Noradrenaline is converted to adrenaline

Stable Identifier
R-HSA-209903
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Phenylethanolamine N-methyltransferase (PNMT) is the terminal enzyme in catecholamine biosynthesis. It performs transmethylation of noradrenaline to adrenaline using S-adenosyl L-methionine (SAM) as the methyl donor.

Literature References
PubMed ID Title Journal Year
3372503 Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesis

Kaneda, N, Ichinose, H, Kobayashi, K, Oka, K, Kishi, F, Nakazawa, A, Kurosawa, Y, Fujita, K, Nagatsu, T

J Biol Chem 1988
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
phenylethanolamine N-methyltransferase activity of PNMT [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created