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EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
Stable Identifier
R-HSA-212717
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Activated EGFR:PLC-gamma1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by EGFR (Homo sapiens)
EGFR interacts with phospholipase C-gamma (Homo sapiens)
EGFR activates PLC-gamma1 by phosphorylation (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
Phospholipase C-gamma1 binds to the activated EGF receptor (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Homo sapiens)
Participants
components
EGF-like ligands:p-6Y EGFR dimer [plasma membrane]
(Homo sapiens)
PLCG1 [cytosol]
(Homo sapiens)
Participates
as an output of
Phospholipase C-gamma1 binds to the activated EGF receptor (Homo sapiens)
as an input of
EGFR activates PLC-gamma1 by phosphorylation (Homo sapiens)
Inferred To
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Bos taurus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Canis familiaris)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Danio rerio)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Gallus gallus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Mus musculus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Sus scrofa)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(Xenopus tropicalis)
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