p-4S,T185,T186-TGFBR1 D269_Q324del [plasma membrane] (R-HSA-3656509) TGFBR1 G52R [plasma membrane] (R-HSA-3656368) TGFBR1 C41Y [plasma membrane] (R-HSA-3656328) TGFBR1 N45S [plasma membrane] (R-HSA-3656348) TGFBR1 P83L [plasma membrane] (R-HSA-3656341) TGFBR1 P83S [plasma membrane] (R-HSA-3656326) TGFBR1 [plasma membrane] (R-HSA-170839) p-4S,T185,T186-TGFBR1 [plasma membrane] (R-HSA-170849)	0.556	4
UniProt:Q86Z20 CC125			0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q9Y4H4 GPSM3	1	GPSM3 [cytosol] (R-HSA-8949486)	0.556	5
UniProt:Q9NRI5 DISC1			0.553	3
UniProt:Q99459 CDC5L	1	CDC5L [nucleoplasm] (R-HSA-5420887)	0.553	2
UniProt:P60520 GABARAPL2	3	GABARAPL2(1-117) [cytosol] (R-HSA-5682641) GABARAPL2 [cytosol] (R-HSA-5671758) GABARAPL2 [autophagosome membrane] (R-HSA-5683633)	0.547	2
UniProt:O43896 KIF1C	1	KIF1C [cytosol] (R-HSA-8849365)	0.547	2
UniProt:P29172 TAU			0.544	2
UniProt:P30291 WEE1	3	p-WEE1 [nucleoplasm] (R-HSA-156491) p-S53-WEE1 [nucleoplasm] (R-HSA-156694) WEE1 [nucleoplasm] (R-HSA-69253)	0.544	3
UniProt:P30304 CDC25A	6	p-S123-CDC25A [nucleoplasm] (R-HSA-143488) CDC25A [nucleoplasm] (R-HSA-143487) CDC25A [cytosol] (R-HSA-157410) p-S123-CDC25A [cytosol] (R-HSA-69588) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634) PolyUb-CDC25A [cytosol] (R-HSA-6782810)	0.544	2
UniProt:Q6P6S3 BSPRY			0.543	3
UniProt:Q9H1R3 MYLK2			0.527	3
UniProt:Q6R327 RICTOR	1	RICTOR [cytosol] (R-HSA-198632)	0.527	2
UniProt:Q02750 MAP2K1	27	MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) MAP2K1 F53S [cytosol] (R-HSA-9652034) MAP2K1 D67N [cytosol] (R-HSA-9652016) MAP2K1 Q56P [cytosol] (R-HSA-9652064) MAP2K1 E203K [cytosol] (R-HSA-9652023) MAP2K1 V60E [cytosol] (R-HSA-9652067) MAP2K1 P124S [cytosol] (R-HSA-9652062) MAP2K1 Y130C [cytosol] (R-HSA-9652101) MAP2K1 C121S [cytosol] (R-HSA-9652013) MAP2K1 G128V [cytosol] (R-HSA-9652047) MAP2K1 F53L [cytosol] (R-HSA-9652031) MAP2K1 K57N [cytosol] (R-HSA-9652050) MAP2K1 K57T [cytosol] (R-HSA-9652052) MAP2K1 F53V [cytosol] (R-HSA-9652038) MAP2K1 D67Y [cytosol] (R-HSA-9652019) MAP2K1 G128D [cytosol] (R-HSA-9652043) MAP2K1 P124L [cytosol] (R-HSA-9652056) MAP2K1 F53Y [cytosol] (R-HSA-9652041) MAP2K1 E44_E57del [cytosol] (R-HSA-9652026) MAP2K1 P124Q [cytosol] (R-HSA-9652058) MAP2K1 F53C [cytosol] (R-HSA-9652028) p-S,218, S222,T292 MAP2K1 [cytosol] (R-HSA-5674490) MAP2K1 [cytosol] (R-HSA-59502) p-T286,T292-MAP2K1 [cytosol] (R-HSA-112374) p-S218,S222,T286,T292-MAP2K1 [cytosol] (R-HSA-112339) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.527	4
UniProt:P49796 RGS3	1	RGS3 [plasma membrane] (R-HSA-8849410)	0.527	2
UniProt:Q9Y2U5 M3K2			0.527	2
UniProt:Q8WYL5 SSH1			0.527	2
UniProt:P07101 TH	1	TH [cytosol] (R-HSA-2980863)	0.527	2
