Catecholamine biosynthesis

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R-HSA-209905
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Pathway
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Homo sapiens
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The catecholamine neurotransmitters dopamine, noradrenaline and adrenaline are found in nervous tissue of animals. They are synthesized in catecholaminergic neurons by four enzymes from tyrosine to adrenaline: tyrosine hydroxylase (TH); aromatic L-amino acid decarboxylase (AADC); dopamine beta-hydroxylase (DBH); and phenylethanolamine N-methyltransferase (PNMT).

Literature References
PubMed ID Title Journal Year
1684650 Genes for human catecholamine-synthesizing enzymes

Nagatsu, T

Neurosci Res 1991
363400 Catecholamines: role in health and disease

Laverty, R

Drugs 1978
10691773 Catecholamine biosynthesis and physiological regulation in neuroendocrine cells

Flatmark, T

Acta Physiol Scand 2000
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