Caspase 3-mediated cleavage of PKC delta

Stable Identifier
R-HSA-212552
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Caspase mediated cleavage produces a constitutively active kinase that induces apoptosis (Ghayur et al.,1996).
Literature References
PubMed ID Title Journal Year
8976194 Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

Wong, W, Ghayur, T, Huang, Y, Ratnofsky, S, Hugunin, M, Emoto, Y, Kharbanda, S, Kufe, D, Kamen, R, Quinlan, C, Pandey, P, Talanian, RV, Allen, H, Datta, R

J Exp Med 1996
Participants
Participates
Catalyst Activity

cysteine-type endopeptidase activity of Caspase-3 [cytosol]

Orthologous Events
Authored
Reviewed
Created
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