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FCER2(1-321) [plasma membrane]
Stable Identifier
R-HSA-2127280
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
FCER2, Low affinity immunoglobulin epsilon Fc receptor, CD23A, CD23
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-10 signaling (Homo sapiens)
IL10 negatively regulates plasma membrane-associated inflammatory mediators (Homo sapiens)
IL10-downregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
FCER2(1-321) [plasma membrane] (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
Expression of IL13-upregulated plasma membrane proteins (Homo sapiens)
IL13-upregulated proteins [plasma membrane] (Homo sapiens)
FCER2(1-321) [plasma membrane] (Homo sapiens)
Expression of STAT6-upregulated plasma membrane proteins (Homo sapiens)
STAT6 upregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
FCER2(1-321) [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH2 (Homo sapiens)
NOTCH2 intracellular domain regulates transcription (Homo sapiens)
NOTCH2 stimulates transcription of FCER2 (CD23A) (Homo sapiens)
FCER2(1-321) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06734 FCER2
Gene Names
FCER2, CD23A, CLEC4J, FCE2, IGEBF
Chain
chain:1-321, chain:150-321
Reference Genes
BioGPS Gene:2208 FCER2
COSMIC (genes):FCER2 FCER2
CTD Gene:2208 FCER2
dbSNP Gene:2208 FCER2
ENSEMBL:ENSG00000104921 FCER2
ENSEMBL_homo_sapiens_GENE:ENSG00000104921.15 FCER2
HGNC:3612 FCER2
KEGG Gene (Homo sapiens):2208 FCER2
Monarch:2208 FCER2
NCBI Gene:2208 FCER2
OMIM:151445 FCER2
UCSC:P06734 FCER2
Reference Transcript
RefSeq:NM_001207019.2 FCER2
RefSeq:XM_005272462.4 FCER2
RefSeq:NM_002002.4 FCER2
RefSeq:NM_001220500.1 FCER2
Other Identifiers
11756817_a_at
16867975
206759_PM_at
206759_at
206760_PM_s_at
206760_s_at
2208
34959_at
34960_g_at
3848494
3848495
3848496
3848497
3848498
3848499
3848500
3848502
3848503
3848505
3848506
3848508
3848510
3848512
3848513
3848517
3848519
3848522
8033420
GE57838
GO:0002376
GO:0002450
GO:0002925
GO:0005178
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006955
GO:0009897
GO:0012501
GO:0016020
GO:0016192
GO:0019769
GO:0019863
GO:0023052
GO:0030246
GO:0038095
GO:0042116
GO:0043226
GO:0046872
GO:0051000
GO:0051712
GO:0051770
GO:0060089
GO:0070062
GO:0160006
HMNXSV003043691
ILMN_1662451
M15059_at
PH_hs_0000188
TC19001116.hg
g4503678_3p_a_at
Participates
as a member of
IL13-upregulated proteins [plasma membrane] (Homo sapiens)
STAT6 upregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
IL10-downregulated plasma membrane proteins [plasma membrane] (Homo sapiens)
as an output of
NOTCH2 stimulates transcription of FCER2 (CD23A) (Homo sapiens)
Cross References
RefSeq
XP_005272519.1
,
NP_001193948.2
,
NP_001207429.1
,
NP_001993.2
Guide to Pharmacology - Targets
2935
OpenTargets
ENSG00000104921
ZINC - Substances
FCER2_HUMAN
ZINC target
P06734
PRO
P06734
PDB
1T8D
,
6Y0L
,
1T8C
,
4KI1
,
5LGK
,
4EZM
,
4GJX
,
4J6N
,
4J6Q
,
4GK1
,
4GKO
,
4J6P
,
4GJ0
,
4GI0
,
4G9A
,
4J6K
,
2H2R
,
4J6J
,
4G96
,
2H2T
,
4J6M
,
6Y0M
,
4J6L
ZINC - Investigational
FCER2_HUMAN
GeneCards
P06734
HPA
ENSG00000104921-FCER2
Ensembl
ENSP00000264072
,
ENST00000346664
,
ENSG00000104921
,
ENST00000597921
,
ENSP00000471974
Pharos - Targets
P06734
ZINC - Predictions - Purchasable
FCER2_HUMAN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17544 ATF7
0.556
3
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