Tyrosine is diiodinated

Stable Identifier
R-HSA-209973
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Tyrosine is diiodinated
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Tyrosines can be iodinated in thyroglobulin to produce precursors for thyroid hormone synthesis.

Literature References
PubMed ID Title Journal Year
67547 Biosynthesis of thyroid hormone: basic and clinical aspects

Degroot, LJ, Niepomniszcze, H

Metabolism 1977
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
peroxidase activity of TPO [plasma membrane]
Physical Entity
TPO [plasma membrane]
Activity
peroxidase activity (0004601)
Orthologous Events
Tyrosine is diiodinated (Bos taurus)
Tyrosine is diiodinated (Caenorhabditis elegans)
Tyrosine is diiodinated (Canis familiaris)
Tyrosine is diiodinated (Dictyostelium discoideum)
Tyrosine is diiodinated (Drosophila melanogaster)
Tyrosine is diiodinated (Gallus gallus)
Tyrosine is diiodinated (Mus musculus)
Tyrosine is diiodinated (Rattus norvegicus)
Tyrosine is diiodinated (Xenopus tropicalis)
Authored
Jassal, B  (2008-10-01)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-01-08)
Cite Us!