NEUROG3-dependent synthesis of PAX4 protein

Stable Identifier
R-HSA-210886
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NEUROG3-dependent synthesis of PAX4 protein
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The PAX4 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus. PAX4 transcription requires the activity of the NEUROG3 transcription factor (Heremans et al. 2002; Mellitzer et al. 2006).
Literature References
PubMed ID Title Journal Year
16511571 IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

Mellitzer, G, Lan, M, Mansouri, A, Lee, J, Lenne-Samuel, N, Luco, RF, Gradwohl, G, Bonne, S, Van De Casteele, M, Ferrer, J, Collombat, P, Pipeleers, D, Heimberg, H, Nielsen, FC

EMBO J 2006
12403815 Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

Serup, P, Madsen, OD, Gradwohl, G, Van De Casteele, M, Pipeleers, D, in't Veld, P, Heremans, Y, Heimberg, H

J Cell Biol 2002
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NEUROG3 [nucleoplasm] (Homo sapiens)
Authored
Tello-Ruiz, MK  (2008-05-24)
Ferrer, J  (2008-05-24)
Reviewed
Jensen, J  (2008-05-13)
Created
D'Eustachio, P  (2008-01-17)
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