Caspase 3-mediated cleavage of PKC delta

Stable Identifier
R-HSA-212552
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Caspase mediated cleavage produces a constitutively active kinase that induces apoptosis (Ghayur et al.,1996).

Literature References
PubMed ID Title Journal Year
8976194 Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

Ghayur, T, Hugunin, M, Talanian, RV, Ratnofsky, S, Quinlan, C, Emoto, Y, Pandey, P, Datta, R, Huang, Y, Kharbanda, S, Allen, H, Kamen, R, Wong, W, Kufe, D

J Exp Med 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cysteine-type endopeptidase activity of Caspase-3 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created