Reactome | FOXA3 [nucleoplasm]

FOXA3 [nucleoplasm]

Stable Identifier

R-HSA-211484

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Forkhead box protein A3, Hepatocyte nuclear factor 3-gamma

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P55318 FOXA3

Gene Names

FOXA3, HNF3G, TCF3G

Chain

chain:1-350

Reference Genes

BioGPS Gene:3171 FOXA3

COSMIC (genes):FOXA3 FOXA3

CTD Gene:3171 FOXA3

dbSNP Gene:3171 FOXA3

ENSEMBL:ENSG00000170608 FOXA3

HGNC:5023 FOXA3

KEGG Gene (Homo sapiens):3171 FOXA3

Monarch:3171 FOXA3

NCBI Gene:3171 FOXA3

OMIM:602295 FOXA3

UCSC:P55318 FOXA3

Reference Transcript

RefSeq:NM_004497.2 FOXA3

Other Identifiers

0000450035

11727662_at

16863370

228463_at

3171

3836536

3836537

3836539

3836540

3836541

45381_at

45382_g_at

52543_at

8029754

A_14_P101521

A_23_P142174

A_23_P208737

GE81402

GO:0000003

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001678

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005856

GO:0006325

GO:0006355

GO:0006357

GO:0006950

GO:0007275

GO:0007283

GO:0008134

GO:0008150

GO:0009058

GO:0009267

GO:0009653

GO:0015629

GO:0019904

GO:0030154

GO:0034641

GO:0042592

GO:0043226

GO:0043565

GO:0045944

GO:0048856

GO:0051276

GO:0061484

GO:1990837

HMNXSV003042384

Hs.36137.0.S2_3p_at

ILMN_1792733

ILMN_1804041

PH_hs_0002892

TC19000656.hg

Participates

as an output of

HNF1A-dependent synthesis of FOXA3 (Homo sapiens)

Cross References

RefSeq

NP_004488.2

OpenTargets

ENSG00000170608

HPA

ENSG00000170608-FOXA3

GeneCards

P55318

Ensembl

ENST00000302177, ENSG00000170608, ENSP00000304004

PRO

P55318

Orphanet

24546

PDB

1VTN

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22607 FGFR3	40	FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 795fs139 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419) p-6Y-FGFR3 S371C [plasma membrane] (R-HSA-2011886) p-6Y-FGFR3 G370C [plasma membrane] (R-HSA-2011883) p-6Y-FGFR3 Y373C [plasma membrane] (R-HSA-2011889) p-6Y-FGFR3 795fs139 [plasma membrane] (R-HSA-2038360) p-6Y-FGFR3 R248C [plasma membrane] (R-HSA-2011884) pY-FGFR3 [plasma membrane] (R-HSA-2038368) p-6Y-FGFR3 K650Q [plasma membrane] (R-HSA-2032962) p-6Y-FGFR3 K650N [plasma membrane] (R-HSA-2032961) p-6Y-FGFR3 K650E [plasma membrane] (R-HSA-2032952) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-4Y FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853147) p-4Y FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853155) p-4Y FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853145) p-4Y FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853129) p-4Y FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853151) p-4Y FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853128) FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127)	0.556	3
UniProt:P28329-3 P283293			0.556	3

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