UniProt:Q7L804 RAB11FIP2	1	RAB11FIP2 [cytoplasmic vesicle membrane] (R-HSA-2028707)	0.527	2
UniProt:Q00536 CDK16			0.527	2
UniProt:Q86VP3 PACS2			0.527	2
UniProt:P31946-2 YWHAB			0.527	2
UniProt:Q12778 FOXO1	5	p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306) FOXO1 [nucleoplasm] (R-HSA-199300) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) p-S215 FOXO1 [nucleoplasm] (R-HSA-5692651)	0.527	3
UniProt:P29353 SHC1	5	p-Y427-SHC1 [cytosol] (R-HSA-74684) SHC1 [cytosol] (R-HSA-74680) p-Y349,Y350-SHC1 [cytosol] (R-HSA-180276) p-Y-SHC1 [cytosol] (R-HSA-162568) p-Y349,Y350,Y427-SHC1 [cytosol] (R-HSA-912321)	0.527	2
UniProt:P07359 GP1BA	1	GP1BA [plasma membrane] (R-HSA-55861)	0.527	2
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.527	3
UniProt:Q63767	4	phospho-Bcar1 [cytosol] (R-RNO-5218739) phospho-Bcar1 [cytosol] (R-RNO-372645) phospho-Bcar1 [cytosol] (R-RNO-8848723) Bcar1 [cytosol] (R-RNO-201625)	0.527	2
UniProt:Q9UQB8 BAIAP2	1	BAIAP2 [cytosol] (R-HSA-442574)	0.527	3
UniProt:P22681 CBL	39	CBL R420Q [cytosol] (R-HSA-9706186) CBL R420G [cytosol] (R-HSA-9706203) CBL Y371H [cytosol] (R-HSA-9706680) CBL H398Y [cytosol] (R-HSA-9706639) CBL P417A [cytosol] (R-HSA-9706636) CBL S376F [cytosol] (R-HSA-9706643) CBL del366-409 [cytosol] (R-HSA-9706179) CBL del366-477 [cytosol] (R-HSA-9706176) CBL R499L [cytosol] (R-HSA-9706678) CBL L380P [cytosol] (R-HSA-9706630) CBL L287R [cytosol] (R-HSA-9706693) CBL L380R [cytosol] (R-HSA-9706635) CBL G375P [cytosol] (R-HSA-9706219) CBL P417L [cytosol] (R-HSA-9706634) CBL H398Q [cytosol] (R-HSA-9706633) CBL P417R [cytosol] (R-HSA-9706632) CBL R499* [cytosol] (R-HSA-9706670) CBL H398R [cytosol] (R-HSA-9706638) CBL H398P [cytosol] (R-HSA-9706637) CBL G375fs16 [cytosol] (R-HSA-9706211) CBL R420 [cytosol] (R-HSA-9706208) CBL H398D [cytosol] (R-HSA-9706631) CBL Y371C [cytosol] (R-HSA-9706694) CBL G375S [cytosol] (R-HSA-9706214) CBL Y371D [cytosol] (R-HSA-9706687) CBL Y371S [cytosol] (R-HSA-9706674) CBL P417S [cytosol] (R-HSA-9706642) CBL H398N [cytosol] (R-HSA-9706641) CBL R420P [cytosol] (R-HSA-9706193) CBL Y371N [cytosol] (R-HSA-9706679) CBL R499Q [cytosol] (R-HSA-9706677) CBL R420L [cytosol] (R-HSA-9706197) CBL P417H [cytosol] (R-HSA-9706644) p-Y371-CBL [plasma membrane] (R-HSA-182923) p-Y-CBL [cytosol] (R-HSA-8875457) p-Y371-CBL [cytosol] (R-HSA-182940) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) CBL [cytosol] (R-HSA-112199)	0.527	2
UniProt:Q8NFH8-2 REPS2			0.524	2
UniProt:O00257-3 CBX4			0.499	2
UniProt:Q51451 Q51451			0.469	2
UniProt:Q6PJG9 LRFN4	1	SALM3 [plasma membrane] (R-HSA-197883)	0.462	3
UniProt:Q76353 Q76353			0.462	2

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