Eicosanoids

Stable Identifier
R-HSA-211979
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Pathway
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Homo sapiens
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Arachidonic acid is metabolized via three major enzymatic pathways: cyclooxygenase, lipoxygenase, and cytochrome P450. The cytochrome P450 pathway metabolites are oxygenated metabolites of arachidonic acid.

Literature References
PubMed ID Title Journal Year
15102545 57 varieties: the human cytochromes P450

Lewis, DF

Pharmacogenomics 2004
7922394 Prostaglandins, thromboxanes, leukotrienes, and cytochrome P-450 metabolites of arachidonic acid

Cook, JA, Geisel, J, Halushka, PV, Reines, HD

New Horiz 1993
16584116 Cytochrome P450s and other enzymes in drug metabolism and toxicity

Guengerich, FP

AAPS J 2006
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