Reactome: A Curated Pathway Database

p75NTR:NgR complex interacts with the axonal inhibitor LINGO1

Stable Identifier
R-HSA-209573
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The NgR1:p75NTR complex also interacts with LINGO1, a nervous system-specific transmembrane protein. LINGO1 is a potent axonal inhibitor of oligodendrocyte differentiation and myelination, and is regulated by NGF and its receptor TRKA .

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events