Reactome | Phosphorylated FOXO1A is excluded from the nucleus

Phosphorylated FOXO1A is excluded from the nucleus

Stable Identifier

R-HSA-211178

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nucleoplasm, cytosol

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Phosphorylated FOXO1A is excluded from the nucleus

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Phosphorylated FOXO1A is transported from the nucleoplasm to the cytosol (Zhang et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
12228231	Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding Zhang, X, Gan, L, Pan, H, Guo, S, He, X, Olson, ST, Mesecar, A, Adam, S, Unterman, TG	J Biol Chem	2002