HS(6)-SDC2 [lysosomal lumen]

Stable Identifier
R-HSA-2090064
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
SDC2, HSPG, SDC2_HUMAN, Heparan sulfate proteoglycan core protein
Icon
HS(6)-SDC2 [lysosomal lumen] icon
HS(6)-SDC2 [lysosomal lumen] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P34741 SDC2
Gene Names
SDC2, HSPG1
Chain
signal peptide:1-18, chain:19-201
Reference Genes
BioGPS Gene:6383 SDC2
COSMIC (genes):SDC2 SDC2
CTD Gene:6383 SDC2
dbSNP Gene:6383 SDC2
ENSEMBL:ENSG00000169439 SDC2
HGNC:10659 SDC2
KEGG Gene (Homo sapiens):6383 SDC2
Monarch:6383 SDC2
NCBI Gene:6383 SDC2
OMIM:142460 SDC2
UCSC:P34741 SDC2
Reference Transcript
Other Identifiers
11720753_s_at
11745006_a_at
11745007_s_at
11746797_a_at
11746798_x_at
11751122_x_at
17071144
212154_at
212157_at
212158_at
3108152
3108153
3108154
3108155
3108156
3108157
3108158
3108184
3108185
3108186
3108187
3108188
3108189
3108190
3108191
3108192
3108210
3108212
39757_at
6383
65000_at
8147461
A_14_P109550
A_24_P380734
A_33_P3371219
GE57514
GO:0000902
GO:0001523
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005764
GO:0005773
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0005886
GO:0006024
GO:0006027
GO:0006464
GO:0006629
GO:0007165
GO:0007399
GO:0008150
GO:0009056
GO:0009058
GO:0009986
GO:0016020
GO:0016021
GO:0016477
GO:0030154
GO:0030165
GO:0031012
GO:0040011
GO:0042802
GO:0043202
GO:0043226
GO:0043687
GO:0044267
GO:0048013
GO:0048813
GO:0048814
GO:0048856
GO:0048870
GO:0050900
GO:0062023
Hs.1501.0.S1_3p_at
Hs.1501.0.S2_3p_at
Hs.1501.0.S3_3p_at
ILMN_1784553
J04621_at
PH_hs_0000201
TC08000590.hg
Participant Of
hasMember
Other forms of this molecule
p-Y179,Y191-SDC2 [plasma membrane]
p-SDC2 [endoplasmic reticulum lumen]
SDC2 [endoplasmic reticulum lumen]
SDC2 [plasma membrane]
SDC2 [lysosomal lumen]
HS(5)-SDC2 [plasma membrane]
HS(3)-SDC2 [plasma membrane]
HS(1)-SDC2 [plasma membrane]
HS(2)-SDC2 [plasma membrane]
HS(6)-SDC2 [plasma membrane]
HS(4)-SDC2 [plasma membrane]
HS(6)-SDC2 [Golgi lumen]
HS(5)-SDC2 [Golgi lumen]
Heparan-SDC2 [Golgi lumen]
XylS-SDC2 [Golgi lumen]
Gal-Xyl-SDC2 [Golgi lumen]
SDC2 [Golgi lumen]
Gal-Gal-Xyl-SDC2 [Golgi lumen]
GlcA-Gal-Gal-Xyl-SDC2 [Golgi lumen]
HS(3)-SDC2 [Golgi lumen]
HS(4)-SDC2 [Golgi lumen]
HS(2)-SDC2 [Golgi lumen]
HS(1)-SDC2 [Golgi lumen]
Heparan(4)-SDC2 [Golgi lumen]
Heparan(3)-SDC2 [Golgi lumen]
Heparan(2)-SDC2 [Golgi lumen]
Heparan(1)-SDC2 [Golgi lumen]
Inferred To
sdn-1 [lysosomal lumen] (Caenorhabditis elegans)
SDC2 [lysosomal lumen] (Canis familiaris)
SDC2 [lysosomal lumen] (Gallus gallus)
SDC2 [lysosomal lumen] (Sus scrofa)
sdc2 [lysosomal lumen] (Danio rerio)
Sdc [lysosomal lumen] (Drosophila melanogaster)
Sdc2 [lysosomal lumen] (Mus musculus)
Sdc2 [lysosomal lumen] (Rattus norvegicus)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63666) at unknown position
Modification
beta-D-IdoA-(1->4)-alpha-D-GlcNS6S-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
HMDB Protein
PDB
Interactors (18)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P34741 SDC2  28 0.655 4
 UniProt:P41271-2 NBL1      0.556 3
 UniProt:Q7Z699 SPRED1  2 0.556 3
 UniProt:Q13387-4 MAPK8IP2      0.556 3
 UniProt:Q9Y3C5 RNF11      0.556 3
 UniProt:G5E9A7 G5E9A7      0.556 3
 UniProt:P27986-2 PIK3R1      0.556 3
 UniProt:Q6NXG1 ESRP1  3 0.556 3
 UniProt:P28799 GRN  2 0.556 3
 UniProt:O60784-2 TOM1      0.556 3
 IntAct:EBI-25834291 CCSB      0.556 3
 UniProt:O60333-2 KIF1B      0.556 3
 UniProt:O60506-4 SYNCRIP      0.556 3
 UniProt:Q12797-6 ASPH      0.556 5
 UniProt:P28799-2 GRN      0.556 3
 UniProt:O15354 GPR37  1 0.556 3
 UniProt:O76024 WFS1  3 0.556 3
 UniProt:O14936 CASK  1 0.527 2
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