Reactome | RBBP7 [nucleoplasm]

RBBP7 [nucleoplasm]

Stable Identifier

R-HSA-212227

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RbAp46

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Locations in the PathwayBrowser for interactor UniProt:Q96ST3 SIN3A

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External Reference Information

External Reference

UniProt:Q16576 RBBP7

Gene Names

RBBP7, RBAP46

Chain

initiator methionine:1, initiator methionine:, chain:2-425

Reference Genes

BioGPS Gene:5931 RBBP7

COSMIC (genes):RBBP7 RBBP7

CTD Gene:5931 RBBP7

dbSNP Gene:5931 RBBP7

ENSEMBL:ENSG00000102054 RBBP7

HGNC:9890 RBBP7

KEGG Gene (Homo sapiens):5931 RBBP7

Monarch:5931 RBBP7

NCBI Gene:5931 RBBP7

OMIM:300825 RBBP7

UCSC:Q16576 RBBP7

Reference Transcript

Other Identifiers

0005390088

11715433_a_at

17109396

201092_at

3981265

4000946

4000947

4000948

4000949

4000951

4000953

4000955

4000958

4000960

4000963

4000966

4000967

4000968

4000970

4000973

4000975

4000976

4000977

4000978

4000979

41515_at

5931

8171516

A_23_P114221

GE59981

GO:0000122

GO:0000228

GO:0003674

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006260

GO:0006325

GO:0006464

GO:0006950

GO:0007049

GO:0007165

GO:0008150

GO:0009058

GO:0016581

GO:0022607

GO:0030308

GO:0032991

GO:0034080

GO:0034641

GO:0035098

GO:0040007

GO:0043226

GO:0043687

GO:0045814

GO:0045892

GO:0048545

GO:0051276

GO:0065003

GO:0070317

GO:0070370

GO:1901796

ILMN_1770053

PH_hs_0019247

TC0X000886.hg

X72841_at

g13259504_3p_at

Participant Of

hasMember

hasComponent

input

Inferred To

Ghost homologue of RBBP7 [nucleoplasm] (Bos taurus)

Rbbp7 [nucleoplasm] (Mus musculus)

Rbbp7 [nucleoplasm] (Rattus norvegicus)

RBBP7 [nucleoplasm] (Canis familiaris)

RBBP7 [nucleoplasm] (Plasmodium falciparum)

RBBP7 [nucleoplasm] (Sus scrofa)

rbbp7 [nucleoplasm] (Danio rerio)

rbbp7 [nucleoplasm] (Xenopus tropicalis)

mis16 [nucleoplasm] (Schizosaccharomyces pombe)

rbbD [nucleoplasm] (Dictyostelium discoideum)

Homologues of RBBP7 [nucleoplasm] (Plasmodium falciparum)

Caf1-55 [nucleoplasm] (Drosophila melanogaster)

HAT2 [nucleoplasm] (Saccharomyces cerevisiae)

lin-53 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001185648.1, NP_002884.1

