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DFFA(118-331) [nucleoplasm]
Stable Identifier
R-HSA-211199
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DFF45 (fragment 118-331)
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptosis induced DNA fragmentation (Homo sapiens)
Caspase 3-mediated cleavage of DFF45 (117) (Homo sapiens)
Caspase cleaved DFFA (117) [nucleoplasm] (Homo sapiens)
DFFA(118-331) [nucleoplasm] (Homo sapiens)
Cleavage of DFF45 (224) by caspase-3 (Homo sapiens)
Caspase cleaved DFFA (117) [nucleoplasm] (Homo sapiens)
DFFA(118-331) [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00273 DFFA
Gene Names
DFFA, DFF1, DFF45, H13
Chain
chain:1-331
Reference Genes
BioGPS Gene:1676 DFFA
COSMIC (genes):DFFA DFFA
CTD Gene:1676 DFFA
dbSNP Gene:1676 DFFA
ENSEMBL:ENSG00000160049 DFFA
HGNC:2772 DFFA
KEGG Gene (Homo sapiens):1676 DFFA
Monarch:1676 DFFA
NCBI Gene:1676 DFFA
OMIM:601882 DFFA
UCSC:O00273 DFFA
Reference Transcript
RefSeq:NM_004401.2 DFFA
RefSeq:NM_213566.1 DFFA
Other Identifiers
0002120520
11726261_at
11726262_a_at
11726263_x_at
11739517_x_at
16681531
1676
18859
19938
1IBX
1IYR
1KOY
203277_3p_at
203277_at
223518_at
226116_at
2396120
2396122
2396123
2396124
2396125
2396126
2396127
2396128
2396129
2396130
2396131
2396132
2396133
2396134
25230
2679
32047_at
62173_at
7912303
86020_at
91741_at
A0A024R4H5
A_23_P12189
A_24_P222758
AAC51249
AAD32953
AAF02419
AAH00037
AAH07112
AAH07721
AAP35626
AF087573
AF103799
AK313317
AL354956
BAG36122
BC000037
BC007112
BC007721
BT006980
CAB002679
CCDS118
CCDS119
CH471130
DFFA
DFFA-201
DFFA-202
EAW71656
EAW71657
EAW71658
ENSG00000160049
ENSP00000366235
ENSP00000366237
ENST00000377036
ENST00000377036.2
ENST00000377038
ENST00000377038.7
EntrezGene:1676
EntrezGene:DFFA
g4758147_3p_at
g4758147_3p_x_at
g4926917_3p_at
GE59567
GE702566
GO:0000228
GO:0000790
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005811
GO:0005829
GO:0005886
GO:0006259
GO:0006309
GO:0006457
GO:0006915
GO:0008150
GO:0008219
GO:0009056
GO:0019904
GO:0030234
GO:0032076
GO:0034641
GO:0034655
GO:0043065
GO:0043226
GO:0044183
GO:0060703
GO:0061077
GO:0070242
GO:1900118
GO:1902511
HGNC:2772
HPA018859
HPA019938
HPA025230
Hs.48617.0.S1_3p_at
ILMN_1667213
ILMN_2385220
IPR003508
IPR015121
IPR017299
IPR027296
K7ERT1
MIM:601882
NM_004401
NM_213566
NP_004392
NP_998731
PF02017
PF09033
PH_hs_0003404
PH_hs_0026477
SM00266
TC01002190.hg
U91985
U91985_at
UPI000002A7D6
UPI00001291FA
Participant Of
hasComponent
Caspase cleaved DFFA (117) [nucleoplasm]
Other forms of this molecule
DFFA [cytosol]
DFFA(1-?) [nucleoplasm]
DFFA(225-331) [nucleoplasm]
DFFA(118-224) [nucleoplasm]
DFFA(1-117) [nucleoplasm]
Inferred To
DFFA(118-331) [nucleoplasm] (Bos taurus)
DFFA(118-331) [nucleoplasm] (Canis familiaris)
DFFA(118-331) [nucleoplasm] (Danio rerio)
DFFA(118-331) [nucleoplasm] (Gallus gallus)
DFFA(118-331) [nucleoplasm] (Mus musculus)
DFFA(118-331) [nucleoplasm] (Rattus norvegicus)
DFFA(118-331) [nucleoplasm] (Sus scrofa)
DFFA(118-331) [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
NP_998731.1
,
NP_004392.1
OpenTargets
ENSG00000160049
GeneCards
O00273
PRO
O00273
PDB
1IYR
,
1KOY
,
1IBX
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O76075 DFFB
2
DFFB [nucleoplasm]
(R-HSA-211195)
DFFB [cytosol]
(R-HSA-211211)
0.852
6
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.589
2
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.589
2
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P04792 HSPB1
3
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
HSPB1 [cytosol]
(R-HSA-450563)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.508
2
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