Serotonin and melatonin biosynthesis

Stable Identifier
R-HSA-209931
Type
Pathway
Species
Homo sapiens
Compartment
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Summation

Serotonin (5-HT) is a hormone and neurotransmitter used for regulatory purposes in animal CNS. In the human brain, serotonin is involved in many physiological functions such as sleep, pain, mood and is the precursor to melatonin, a hormone produced in the pineal gland.

Literature References
PubMed ID Title Journal Year
16942634 Tryptophan metabolism in the central nervous system: medical implications

Ruddick, JP, Evans, AK, Nutt, DJ, Lightman, SL, Rook, GA, Lowry, CA

Expert Rev Mol Med 2006
18155917 Melatonin in the skin: synthesis, metabolism and functions

Slominski, A, Tobin, DJ, Zmijewski, MA, Wortsman, J, Paus, R

Trends Endocrinol Metab 2008
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Orthologous Events
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BioModels Database
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