OpenTargets

ENSG00000102054

HPA

ENSG00000102054-RBBP7

GeneCards

Q16576

Ensembl

ENSG00000102054, ENSP00000369427, ENST00000380084, ENST00000380087, ENSP00000369424

PRO

Q16576

PDB

3CFV, 3CFS

Interactors (42)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	SUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030) HDAC1 [nucleoplasm] (R-HSA-205021)	0.886	7
UniProt:O94776 MTA2	1	MTA2 [nucleoplasm] (R-HSA-4657009)	0.88	11
UniProt:P62805 H4C1	19	SUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) HIST1H4A [extracellular region] (R-HSA-977569) SUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-4568749) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) MeK-HIST1H4A [nucleoplasm] (R-HSA-2172676) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652)	0.793	9
UniProt:Q15022 SUZ12	2	SUMO1-K75-SUZ12 [nucleoplasm] (R-HSA-4615932) SUZ12 [nucleoplasm] (R-HSA-212217)	0.725	5
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) SUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.725	4
UniProt:Q9Y294 ASF1A	1	ASF1A [nucleoplasm] (R-HSA-417169)	0.725	4
UniProt:O14519 CDKA1			0.725	4
UniProt:O95983 MBD3	1	MBD3 [nucleoplasm] (R-HSA-4657010)	0.69	4
UniProt:Q9Y483 MTF2	1	MTF2 [nucleoplasm] (R-HSA-5084119)	0.643	4
UniProt:Q9BTC8 MTA3	1	MTA3 [nucleoplasm] (R-HSA-4657013)	0.643	3
UniProt:O75446 SAP30	1	SAP30 [nucleoplasm] (R-HSA-351693)	0.643	3
UniProt:Q15910 EZH2	1	EZH2 [nucleoplasm] (R-HSA-212298)	0.643	4
UniProt:Q13330 MTA1	2	SUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537) MTA1 [nucleoplasm] (R-HSA-3465550)	0.643	3
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) SUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.643	3
UniProt:Q8WXI9 GATAD2B	1	GATAD2B [nucleoplasm] (R-HSA-3702079)	0.643	3
UniProt:P68431 H3C1	59	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) HIST1H3A [extracellular region] (R-HSA-977570) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) AcK19-HIST1H3A [nucleoplasm] (R-HSA-4568761) AcK5-HIST1H3A [nucleoplasm] (R-HSA-4568751) AcK24-HIST1H3A [nucleoplasm] (R-HSA-4568754) AcK15-HIST1H3A [nucleoplasm] (R-HSA-4568743) Ack15-HIST1H3A [nucleoplasm] (R-HSA-4549217) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5229050) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4754188) Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4754169) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791) Me3K80-HIST1H3A [nucleoplasm] (R-HSA-5649795) Me2K80-HIST1H3A [nucleoplasm] (R-HSA-5649768) Me3K37-HIST1H3A [nucleoplasm] (R-HSA-5638160) Me2K37-HIST1H3A [nucleoplasm] (R-HSA-4722125) MeK10-HIST1H3A [nucleoplasm] (R-HSA-212105) MeK28-HIST1H3A [nucleoplasm] (R-HSA-5638327) MeK-10-HIST1H3A [cytosol] (R-HSA-8943830) HIST1H3A [cytosol] (R-HSA-8943829) Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-5244526) MeK5-HIST1H3A [nucleoplasm] (R-HSA-4687016) Cit27-HIST1H3A [nucleoplasm] (R-HSA-5246532) Cit3-HIST1H3A [nucleoplasm] (R-HSA-5246544) Cit9-HIST1H3A [nucleoplasm] (R-HSA-5246530) Cit18-HIST1H3A [nucleoplasm] (R-HSA-5246534) MeR18-HIST1H3A [nucleoplasm] (R-HSA-5229059) MeR3-HIST1H3A [nucleoplasm] (R-HSA-5244529) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5244801) MeR9-HIST1H3A [nucleoplasm] (R-HSA-5244806) Ack10-HIST1H3A [nucleoplasm] (R-HSA-4568939) Me2K10-HIST1H3A [nucleoplasm] (R-HSA-427378) Me2K5,Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-8936572) p-T12, Me2K-10-HIST1H3A [nucleoplasm] (R-HSA-5625790) p-T12-HIST1H3A [nucleoplasm] (R-HSA-5625872) p-T12,MeK-10-HIST1H3A [nucleoplasm] (R-HSA-5625859) p-T12, Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-5625757) Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-427734) Me3K5-HIST1H3A [nucleoplasm] (R-HSA-1214186) HIST1H3A [nucleoplasm] (R-HSA-212070) Me3K-28-HIST1H3A [nucleoplasm] (R-HSA-212220) Me2K5-HIST1H3A [nucleoplasm] (R-HSA-1214170)	0.643	3
UniProt:Q9NVP2 ASF1B			0.643	3
IntAct:EBI-15650351 H3TAIL			0.591	3
UniProt:Q12873 CHD3	2	SUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372) CHD3 [nucleoplasm] (R-HSA-4657012)	0.577	5
UniProt:Q96QT6 PHF12			0.527	2
UniProt:Q5PSV4 BRM1L			0.527	2
UniProt:Q6ZN18 AEBP2	1	AEBP2 [nucleoplasm] (R-HSA-5082342)	0.527	2
UniProt:Q9R190 Mta2	1	Mta2 [nucleoplasm] (R-MMU-5096453)	0.527	2
UniProt:Q92800 EZH1			0.527	2
UniProt:Q9HCU9 BRMS1	1	BRMS1 [nucleoplasm] (R-HSA-4650034)	0.527	2
UniProt:O14929 HAT1	1	HAT1 [nucleoplasm] (R-HSA-3662337)	0.527	2
UniProt:Q9HAJ7 SAP30L	1	SAP30L [nucleoplasm] (R-HSA-351698)	0.527	2
UniProt:Q8WUU5 GATD1			0.527	2
UniProt:O75182 SIN3B	1	SIN3B [nucleoplasm] (R-HSA-3006450)	0.527	2
UniProt:Q86YP4 GATAD2A	1	GATAD2A [nucleoplasm] (R-HSA-3702077)	0.527	2
UniProt:Q9NP50 SHCAF			0.527	2
UniProt:O43189 PHF1	1	PHF1 [nucleoplasm] (R-HSA-5084105)	0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q9UBB5 MBD2	1	MBD2 [nucleoplasm] (R-HSA-427367)	0.527	2
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.527	3
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.527	3
UniProt:O75530 EED	1	EED [nucleoplasm] (R-HSA-212278)	0.527	3
UniProt:P62799 H4			0.524	2
UniProt:Q17R98 ZN827			0.499	2
UniProt:P12520 VPR			0.462	4
UniProt:Q8N5A5 ZGPAT			0.462	2
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.462	3

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